Stanford University
Showing 131-140 of 149 Results
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Adrian Hugenmatter
Director of Protein Engineering
BioDr. Adrian Hugenmatter joined ChEM-H as Director of Protein Engineering in 2021. In his role, Dr. Hugenmatter heads the Protein Engineering Laboratory at the Nucleus and is responsible for the development of therapeutic proteins at the Innovative Medicines Accelerator (IMA). Dr. Hugenmatter obtained his PhD in the laboratory of Prof. Donald Hilvert at the Swiss Federal Institute of Technology in Zurich (ETH Zurich, Switzerland), where he gained initial experience in the fields of enzymology, antibody engineering and directed evolution. Fascinated by protein engineering, he moved to the laboratory of Prof. Dan Tawfik at the Weizmann Institute of Science (Israel), where he studied molecular evolution and its application in protein design. Dr. Hugenmatter then worked for more than a decade as a researcher and team leader at Roche. During this time, he was involved in the development and optimization of several antibody lead candidates for therapeutic applications in neuroscience and oncology.
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John Huguenard
Professor of Neurology and Neurological Sciences (Neurology Research), of Neurosurgery (Adult Neurosurgery) and, by courtesy, of Molecular and Cellular Physiology
On Leave from 02/16/2025 To 02/15/2026Current Research and Scholarly InterestsWe are interested in the neuronal mechanisms that underlie synchronous oscillatory activity in the thalamus, cortex and the massively interconnected thalamocortical system. Such oscillations are related to cognitive processes, normal sleep activities and certain forms of epilepsy. Our approach is an analysis of the discrete components (cells, synapses, microcircuits) that make up thalamic and cortical circuits, and reconstitution of components into in silico computational networks.
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Keith Humphreys
Esther Ting Memorial Professor and Professor, by courtesy, of Health Policy
Current Research and Scholarly InterestsDr. Humphreys researches individual and societal level interventions for addictive and psychiatric disorders. He focuses particularly on evaluating the outcomes of professionally-administered treatments and peer-operated self-help groups (e.g., Alcoholics Anonymous), and, analyzing the impact of public policies touching addiction, mental health, public health, and public safety.
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Paul S Humphries
Alliance Director, Innovative Medicines Accelerator (IMA)
Current Role at StanfordAlliance Director, Stanford Innovative Medicines Accelerator (IMA)
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Sohail Z Husain
Chambers-Okamura Endowed Professor of Pediatric Gastroenterology
Current Research and Scholarly InterestsMy research delves into three broad areas of the exocrine pancreas: (1) The crucial signaling pathways that initiate and transduce pancreatitis; (2) the factors that turn on pancreatic regeneration and recovery after pancreatic injury; and (3) the mechanisms underlying drug-induced pancreatitis.
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Natasha Hussain
Affiliate, Initiative in Brain Resilience
BioAs Associate Director of the Knight Initiative for Brain Resilience at Stanford University, Natasha Hussain plays a pivotal role in guiding the strategic direction of the initiative. In this capacity, she is responsible for conceptualizing and implementing transformative initiatives, overseeing program operations, and fostering a collaborative environment that integrates community engagement with cutting-edge research. Natasha's leadership encompasses a broad spectrum of responsibilities aimed at advancing the initiative's mission of supporting human brain function, health, and longevity. Her commitment to excellence and strategic innovation contributes to the initiative's position at the forefront of neuroscientific research and community impact.
Natasha received a B.Sc. from McGill University in Montreal, QC, Canada where she completed a double major in biology and environmental science. Natasha continued in her doctoral training at McGill University’s Montreal Neurological Institute at where she earned a Ph.D. in Neurology and Neurosurgery. Natasha's expertise in biochemistry, molecular and cell biology has contributed to significant discoveries in neuroscience, focusing on presynaptic endocytic recycling, Rho GTPases-mediated signal transduction, and the functional characterization of proteins linked to Down’s syndrome and Alzheimer’s disease neuropathology.
During her postdoctoral training at MIT in the Picower Institute for Learning and Memory, Cambridge, MA, USA, Natasha delved into molecular components of synaptic plasticity. Her research also explored the cell biology and physiology of a family of protein kinases genetically associated with psychiatric disorders, unraveling their roles in synapse development and function.
Prior to her role at the Knight Initiative, Natasha served as the Scientific Director of the Johns Hopkins Kavli Neuroscience Discovery Institute, fostering transdisciplinary research collaboration among neuroscientists, engineers, and data scientists. -
Ruth Huttenhain
Assistant Professor of Molecular and Cellular Physiology
Current Research and Scholarly InterestsMy group deciphers how G protein-coupled receptors decode extracellular cues into dynamic and context-specific cellular signaling networks to elicit diverse physiologic responses. We exploit quantitative proteomics to capture the spatiotemporal organization of signaling networks combined with functional genomics to study their impact on physiology.
