School of Medicine
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Professor of Biomedical Data Science and of Statistics
Current Research and Scholarly InterestsMy research is in applied statistics and biostatistics. I specialize in computer-intensive methods for regression and classification, bootstrap, cross-validation and statistical inference, and signal and image analysis for medical diagnosis.
Professor of Pediatrics (Cardiology)
Current Research and Scholarly InterestsAssessment of vascular health in children by non-invasive modalities
Exercise interventions in children with congenital and acquired heart disease
Use of telehealth to deliver interventions to children with congenital and acquired heart disease
Quality Improvement in Pediatric Echocardiography
Echocardiography and outcomes in congenital heart disease
Professor of Genetics, of Biology and, by courtesy, of Chemistry
Current Research and Scholarly InterestsWe develop chemogenetic and optogenetic technologies for probing and manipulating protein networks, cellular RNA, and the function of mitochondria and the mammalian brain. Our technologies draw from protein engineering, directed evolution, chemical biology, organic synthesis, high-resolution microscopy, genetics, and computational design.
Christina (Christy) Tise, MD, PhD
Assistant Professor of Pediatrics (genetics)
BioDr. Christina (Christy) Tise is a physician scientist and Assistant Professor in the Division of Medical Genetics at Stanford with subspecialty training in Clinical Biochemical Genetics. Dr. Tise has developed multiple research projects focused on the clinical impact of biochemical genetic conditions in pregnancy and newborn health, including a project focused on unforeseen diagnoses in individuals initially identified through state newborn screening which has resulted in a number of publications.
Dr. Tise also researches the genetic etiologies of recurrent pregnancy loss and the impact of inherited metabolic conditions on human reproduction. She is involved in several research initiatives including contributing to the development of TRIOS, a multi-site, NIH-funded research study to evaluate the genetic causes of recurrent pregnancy loss. In serving as the primary research mentor for a recent Masters of Genetic Counseling graduate, Dr. Tise’s research on carrier and newborn screening has highlighted areas of ancestry-related healthcare inequities specific to the field of Medical Genetics.
Dr. Tise’s primary academic and advocacy interests are embodied in this work, specifically the overlap between biochemical and molecular analysis, and the clinical utility of innovative technologies for diagnosis and treatment of genetic disease. This is an unbelievably thrilling time for the field of Medical Genetics, as it promises immense progress and opportunity for all fields of medicine, and Dr. Tise is determined, honored, and incredibly excited to be a part of it!
Research interests: newborn screening, carrier screening, prenatal screening, genetics of recurrent pregnancy loss, biochemical genetics, novel gene discovery, variant interpretation, founder populations, diagnostic genetic testing, bioethics, GWAS/ExWAS
Postdoctoral Scholar, Nephrology
BioDiana M. Tordoff, PhD, MPH is a postdoctoral scholar with The PRIDE Study (pridestudy.org) at the Stanford School of Medicine. She is an epidemiologist whose research focuses on LGBTQ+ health equity. Prior to joining The PRIDE Study, Diana was awarded an NIH Kirschstein National Research Service Fellowship for her doctoral dissertation, which examined the heterogeneity in HIV/STI prevalence, testing, and PrEP use among transgender and non-binary people and their partners in the US. Her interests include barriers and facilitators of healthcare access for LGBTQ+ communities, sexual and reproductive health, molecular epidemiology, the vaginal microbiome, and community-engaged research methods.
Professor of Medicine (Gastroenterology and Hepatology)
Current Research and Scholarly InterestsOur lab is focused on exploring the role of matrix in disease progression in non-alcoholic steatohepatitis (NASH), hepatocellular carcinoma and primary sclerosing cholangitis. Our goal is to uncover how biomechanical characteristics of the ECM affect mechano-sensation, and how these pathways could ultimately be targeted. We are also interested in aging and its effects on metabolic pathways and mitochondrial function leading to disease progression in NASH and HCC.