Stanford University
Showing 81-90 of 344 Results
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Paul Graham Fisher, MD
Beirne Family Professor of Pediatric Neuro-Oncology, Professor of Pediatrics and, by courtesy, of Neurosurgery and of Epidemiology and Population Health
Current Research and Scholarly InterestsClinical neuro-oncology: My research explores the epidemiology, natural history, and disease patterns of brain tumors and other cancers in childhood, as well as prospective clinical trials for treating these neoplasms. Research interests also include neurologic effects of cancer and its therapies.
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Robert Fisher, MD, PhD
The Maslah Saul, MD, Professor and Professor, by courtesy, of Neurosurgery
Current Research and Scholarly InterestsDr. Fisher is interested in clincal, laboratory and translational aspects of epilepsy research. Prior work has included: electrical deep brain stimulation for epilepsy, studied in laboratory models and clinical trials; drug delivery to a seizure focus; mechanisms of absence epilepsy studied with in vitro slices of brain thalamus; hyperthermic seizures; diagnosis and treatment of non-epileptic seizures, the post-ictal state; driving and epilepsy; new antiepileptic drugs; surgery for epilepsy.
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Paul George, MD, PhD
Associate Professor of Neurology and Neurological Sciences (Adult Neurology) and, by courtesy, of Neurosurgery
Current Research and Scholarly InterestsDEVELOPMENT OF STROKE RECOVERY THERAPEUTICS:
Stroke is devastating to patients and their caregivers. We currently are investigating 3 neural repair approaches. The first focuses on developing a stroke recovery therapeutic based on an essential repair pathway and how it alters the immune response following stroke. The second utilizes implantable, conductive polymer devices to electrically manipulate the recovering nervous system to improve recovery and identify novel therapeutic targets. The final approach works to optimize stem cell therapeutics to enhance their ability to treat patients who have suffered from neural injury.
CONDUCTIVE BIOPOLYMER SYSTEMS FOR NEURAL RECOVERY AND STEM CELL MODULATION:
The George lab develops biomaterials to improve neural recovery in the peripheral and central nervous systems. By controlled release of drugs and molecules through biomaterials we can study the temporal effect of these neurotrophic factors on neural recovery and engineer drug delivery systems to enhance regenerative effects. By identifying the critical mechanisms for neural recovery, we are able to develop polymeric technologies for clinical translation in nerve regeneration. Recent work utilizes these novel conductive polymers to differentiate stem cells for therapeutic and drug discovery applications.
APPLYING ENGINEERING TECHNIQUES TO DETERMINE BIOMARKERS FOR STROKE DIAGNOSTICS:
The ability to create diagnostic assays and techniques enables us to understand biological systems more completely and improve clinical management. Previous work utilized mass spectroscopy proteomics to find a simple serum biomarker for TIAs (a warning sign of stroke). Our study discovered a novel candidate marker, platelet basic protein. Current studies are underway to identify further candidate biomarkers using transcriptome analysis. More accurate diagnosis will allow for aggressive therapies to prevent subsequent strokes. -
Pejman Ghanouni, MD, PhD
Professor of Radiology (Body MRI) and, by courtesy, of Neurosurgery, of Obstetrics and Gynecology and of Urology
BioDr. Ghanouni is a board-certified, fellowship-trained diagnostic radiologist with Stanford Health Care Radiology. He is an associate professor in the Department of Radiology, Division of Body MRI at Stanford University School of Medicine, and by courtesy, of Urology, of Neurosurgery, and of Obstetrics and Gynecology.
Dr. Ghanouni is the director of the Stanford Health Care Minimally Invasive MR Interventional Center (MIMRIC) and the Focused Ultrasound Center of Excellence. He is also chief of the Division of Body MRI at Stanford University School of Medicine.
Dr. Ghanouni is recognized around the world for his extensive expertise in using advanced imaging to diagnose, manage, and treat a wide range of conditions and disorders. As a renowned leader in diagnostic and MRI-guided interventional radiology, Dr. Ghanouni creates a customized care plan for each of his patients.
Dr. Ghanouni’s research interests include the latest advances in MR-guided focused ultrasound techniques to treat essential tremor, Parkinson’s disease, prostate cancer, bone tumors, desmoid tumors, and uterine fibroids. An experienced physician-scientist, Dr. Ghanouni has collaboratively led clinical trials and research initiatives that explore treatments for epilepsy, pancreatic cancer, and several types of tumors. Through these clinical trials, Dr. Ghanouni has helped secure FDA approval for many MR-guided focused ultrasound treatments.
His articles have been published in dozens of peer-reviewed medical journals, including Lancet Oncology, Neurology, Investigative Radiology, European Radiology, Journal of Magnetic Resonance Imaging, Journal of Neurosurgery, New England Journal of Medicine, and Radiology. Dr. Ghanouni has been invited to speak at conferences and symposiums all over the nation and the world, including in Rome, Italy; Tel Aviv, Israel; and Riyadh, Saudi Arabia. He is widely regarded for his groundbreaking research as well as his clinical expertise.
Dr. Ghanouni is a member of several professional organizations, including the International Society for Magnetic Resonance in Medicine, the International Society for Therapeutic Ultrasound, and the European Focused Ultrasound Society.
MR-guided focused ultrasound treatment: https://www.youtube.com/watch?v=3Bwq2YxD9eU -
Iris C. Gibbs, MD, FACR, FASTRO
Professor of Radiation Oncology (Radiation Therapy) and, by courtesy, of Neurosurgery
Current Research and Scholarly InterestsDr. Gibbs is a board-certified radiation oncologist who specializes in the treatment of CNS tumors. Her research focuses on developing new radiation techniques to manage brain and spinal tumors in adults and children. Dr. Gibbs has gained worldwide acclaim for her expertise in Cyberknife robotic radiosurgery.
