Stanford University
Showing 12,891-12,900 of 36,305 Results
-
Seth Ari Sim-Son Hoffman
Instructor, Medicine - Infectious Diseases
Current Research and Scholarly InterestsClinical research to benefit underserved populations.
-
Florian Hoffmann, Ph.D.
Postdoctoral Scholar, Hematology
BioFlorian is a postdoctoral researcher in Dr. Ami Bhatt's laboratory at Stanford University. He earned his Ph.D. in Biochemistry working in Dr. Sam Sternberg's group at Columbia University where he studied atypical CRISPR systems in prokaryotes, in search of molecular tools for programmable gene editing and gene regulation. His studies elucidate the mechanisms of a novel RNA-guided transposition system, the evolutionary ancestors of the gene editing enzymes Cas9 and Cas12, and an unprecedented Cas12f enzyme that creates custom de novo transcription start sites without requiring promoter elements. Florian is fascinated by the vast untapped resources of novel gene functions encoded in bacteria and their viruses (bacteriophages). He is an inventor on multiple patents related to his doctoral work. During his postdoctoral work at Stanford, he aims to discover novel paradigms of bacteria-virus interactions and how these shape the human gut microbiome, and human health. To investigate these systems, he harnesses interdisciplinary approaches, combining computational gene discovery with experimental techniques in Molecular Biology, Genetics and Biochemistry.
