Stanford University
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Lynette Cegelski
Monroe E. Spaght Professor of Chemistry and Professor, by courtesy, of Chemical Engineering
Current Research and Scholarly InterestsResearch in the Cegelski laboratory is driven by the need to uncover and define the chemistry that underlies outstanding challenges in human health, the environment, and sustainability. Beyond discovery, we use chemistry as a tool to innovate and create solutions to these pressing problems. The laboratory is highly interdisciplinary, designing experimental approaches to understand how complex biological systems are built, organized, and controlled, and then perturb and influence assembly processes. The lab develops new methods and uniquely leverages: (1) small molecules in new biochemical assay development, chemical genetics approaches, and therapeutic discovery in infectious diseases, (2) fluorescence and electron microscopy coupled to analytical HPLC, mass spectrometry, and complementary biochemical techniques, and (3) spectroscopy, particularly solid-state NMR, to uncover new “dark matter” and define chemistry in insoluble, heterogeneous and complex assemblies relevant to human health, plants, and the ocean.
Long-standing efforts in the laboratory focus on defining mechanisms underlying bacterial biofilm formation and identifying new antibiotic and anti-virulence strategies, including advancing therapeutic candidates for the most difficult-to-treat infections. Through these efforts, we uncovered a new chemical structure in nature: phosphoethanolamine (pEtN) cellulose. Cellulose is the most abundant biopolymer on earth and this discovery provided the first experimental validation of a naturally produced chemically modified cellulose. We are developing alternatively modified celluloses and polysaccharides and advancing new solutions for ecofriendly, sustainably sourced, and recyclable materials. Collectively, our projects span disciplines from molecular structure and assembly chemistry to living microbial communities and natural marine systems, while aiming to translate fundamental discoveries into therapeutic and materials solutions. -
Carlos Centeno Lairet
Affiliate, Ethics In Society
BioCarlos is a 2026 Ethics & Tech Practitioner Fellow at the McCoy Family Center for Ethics in Society. He co-founded SOMOS Civic Lab. At the lab, the team is researching and designing tools to democratize generative AI in Global Majority countries. Somos is part of the UNDP AI Trust & Safety Programme, and it's supported by the Pulitzer Center's AI Accountability program. As MIT Emerging Talent Director, he equips learners from migrant and refugee communities with computer science skills. He co-founded and directed MIT's Governance Innovation Initiative, as Associate Director of Innovation; co-designed and launched MIT's first Governance Innovation Research Fellowship, and hosted MIT's "Power to the Who" governance innovation podcast. He was previously at the UN for 10 years, where he worked in community and government preparedness to natural disasters based in Latin America, Asia and Africa. His AI (NLP) prototype ALIA was a Google launchpad finalist in Munich (2018). He has supported investigative journalism projects at Pro Publica on disappearances and detentions by the US federal government.
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Giovanna Ceserani
Professor of Classics
Current Research and Scholarly InterestsIntellectual history, data science in the humanities, ancient and modern historiography, history of archaeology, early modern travels and explorations of the past
