School of Medicine
Showing 11-20 of 659 Results
Mrs. George A. Winzer Professor in Cell Biology
Current Research and Scholarly InterestsCELLULAR INFORMATION PROCESSING The main problem in signal transduction is to understand how different receptor-stimuli specifically control diverse cell functions. We are using automated microscopy, live-cell fluorescent biosensors and perturbations of predicted signaling proteins to systematically dissect signaling networks. This allows us to identify signaling modules and to elucidate and ultimately model the flow of cellular information.
M Bruce MacIver
Professor (Research) of Anesthesiology, Perioperative and Pain Medicine
Current Research and Scholarly InterestsWe study drug effects on the nervous system. Cellular, synaptic and molecular drug actions are investigated using electrophysiological and pharmacological tools in cortical/hippocampal brain slice preparations. We are also interested in mechanisms of neuronal integration and synchronization, especially related to patterns of EEG activity seen in vivo and in brain slices.
Michael P. Marks, MD
Professor of Radiology (General Radiology) and, by courtesy, of Neurosurgery
Current Research and Scholarly InterestsInterventional neuroradiology; cerebral arteriovenous malformations; stroke treatment and imaging; cerebral aneurysms
David B. McKay
Professor of Structural Biology, Emeritus
Current Research and Scholarly InterestsThree-dimensional structure determination and biophysical studies of macromolecules.
Uel Jackson McMahan
Professor of Neurobiology and of Structural Biology, Emeritus
Current Research and Scholarly InterestsWe are currently investigating mechanisms involved in synaptic transmission and synaptogenesis using electron microscope tomography in ways that provide in situ 3D structural information at macromolecular resolution.
Professor of Microbiology and Immunology, Emeritus
Current Research and Scholarly InterestsMy research interests focus on the biology and pathogenesis of cytomegalovirus (CMV), an opportunistic pathogen that causes significant disease worldwide. We developed global approaches and produced key insights into the areas of CMV gene regulation, DNA replication and packaging, maturation, impact on the host cell, disease pathogenesis, latency and reactivation, host cell signaling and chemokine system. These diverse findings address key aspects of the virus-host interaction.
Richard B. Moss
Professor of Pediatrics at the Lucile Salter Packard Children's Hospital, Emeritus
Current Research and Scholarly InterestsImmunopathogenesis of chronic airways diseases of childhood, including cystic fibrosis, asthma, allergic aspergillosis and bronchopulmonary dysplasia. Translational research: early clinical trials in airways disease of childhood, most notably CF, including gene, cytokine and drug therapy.
Professor of Medicine (Biomedical Informatics Research) and of Biomedical Data Science
Current Research and Scholarly InterestsThere are great opportunities for new discoveries and for ensuring the reproducibility of scientific results when experimental data—and descriptions of the methods used to generate and analyze those data—are available in public repositories. Our laboratory is studying the development of new methods to aid investigators in creating more comprehensive online descriptions both of their data and of their experiments that can be processed both by other scientists and by computers.
D. Craig Miller, MD
Thelma and Henry Doelger Professor in Cardiovascular Surgery
Current Research and Scholarly InterestsCardiac and heart valve disease with experimental laboratory large animal projects focused on the investigation of left ventricular and cardiac mechanics, bioenergetics, and LV and mitral valve physiology and pathophysiology. Current thrust is aimed at understanding the mitral valve and subvalvular mitral apparatus and transmural LV wall strains, thickening, and myolaminar fiber-sheet mechanics.
Clinical research interests include thoracic aortic diseases (aortic dissection, aneurysm) and cardiac valvular disease, including surgical treatment, endovascular thoracic aortic stent-graft repair, mitral valve repair, and valve-sparing aortic root replacement.