Stanford University
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Rebecca Pinals
Assistant Professor of Chemical Engineering
BioThe brain is a fascinatingly complex and delicate system of biomolecules, cells, and dynamic interactions that must be carefully maintained to support human health. When this balance is disrupted, disease can arise. Neurodegenerative dementias including Alzheimer’s disease are highly prevalent and profoundly devastating, yet remain largely untreatable or incurable.
The Pinals Lab engineers neuro-models and nano-tools to uncover mechanisms of neurodegenerative disease and intervene to halt—and even reverse—disease progression. A particular emphasis of our work is on the blood–brain barrier (BBB), the vascular interface that serves as the molecular gateway into the brain. We leverage human induced pluripotent stem cells (iPSCs) to build 3D cellular systems, providing a platform to recapitulate human brain properties and pathologies. In parallel, we design nanoparticles to report on real-time neurochemical processes, enabling unprecedented access to dynamic and spatially resolved biomolecular phenomena, and to modulate disease states. By integrating advanced human brain tissue models with rationally designed nanotechnologies, we aim to generate fundamental insights and tools that translate into meaningful impacts for human health. -
Lisa Pineda
Senior Simulations Specialist, Pediatrics - Neonatology
BioLisa received a Bachelor of Science in Kinesiology with an emphasis in Athletic Training from San Jose State University, a Master of Science in Perinatal Clinical Nurse Specialist/Neonatal Emphasis from the University of California San Francisco, and a Post-Graduate Family Nurse Practitioner Certificate from San Francisco State University.
Lisa started her nursing career at Lucile Packard Children’s Hospital in the Labor and Delivery Unit. It became clear early in her career that research-driven high-quality patient-centered care was integral to her learning and passion for nursing. As a staff nurse, she participated in multiple obstetric simulations at CAPE, and she was immediately drawn to the systematic approach, clear communication, and debriefing process within the simulation methodology. For more than two decades, Lisa’s work has included bedside nursing, advanced practice nursing for women and children, and public health nursing with a particular passion for research dedicated to improving patient outcomes.
