Stanford University
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Ellen Youngsoo Rim
Assistant Professor of Chemical Engineering
BioPlants are increasingly vulnerable to environmental stressors—such as pathogen infection, drought, and heat—from climate change. These challenges threaten global food security and limit the carbon sequestration potential of plants. Our research goal is to sustainably enhance plant productivity and resilience through protein engineering. We engineer proteins involved in plant immune and hormone signaling pathways using directed evolution in high-throughput single cell systems. Directed evolution is a synthetic biology approach that enables rapid development of proteins with novel or improved functions. We combine this approach with machine learning, which allows us to learn from large datasets generated during the directed evolution process. Engineered proteins are then introduced into plants to enhance crop yields and climate resilience.
