Stanford University
Showing 1-4 of 4 Results
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Dhriti Nagar
Postdoctoral Scholar, Neonatal and Developmental Medicine
BioPremature birth is a leading cause of developmental and neuropsychiatric disorders in children. One of the factors causing these defects is lowered levels of available oxygen (hypoxia) in the newborn due to immature lungs. My research focuses on understanding the cellular and molecular mechanisms underlying hypoxia-induced developmental disorders of the nervous system due to preterm birth.
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Michitaka Nakano
Postdoctoral Scholar, Hematology
BioI am a MD/PhD postdoctoral fellow and medical oncologist with a long-standing interest in translational cancer research. My long-term goal is to be a lab-based physician-scientist and independent academic researcher, translating basic cancer research, and mentoring next-generation scientists. My thesis work in Japan focused on cancer stem cell equilibrium by uniquely applying organoid culture as a method to elucidate cancer stem cell dynamics, which was awarded in Japanese Cancer Association. Along with the development of the field represented by success in T cell checkpoint, my interest gradually shifted to immune oncology while I examined numerous numbers of cancer patients as a medical oncology fellow. My postdoctoral fellowship at Calvin Kuo Lab in Stanford (2019-present) focuses on tumor immune microenvironment. Kuo lab developed a unique 3D air-liquid interface (ALI) organoid system that cultures tumors while preserving their endogenous infiltrating immune cells (T,B ,NK, Myeloid cells). My postdoctoral work will prove the significance of organoids as a translational tool to discover tumor-immune interaction by novel checkpoint inhibitors for immune cells, which can be broadly applicable to basic cancer biology, precision medicine, therapeutics validation and biomarker discovery.
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Kouta Niizuma
Basic Life Research Scientist, Stem Cell Bio Regenerative Med Institute
BioI am a Research Scientist in Prof. Hiromitsu Nakauchi's laboratory at Stanford University. I obtained my PhD in Immunology from the University of Tsukuba, Japan. During my doctoral studies in Prof. Akira Shibuya's laboratory, I focused on the characterization of cell surface receptors expressed on immune cells. I successfully cloned a novel human immunoglobulin-like receptor, CD300H, and established a specific monoclonal antibody. My research demonstrated that CD300H is expressed on a subset of human monocytes and dendritic cells and plays a crucial role in enhancing inflammation by promoting the production of inflammatory cytokines and chemokines.
During my PhD, I also studied as a visiting scholar in Prof. Lewis L. Lanier's laboratory at UCSF, where I investigated the role of the activating receptor NKG2D on NK cells in viral immunity.
Since May 2018, I have been a member of the Nakauchi lab. My current research focuses on the development of new immunotherapies using myeloid cells derived from iPS cells, the generation of monoclonal antibodies, and hematopoietic stem cell biology.
