Charles Michael Lombard
Clinical Professor, Pathology
Clinical Focus
- Anatomic and Clinical Pathology
Academic Appointments
-
Clinical Professor, Pathology
Professional Education
-
Residency: Santa Clara Valley Medical Center (1984) CA
-
Board Certification: American Board of Pathology, Clinical Pathology (1985)
-
Residency: Stanford University Pathology Residency (1983) CA
-
Board Certification: American Board of Pathology, Anatomic Pathology (1982)
-
Residency: Michael Reese Hospital and Med Ctr (1981) IL
-
Residency: Stanford University Pathology Residency (1980) CA
-
Medical Education: University of Chicago Hospitals (1978) IL
All Publications
-
Use of the Wireless Motility Capsule in the Diagnosis of Gastric Hypochlorhydria: pHinding Extra Value.
Digestive diseases and sciences
2020
View details for DOI 10.1007/s10620-020-06605-8
View details for PubMedID 32974808
-
Gastritis Cystica Polyposa: A Rare Cause of Abdominal Pain and Early Satiety Treated with Endoscopic Resection
DIGESTIVE DISEASES AND SCIENCES
2018; 63 (12): 3220–23
View details for PubMedID 29987627
-
Gastritis Cystica Polyposa: A Rare Case of Abdominal Pain and Satiety
NATURE PUBLISHING GROUP. 2018: S1461
View details for Web of Science ID 000464611005175
-
Sun Should Not Rise and Set on a Case of Acute Intestinal Obstruction.
Digestive diseases and sciences
2017
View details for DOI 10.1007/s10620-017-4612-0
View details for PubMedID 28500588
-
When It Rains It Pours: Evolving, Complicated Small Intestinal Crohn's Disease.
Digestive diseases and sciences
2017; 62 (3): 577-582
View details for DOI 10.1007/s10620-016-4444-3
View details for PubMedID 28058597
-
Double-Edged Sword: Esophageal and Colonic Crohn's Disease
DIGESTIVE DISEASES AND SCIENCES
2016; 61 (6): 1487-1490
View details for DOI 10.1007/s10620-015-3855-x
View details for Web of Science ID 000376587600013
View details for PubMedID 26320086
-
An Elusive Cause of Severe Gastrointestinal Bleeding
DIGESTIVE DISEASES AND SCIENCES
2014; 59 (1): 31-34
View details for DOI 10.1007/s10620-013-2838-z
View details for Web of Science ID 000330585500010
View details for PubMedID 23979438
-
Serous carcinoma of the ovary with squamous differentiation: a case report and a literature review.
International journal of gynecological pathology
2013; 32 (5): 459-463
Abstract
Serous carcinoma of the ovary showing squamous differentiation is a rarely reported neoplasm. We present 1 case of such a tumor extensively involving the adnexa and the pelvis, which shows these 2 intimately entwined, yet with morphologically and immunohistochemically distinct patterns of differentiation. We also report immunohistochemical evidence of protein expression changes in areas of this carcinoma that provide evidence for differentiation from a serous to a squamous phenotype.
View details for DOI 10.1097/PGP.0b013e31826f0327
View details for PubMedID 23896710
-
Esophageal Adenocarcinoma Presenting as Pseudo-Achalasia in a Patient with Juvenile Polyposis Syndrome: An Enemy Out of the Blue (vol 56, pg 1944, 2011)
DIGESTIVE DISEASES AND SCIENCES
2011; 56 (8): 2508
View details for DOI 10.1007/s10620-011-1627-9
View details for Web of Science ID 000293296100049
-
Esophageal Adenocarcinoma Presenting as Pseudo-Achalasia in a Patient with Juvenile Polyposis Syndrome: An Enemy Out of the Blue
DIGESTIVE DISEASES AND SCIENCES
2011; 56 (7): 1944-1948
View details for DOI 10.1007/s10620-011-1579-0
View details for Web of Science ID 000291481800005
View details for PubMedID 21267778
-
"War and Peace" with Barrett's Esophagus
DIGESTIVE DISEASES AND SCIENCES
2011; 56 (4): 988-992
View details for DOI 10.1007/s10620-010-1490-0
View details for Web of Science ID 000288512300008
View details for PubMedID 21161381
-
Multiple Rectal Polyps in a Young Woman with Constipation
DIGESTIVE DISEASES AND SCIENCES
2010; 55 (4): 890-894
View details for DOI 10.1007/s10620-010-1186-5
View details for Web of Science ID 000276153900004
View details for PubMedID 20221694
-
Reduction in airway hyperresponsiveness to methacholine by the application of RF energy in dogs.
Journal of applied physiology (Bethesda, Md. : 1985)
2004; 97 (5): 1946-53
Abstract
We delivered controlled radio frequency energy to the airways of anesthetized, ventilated dogs to examine the effect of this treatment on reducing airway narrowing caused by a known airway constrictor. The airways of 11 dogs were treated with a specially designed bronchial catheter in three of four lung regions. Treatments in each of the three treated lung regions were controlled to a different temperature (55, 65, and 75 degrees C); the untreated lung region served as a control. We measured airway responsiveness to local methacholine chloride (MCh) challenge before and after treatment and examined posttreatment histology to 3 yr. Treatments controlled to 65 degrees C as well as 75 degrees C persistently and significantly reduced airway responsiveness to local MCh challenge (P < or = 0.022). Airway responsiveness (mean percent decrease in airway diameter after MCh challenge) averaged from 6 mo to 3 yr posttreatment was 79 +/- 2.2% in control airways vs. 39 +/- 2.6% (P < or = 0.001) for airways treated at 65 degrees C, and 26 +/- 2.7% (P < or = 0.001) for airways treated at 75 degrees C. Treatment effects were confined to the airway wall and the immediate peribronchial region on histological examination. Airway responsiveness to local MCh challenge was inversely correlated to the extent of altered airway smooth muscle observed in histology (r = -0.54, P < 0.001). We conclude that the temperature-controlled application of radio frequency energy to the airways can reduce airway responsiveness to MCh for at least 3 yr in dogs by reducing airway smooth muscle contractility.
View details for DOI 10.1152/japplphysiol.01282.2003
View details for PubMedID 15258133
-
Reduction in airway hyperresponsiveness to methacholine by the application of RF energy in dogs
JOURNAL OF APPLIED PHYSIOLOGY
2004; 97 (5): 1946-1953
View details for DOI 10.1152/japplphysiol.01282.2003
View details for Web of Science ID 000224361700052
-
EXPRESSION OF CD34 BY SOLITARY FIBROUS TUMORS OF THE PLEURA, MEDIASTINUM, AND LUNG
AMERICAN JOURNAL OF SURGICAL PATHOLOGY
1994; 18 (8): 814-820
Abstract
Solitary fibrous tumors are rare neoplasms that most commonly involve the pleura, mediastinum, and lung. Because they lack distinctive histologic features, immunologic staining has frequently been employed to exclude other neoplasms in the differential diagnosis. Their reported phenotype to date is generally negative, notably for muscle-type actins, desmin, keratin, and S-100 protein. Although this testing is of some help, it does not serve to distinguish all processes in the differential diagnosis, and when it does, it places too great an emphasis on a negative finding to make a diagnosis. We report here that CD34 monoclonal antibodies reacted with 11 of 14 solitary fibrous tumors in paraffin sections. Thus, they provide a positive marker that distinguishes the solitary fibrous tumor from most elements in the differential diagnosis.
View details for Web of Science ID A1994NZ05000008
View details for PubMedID 7518652