School of Medicine
Showing 51-60 of 83 Results
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Hylton Molzof, PhD, MPH
Clinical Assistant Professor, Psychiatry and Behavioral Sciences - Sleep Medicine
BioDr. Molzof is a Clinical Assistant Professor and Licensed Psychologist in the Department of Psychiatry and Behavioral Sciences, Stanford School of Medicine. She specializes in the assessment and treatment of sleep disorders via behavioral sleep medicine interventions, including Cognitive Behavioral Therapy for Insomnia (CBT-I) and positive airway pressure (PAP) desensitization. She also utilizes evidence-based techniques to help patients better manage circadian rhythm disorders, such as delayed sleep-wake phase disorder and shift work sleep disorder. Inspired by her background in public health, she has a strong interest in quality improvement and program development projects aimed at enhancing the quality and accessibility of sleep and circadian medicine for the diverse patient population served by Stanford Sleep Medicine Center.
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Seiji Nishino
Professor (Research) of Psychiatry & Behavioral Sciences, Emeritus
Current Research and Scholarly InterestsThe research focus of the Sleep and Circadian Neurobiology (SCN) Laboratory is the study of the sleep and circadian physiology using various animal models. A portion of the research is carried out using rodent models of narcolepsy and circadian rhythm sleep disorders. The laboratory also carries out pharmacological studies aiming to develop new treatments for these sleep disorders.
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Maurice M. Ohayon, MD, DSc, PhD
Professor of Psychiatry and Behavioral Sciences (Sleep Medicine)
Current Research and Scholarly InterestsMain focus is epidemiology of sleep and psychiatric disorders in the general population and clinical settings: 1)sleep habits and patterns; 2) prevalence, diagnosis, co-morbidity, treatment and Public Health impact of sleep disorders; 3) pain, posttraumatic stress disorder, social phobia, panic disorder and generalized anxiety; 4) epidemiology of narcolepsy and hypersomnia.
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Sergiu P. Pasca
Kenneth T. Norris, Jr. Professor of Psychiatry and Behavioral Sciences and Bonnie Uytengsu and Family Director of the Stanford Brain Organogenesis Program
Current Research and Scholarly InterestsA critical challenge in understanding the intricate programs underlying development, assembly and dysfunction of the human brain is the lack of direct access to intact, functioning human brain tissue for detailed investigation by imaging, recording, and stimulation.
To address this, we are developing bottom-up approaches to generate and assemble, from multi-cellular components, human neural circuits in vitro and in vivo.
We introduced the use of instructive signals for deriving from human pluripotent stem cells self-organizing 3D cellular structures named brain region-specific spheroids/organoids. We demonstrated that these cultures, such as the ones resembling the cerebral cortex, can be reliably derived across many lines and experiments, contain synaptically connected neurons and non-reactive astrocytes, and can be used to gain mechanistic insights into genetic and environmental brain disorders. Moreover, when maintained as long-term cultures, they recapitulate an intrinsic program of maturation that progresses towards postnatal stages.
We also pioneered a modular system to integrate 3D brain region-specific organoids and study human neuronal migration and neural circuit formation in functional preparations that we named assembloids. We have actively applied these models in combination with studies in long-term ex vivo brain preparations to acquire a deeper understanding of human physiology, evolution and disease mechanisms.
We have carved a unique research program that combines rigorous in vivo and in vitro neuroscience, stem cell and molecular biology approaches to construct and deconstruct previously inaccessible stages of human brain development and function in health and disease.
We believe science is a community effort, and accordingly, we have been advancing the field by broadly and openly sharing our technologies with numerous laboratories around the world and organizing the primary research conference and the training courses in the area of cellular models of the human brain. -
Rafael Pelayo, MD
Clinical Professor, Psychiatry and Behavioral Sciences - Sleep Medicine
Current Research and Scholarly InterestsSleep Disorders in Adults and Children
