School of Medicine
Showing 1-10 of 44 Results
-
Yiyun Chen
Postdoctoral Scholar, Stanford Cancer Center
BioYiyun Chen, Ph.D. is a Postdoctoral Fellow at Professor Crystal Mackall’s group at Stanford Cancer Institute.
Dr. Chen studied biochemistry and structural biology in her undergraduate and master trainings at The Hong Kong University of Science and Technology, where she eventually obtained her Ph.D. degree in computational biology under the supervision of Professor Jiguang Wang. During her Ph.D. training, she has developed her skill sets in analyzing and integrating various types of patient-derived sequencing data, published three first-author and four co-author papers, and received two awards for top postgraduate students. Through interdisciplinary collaborations with cancer biologist and clinicians in US and Asia, her work has uncovered tumor-specific immune cell subtypes and novel noncoding RNAs and generated new insights into precision medicine in glioma, lymphoma and gastric cancer.
Applying her expertise in computational cancer biology and immunology, her current research is focused on identifying molecular mechanisms that contribute to the clinical outcomes of patients undergoing CAR-T immunotherapy. At Mackall Lab, she will contribute to tailoring computational pipelines for profiling the spatiotemporal dynamics of the tumor and immune microenvironment and translate new discoveries into cancer therapeutics. -
Zinaida Good, Ph.D.
Instructor, Stanford Institutes of Medicine
Postdoctoral Scholar, Stanford Cancer CenterBioZinaida Good, Ph.D. is a postdoctoral fellow working at the intersection of systems biology and cancer immunotherapy at Stanford University. Good’s research with Crystal L. Mackall and Sylvia K. Plevritis is focused on investigating why engineered cellular immunotherapies succeed or fail in patients. Leveraging multimodal single-cell analysis, tumor microenvironment imaging, and data integration, she aims to identify features of optimal engineered T cells from patient data. Good earned her doctorate in computational and systems immunology from Stanford University in 2018, where she trained with Garry P. Nolan and Sean C. Bendall. Her background is in immunology — with bachelor’s and master’s degrees from the University of British Columbia — and oncology, having worked for two years in discovery oncology at Genentech. Good is an inventor on two patent applications, has co-authored 12 papers, published four first-author manuscripts (Good and Sarno et al. Nature Medicine, 2018; Good et al. Nature Biotechnology, 2019; Good et al. Trends in Immunology, 2019; Good and Spiegel et al. Nature Medicine, 2022), and has been named a Parker Institute for Cancer Immunotherapy Scholar, a Stanford Cancer Institute Fellow, and an Arthur and Sandra Irving Cancer Immunology Fellow. Good’s long-term goal is to understand and enhance engineered cellular immunotherapies for patients with cancer.
