Stanford University
Showing 501-510 of 535 Results
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Irving Weissman
Virginia & D.K. Ludwig Professor of Clinical Investigation in Cancer Research, Professor of Pathology, and of Developmental Biology
Current Research and Scholarly InterestsStem cell and cancer stem cell biology; development of T and B lymphocytes; cell-surface receptors for oncornaviruses in leukemia. Hematopoietic stem cells; Lymphocyte homing, lymphoma invasiveness and metastasis; order of events from hematopoietic stem cells [HSC] to AML leukemia stem cells and blood diseases, and parallels in other tissues; discovery of tumor and pathogenic cell 'don't eat me' and 'eat me' signals, and translation into therapeutics.
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Chad S. Weldy, M.D., Ph.D.
Assistant Professor of Medicine (Cardiovascular Medicine)
Current Research and Scholarly InterestsThe Weldy Lab studies how human genetic variation drives vascular dysfunction, inflammation, and cardiovascular disease. We integrate human genetics, epigenetics, single-cell genomics, RNA biology, and experimental models to define causal mechanisms and identify new therapeutic opportunities.
Led by Chad S. Weldy, MD, PhD, the lab focuses on questions at the intersection of cardiovascular genetics, vascular biology, and RNA-mediated regulation, with particular interest in smooth muscle cell phenotypic modulation, innate immune signaling, and mechanisms of disease susceptibility governed by epigenetic memory.
Our work is grounded in the idea that genetic discovery can do more than identify risk. It can reveal the biology that matters most and point toward more precise strategies for prevention and treatment.
https://weldylab.org/ -
Gerlinde Wernig
Associate Professor of Pathology
Current Research and Scholarly InterestsFibrotic diseases kill more people than cancer in this country and worldwide. We believe that scar-forming cells called fibroblasts are at the core of the fibrotic response in parenchymal organ fibrosis in the lung, liver, skin, bone marrow and tumor stroma. At the cellular level we think of fibrosis as a step wise process which implicates inflammation and fibrosis. We seek to identify new effective immune therapy targets to treat fibrotic diseases.
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Marius Wernig
Professor of Pathology and, by courtesy, of Chemical and Systems Biology
Current Research and Scholarly InterestsEpigenetic Reprogramming, Direct conversion of fibroblasts into neurons, Pluripotent Stem Cells, Neural Differentiation: implications in development and regenerative medicine
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Cornelia Weyand
Professor of Medicine (Immunology and Rheumatology), Emerita
Current Research and Scholarly InterestsAutoimmunity
Chronic inflammatory disease
Metabolic control of immune function -
Matthew T. Wheeler
Associate Professor of Medicine (Cardiovascular Medicine)
Current Research and Scholarly InterestsTranslational research in rare and undiagnosed diseases. Basic and clinical research in cardiomyopathy genetics, mechanisms, screening, and treatment. Investigating novel agents for treatment of hypertrophic cardiomyopathy and new mechanisms in heart failure. Cardiovascular screening and genetics in competitive athletes, disease gene discovery in cardiomyopathy and rare disease. Informatics approaches to rare disease and multiomics. Molecular transducers of physical activity bioinformatics.
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Jeffrey J. Wine
Benjamin Scott Crocker Professor of Human Biology, Emeritus
Current Research and Scholarly InterestsThe goal is to understand how a defective ion channel leads to the human genetic disease cystic fibrosis. Studies of ion channels and ion transport involved in gland fluid transport. Methods include SSCP mutation detection and DNA sequencing, protein analysis, patch-clamp recording, ion-selective microelectrodes, electrophysiological analyses of transmembrane ion flows, isotopic metho
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Virginia D. Winn, MD, PhD
Professor of Obstetrics and Gynecology (Reproductive, Perinatal & Stem Cell Biology Research)
Current Research and Scholarly InterestsThe Winn Laboratory seeks to understand the unique biological mechanisms of human placentation. While the placenta itself is one of the key characteristics for defining mammals, the human placenta is different from most available animal models: it is one of the most invasive placentas, and results in the formation of an organ comprised of cells from both the fetus and the mother. In addition to this fascinating chimerism, fetal cells are deeply involved in the remodeling of the maternal vasculature in order to redirect large volumes of maternal blood to the placenta to support the developing fetus. As such, the investigation of this human organ covers a large array of biological processes, and deals not only with understanding its endocrine function, but the physiologic process of immune tolerance, vascular remodeling, and cellular invasion.
