Wu Tsai Neurosciences Institute
Showing 631-640 of 645 Results
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Jerome Yesavage
Jared and Mae Tinklenberg Professor and Professor, by courtesy, of Neurology and Neurological Sciences
Current Research and Scholarly InterestsWe study cognitive processes and aging in our research center. Studies range from molecular biology to neuropsychology of cognitive processes.
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Serena Yeung-Levy
Assistant Professor of Biomedical Data Science and, by courtesy, of Electrical Engineering and of Computer Science
BioDr. Serena Yeung-Levy is an Assistant Professor of Biomedical Data Science and, by courtesy, of Computer Science and of Electrical Engineering at Stanford University. Her research focus is on developing artificial intelligence and machine learning algorithms to enable new capabilities in biomedicine and healthcare. She has extensive expertise in deep learning and computer vision, and has developed computer vision algorithms for analyzing diverse types of visual data ranging from video capture of human behavior, to medical images and cell microscopy images.
Dr. Yeung-Levy leads the Medical AI and Computer Vision Lab at Stanford. She is affiliated with the Stanford Artificial Intelligence Laboratory, the Clinical Excellence Research Center, and the Center for Artificial Intelligence in Medicine & Imaging. She is also a Chan Zuckerberg Biohub Investigator and has served on the NIH Advisory Committee to the Director Working Group on Artificial Intelligence. -
Jong H. Yoon
Professor of Psychiatry and Behavioral Sciences (Public Mental Health & Population Sciences)
Current Research and Scholarly InterestsMy research seeks to discover the brain mechanisms responsible for schizophrenia and to translate this knowledge into the clinic to improve how we diagnose and treat this condition. Towards these ends, our group has been developing cutting-edge neuroimaging tools to identify neurobiological abnormalities and test novel systems-level disease models of psychosis and schizophrenia directly in individuals with these conditions.
We have been particularly interested in the role of neocortical-basal ganglia circuit dysfunction. A working hypothesis is that some of the core symptoms of schizophrenia are attributable to impairments in neocortical function that results in disconnectivity with components of the basal ganglia and dysregulation of their activity. The Yoon Lab has developed new high-resolution functional magnetic resonance imaging methods to more precisely measure the function of basal ganglia components, which given their small size and location deep within the brain has been challenging. This includes ways to measure the activity of nuclei that store and control the release of dopamine throughout the brain, a neurochemical that is one of the most important factors in the production of psychosis in schizophrenia and other neuropsychiatric conditions. -
Kyan Younes, MD
Clinical Assistant Professor, Adult Neurology
BioDr. Younes is a fellowship-trained, board-certified neurologist and a clinical assistant professor in the Department of Neurology at Stanford University School of Medicine.
His areas of expertise include the diagnosis and treatment of Alzheimer’s disease, frontotemporal dementia, primary progressive aphasia, Lewy body dementia, normal pressure hydrocephalus and cognitive and behavioral impairments. For each patient, Dr. Younes develops a personalized plan of care. A plan may include his close collaboration with experts from psychiatry, nursing, pharmacy, genetic counseling, and other specialties. His goal is to ensure that each patient receives care that is both comprehensive and compassionate.
To help lead advances and innovations in his field, Dr. Younes conducts extensive research. He is studying the clinical, neuropsychological, socioemotional, genetic, and pathological features when a patient experiences degeneration of the right anterior temporal lobe area of the brain. This disorder can affect a person’s ability to process emotions and person-specific knowledge.
He also is researching how multimodal brain imaging, including magnetic resonance imaging (MRI) and Positron Emission Tomography (PET) combined with machine learning can help improve the detection of neurodegenerative diseases. In other research, he has participated in clinical trials of new drug therapies for Alzheimer’s disease.
Dr. Younes has presented research findings at meetings of the American Neurological Association, American Academy of Neurology, and American Psychiatric Association. Topics have included predictors of cognitive performance in dementia.
He has co-authored research articles published in the American Journal of Psychiatry, Annals of Clinical and Translational Neurology, Journal of Neuroimaging, and elsewhere. Subjects of these articles have included guidelines for diagnosing the effects of right anterior temporal lobe degeneration on behavior, treatment for symptoms of encephalitis, and the impact of mild traumatic brain injury on healthy older adults.
Dr. Younes has written chapters on frontotemporal dementia for Psychiatric Clinics as well as the epilepsy, coma, acute ischemic stroke, meningitis and encephalitis chapters for the textbook The Little Black Book of Neurology.
He is a member of the American Academy of Neurology, American Neurological Association, Alzheimer’s Association, and International Society for Frontotemporal Dementias. -
Hengameh Zahed, MD, PhD
Clinical Assistant Professor, Adult Neurology
BioDr. Zahed is a board-certified, fellowship-trained neurologist with the Stanford Medicine Movement Disorders Center. She is also a clinical assistant professor in the Department of Neurology and Neurological Sciences.
She diagnoses and treats a wide range of movement disorders including Parkinson’s disease, Huntington’s disease, essential tremor, dystonia, and ataxia. She creates a personalized treatment plan for each of her patients using a variety of treatment options, including pharmacological and non-pharmacological options, deep brain stimulation (DBS) treatment for Parkinson's disease and tremors, and botulinum toxin injections for movement disorders and spasticity.
Prior to joining Stanford University, Dr. Zahed completed a neurology residency and fellowship in movement disorders at University of California, San Francisco (UCSF), where she also earned her MD and PhD in biomedical sciences. Dr. Zahed’s research interests include understanding the genetic and electrophysiological underpinnings of movement disorders and investigating applications of wearable technologies to monitor symptoms and improve the quality of life in patients with movement disorders. She also participates in clinical trials of new therapeutics for Parkinson’s disease and other movement disorders.
Dr. Zahed has published in Movement Disorders, Molecular Genetics & Genomic Medicine, The Journal of Clinical Investigation, American Journal of Human Genetics, Cell, and other peer-reviewed journals. She has presented to her peers at international, national, and regional meetings. These meetings have included the International Congress of Parkinson’s Disease and Movement Disorders, the Hereditary Disease Foundation Symposium, the World Society for Stereotactic and Functional Neurosurgery, and the Society for Neuroscience.
Dr. Zahed is a member of the International Parkinson and Movement Disorders Society. -
Natalie M. Zahr
Assistant Professor (Research) of Psychiatry and Behavioral Sciences (Major Laboratories)
BioNatalie M. Zahr received a graduate education in the basic sciences including the study of neuro- pharmacology, physiology, and anatomy. After completing her graduate training in electrophysiology, she began a postdoctoral fellowship as a magnetic resonance imaging (MRI) scientist. Her work focuses on translational approaches using in vivo MR imaging and spectroscopy in studies of human with Alcohol Use Disorders (AUD) and in rodent models of alcohol exposure with the goal of identifying mechanisms of alcohol effects on the brain. Her human studies include participants with HIV, those co-morbid for HIV and AUD and recently, aging individuals with mild cognitive impairment (MCI). Her position allows her to explore emerging MR technologies and apply them to test relevant hypotheses. Before joining Stanford, she taught at several local institutions including UC Berkeley extension and Santa Clara University where she enjoyed sharing her knowledge and enthusiasm for learning with students.
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Jamil Zaki
Professor of Psychology
Current Research and Scholarly InterestsMy research focuses on the cognitive and neural bases of social behavior, and in particular on how people respond to each other's emotions (empathy), why they conform to each other (social influence), and why they choose to help each other (prosociality).
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Richard Zare
Marguerite Blake Wilbur Professor of Natural Science and Professor, by courtesy, of Physics
Current Research and Scholarly InterestsMy research group is exploring a variety of topics that range from the basic understanding of chemical reaction dynamics to the nature of the chemical contents of single cells.
Under thermal conditions nature seems to hide the details of how elementary reactions occur through a series of averages over reagent velocity, internal energy, impact parameter, and orientation. To discover the effects of these variables on reactivity, it is necessary to carry out studies of chemical reactions far from equilibrium in which the states of the reactants are more sharply restricted and can be varied in a controlled manner. My research group is attempting to meet this tough experimental challenge through a number of laser techniques that prepare reactants in specific quantum states and probe the quantum state distributions of the resulting products. It is our belief that such state-to-state information gives the deepest insight into the forces that operate in the breaking of old bonds and the making of new ones.
Space does not permit a full description of these projects, and I earnestly invite correspondence. The following examples are representative:
The simplest of all neutral bimolecular reactions is the exchange reaction H H2 -> H2 H. We are studying this system and various isotopic cousins using a tunable UV laser pulse to photodissociate HBr (DBr) and hence create fast H (D) atoms of known translational energy in the presence of H2 and/or D2 and using a laser multiphoton ionization time-of-flight mass spectrometer to detect the nascent molecular products in a quantum-state-specific manner by means of an imaging technique. It is expected that these product state distributions will provide a key test of the adequacy of various advanced theoretical schemes for modeling this reaction.
Analytical efforts involve the use of capillary zone electrophoresis, two-step laser desorption laser multiphoton ionization mass spectrometry, cavity ring-down spectroscopy, and Hadamard transform time-of-flight mass spectrometry. We believe these methods can revolutionize trace analysis, particularly of biomolecules in cells. -
Michael Zeineh
Professor of Radiology (Neuroimaging and Neurointervention)
BioDr. Michael Zeineh received a B.S. in Biology at Caltech in 1995 and obtained his M.D.-Ph.D. from UCLA in 2003. After internship also at UCLA, he went on to radiology residency and neuroradiology fellowship both at Stanford. He has been faculty in Stanford Neuroradiology since 2010. He spearheads many initiatives in advanced clinical imaging at Stanford, including clinical fMRI and DTI. Simultaneously, he runs a lab with the goal of discovering new imaging abnormalities in neurodegenerative disorders, with a focus on detailed microcircuitry in regions such as the hippocampal formation using advanced, multi-modal in vivo and ex vivo methods, with applications to neurodegenerative disorders such as Alzheimer’s disease and mild traumatic brain injury.
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Jamie Zeitzer
Professor (Research) of Psychiatry and Behavioral Sciences (Sleep Medicine)
Current Research and Scholarly InterestsDr. Zeitzer is a circadian physiologist specializing in the understanding of the impact of light on circadian rhythms and other aspects of non-image forming light perception.
He examines the manner in which humans respond to light and ways to manipulate this responsiveness, with direct application to jet lag, shift work, and altered sleep timing in teens. Dr. Zeitzer has also pioneered the use of actigraphy in the determination of epiphenomenal markers of psychiatric disorders.