Stanford University
Showing 21-30 of 228 Results
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Pauline Brochet
Postdoctoral Scholar, Cardiovascular Medicine
BioPauline Brochet is a French scientist from Souraide, France. She completed her undergraduate studies in Molecular, Cellular and Physiological Biology (BSc, Université Clermont-Auvergne) and earned a Master's degree in Software Development and Data Analysis (MSc, Aix-Marseille Université). Pauline pursued a PhD at TAGC (Theories and Approaches for Genomic Complexity) in Marseille, France.
Under the supervision of Dr. Christophe Chevillard and Dr. Lionel Spinelli, Pauline integrated multi-omics data from human heart tissue to investigate the pathogenic processes associated with Chagas Disease Cardiomyopathy (CCC). Notably, she contributed to the development of ChagasDB, the first database associating key features with the different stages of Chagas disease. Her research identified the involvement of mitochondrial DNA mutations, non-coding RNA, transcription factors, and DNA methylation in various pathogenic processes, all leading to the progression of CCC.
Currently, at Stanford University, under the guidance of Dr. Matthew Wheeler and Dr. Daniel Katz, Pauline is conducting postdoctoral research on multi-omics data analysis as part of the Molecular Transducers of Physical Activity Consortium (MoTrPAC). Her work focuses on identifying key covariable features associated with physical exercise, with the ultimate goal of discovering exercise-mimetic drugs that could help prevent heart diseases. -
Cristina Cadenas Sanchez
Visiting Postdoctoral Scholar, Medicine - Med/Cardiovascular Medicine
BioDr. Cadenas-Sanchez is a Marie Curie postdoctoral fellow at Stanford University and at the Palo Alto VA Health Care System. Her research is focused on: i) the effect of exercise program on brain and physical health in children with obesity; ii) the effect of exercise on different fat depots (intermuscular, pancreatic, visceral, subcutaneous, and hepatic fat) in children with obesity; and iii) the cancer and non-communicable disease prevention through physical fitness/physical activity. She is currently running as principal investigator the PreCaFit (Prevention Cancer through physical fitness, European Union-funded) project which examines the relationship between fitness, physical activity and cancer. Further, to ensure the scalability of the results, PreCaFit project will examine the effects of exercise on cancer biomarkers.
She earned her bachelor's, master's and doctorate's degree from the University of Granada (Spain). She has more than 100 scientific articles (indexed in Journal Citation report), and several books and book-chapters published. Some of the articles have been published in high-impact journals (JAMA Network Open, Diabetes Care, Sports Medicine, Journal of Hepatology, etc.), of which four are/have been considered as highly cited papers (Thomson Reuters). She is recognized as a worldwide expert (among top-15) on physical fitness and cardiorespiratory fitness by ExpertScape. She was also selected as one of the most highlighted Spanish women researcher (including non-Spanish women but working in a Spanish institution) by the Spanish National Research Council. Also, she has received several awards as best young researcher. -
Stephen Chang, MD, PhD
Instructor, Biochemistry
Instructor, Medicine - Cardiovascular MedicineBioPrior to a career in medicine, Dr. Chang was an English major and subsequent novelist at night. During the days, he taught literature part-time at Rutgers University, and for extra money, worked in a laboratory in NYC washing test tubes. Inspired by his laboratory mentor, he began volunteering at the hospital next door, and developed a love for interacting with patients. Through this experience, he saw how caring for others could form deep bonds between people - even strangers - and connect us in a way that brings grandeur to ordinary life.
In addition to seeing patients, Dr. Chang is a physician-scientist devoted to advancing the field of cardiovascular medicine. His research has been focused on identifying a new genetic organism that better models human heart disease than the mouse. For this purpose, he has been studying the mouse lemur, the smallest non-human primate, performing cardiovascular phenotyping (vital signs, ECG, echocardiogram) on lemurs both in-bred (in France) and in the wild (in Madagascar) to try to identify mutant cardiac traits that may be heritable - and in the process, characterize the first high-throughput primate model of human cardiac disease. -
Ming Li (Estella) Chen
Postdoctoral Scholar, Cardiovascular Medicine
BioI am an MD from Chung Shan Medical University, Taiwan. Before coming to Stanford, I obtained my MS degree in epidemiology at Harvard T.H. Chan School of Public Health, Boston, MA, where I completed graduate training in clinical, pharmacologic, and genetic epidemiology, and pursued advanced skills in biostatistics and causal inference.
My past research focused on real-world epidemiology studies using patient registries and national health insurance databases to elucidate the predictors or risk factors of immunologic diseases. For my graduate study, I conducted pharmacoepidemiology studies using electronic health record (EHR) data to elucidate the predictors of anti-drug antibodies development and its correlation to autoimmunity, to identify the generation of immunogenicity that may impact the effectiveness of monoclonal antibody therapies in individuals with autoimmune diseases. I gained experience in genetic data manipulation to investigate polymorphisms in response to monoclonal antibody therapies in asthma patients.
At Stanford, I am involved in research on the identification of molecular determinants of cardiometabolic diseases. -
Paul Cheng MD PhD
Assistant Professor of Medicine (Cardiovascular Medicine)
BioDr. Cheng is a Cardiologist at Stanford University School of Medicine in the Department of Medicine and a member of the Cardiovascular Research Institute. Dr. Cheng received his BEng in Chemical Engineering and BSc in biology at MIT. He subsequently completed his MD/PhD at UCSF working in the Srivastava lab studying how extracellular morphogenic signals affect cardiac development and fate determination of cardiac progenitors. Dr. Cheng completed internal medicine residency and cardiology fellowship at Stanford. His current clinical focus is in amyloidosis and cardio-oncology. During his post doctoral research in the Quertermous lab, he pioneered the application of single cell transcriptomic and epigenetic techniques to study human vascular diseases including atherosclerosis and aneurysm, and applied these techniques to investigate molecular mechanisms behind genetic risk factors for several human vascular diseases including atherosclerosis, and aortopathies such as Marfan's and Loey-Dietz syndrome.
The Cheng lab takes a patient-to-bench-to-bedside approach to science. The lab focuses on elucidating new pathogenic mechanisms of human vascular diseases through combing human genetics and primary vascular disease tissues, with high-resolution transcriptomic and epigenetic profiling to generate novel hypothesis that are then tested in a variety of in vitro and in vivo models. The lab is focused on two broad questions: (1) understanding the biological underpinning of the differences in diseases propensities of different arterial segments in an individual (i.e. why do you have atherosclerosis and aneurysms in certain segments but not others), and (2) understanding the role of perivascular fibroblast in human vascular diseases.
Find out more about what the Cheng lab is up to, check out https://chenglab.stanford.edu
