Dr. Shen is the Director of Global Strategic Initiatives at Stanford Biodesign and founding U.S. Executive Director of the Singapore Stanford Biodesign Program. Chris is an Adjunct Professor of Medicine at Stanford University, responsible for Biodesign Asia Programs and Biodesign Affiliates, focused on training and mentoring faculty and students in medical technology innovation.
Dr. Shen is also a Managing Director at CBC Group, one of the largest Asia-based, healthcare-dedicated investment firms. With headquarters in Singapore, CBC is committed to building innovative companies that improve the health and quality of human life. Chris has over 20 years of experience in medical device design and innovation, and is focused on investments in the biopharma and medtech sectors. Previously, Chris held senior investing positions at Qiming Venture Partners, Vertex Healthcare/Temasek, EW Health, and New Enterprise Associates. Chris started his medtech career as a Senior Design Engineer at Guidant Neurovascular, where he was the principal inventor on one of the original stentriever devices for ischemic stroke.
Chris received his Doctor of Medicine from the Stanford School of Medicine, his Master of Business Administration from Stanford Graduate School of Business, and a Master of Biomechanical Engineering from the Stanford School of Engineering. He received his Bachelor of Science in Biological Sciences from Stanford University.
Dr. Shen teaches the Global Biodesign course: Global Biodesign: Medical Technology in an International Context – a project-based course that exposes students to the challenges and opportunities of developing and implementing innovative medical technologies to help patients around the world. He has authored twelve patents and has several pending in the fields of interventional neuroradiology and interventional cardiology.
Academic Staff - Hourly - CSL, Surgery
MD, Stanford University, School of Medicine
MBA, Stanford University, Graduate School of Business
MS, Stanford University, Biomechanical Engineering
BS, Stanford University, Biological Science
Relationship between hypnosis and personality trait in participants with high or low hypnotic susceptibility
NEUROPSYCHIATRIC DISEASE AND TREATMENT
2017; 13: 1007-1012
The relationship between normal personality and hypnotic susceptibility is important for understanding mental processing and mental disorders, but it is less consistent in normal people or in patients with a psychiatric disorder. We have hypothesized that the correlation exists but varies in individuals with different levels of hypnotizability.We invited 72 individuals with high (HIGH group) and 47 individuals with low (LOW group) hypnotic susceptibilities to undertake tests of NEO-PI-R and the Stanford Hypnotic Susceptibility Scale, Form C (SHSSC).The HIGH group scored significantly higher than the LOW group did on openness to experience and its facet openness to feelings. In the LOW group, SHSSC total was positively predicted by openness to ideas; age regression was positively predicted by openness to experience and negatively predicted by extraversion; anosmia to ammonia was negatively predicted by agreeableness; and negative visual hallucination was positively predicted by openness to experience. In the HIGH group, hallucinated voice was positively predicted by openness to experience and negatively predicted by agreeableness, and posthypnotic amnesia was positively predicted by extraversion and negatively predicted by openness to experience.The associations between normal personality traits and hypnotic susceptibility items were weak and different in the two groups, which imply that managing mental or somatoform disorders might be through adjusting hypnotizability and mobilizing personality functions.
View details for DOI 10.2147/NDT.S134930
View details for Web of Science ID 000398557700001
View details for PubMedID 28435270
Outcomes from a Postgraduate Biomedical Technology Innovation Training Program: The First 12 Years of Stanford Biodesign
ANNALS OF BIOMEDICAL ENGINEERING
2013; 41 (9): 1803-1810
The Stanford Biodesign Program began in 2001 with a mission of helping to train leaders in biomedical technology innovation. A key feature of the program is a full-time postgraduate fellowship where multidisciplinary teams undergo a process of sourcing clinical needs, inventing solutions and planning for implementation of a business strategy. The program places a priority on needs identification, a formal process of selecting, researching and characterizing needs before beginning the process of inventing. Fellows and students from the program have gone on to careers that emphasize technology innovation across industry and academia. Biodesign trainees have started 26 companies within the program that have raised over $200 million and led to the creation of over 500 new jobs. More importantly, although most of these technologies are still at a very early stage, several projects have received regulatory approval and so far more than 150,000 patients have been treated by technologies invented by our trainees. This paper reviews the initial outcomes of the program and discusses lessons learned and future directions in terms of training priorities.
View details for DOI 10.1007/s10439-013-0761-2
View details for Web of Science ID 000323736800002
View details for PubMedID 23404074
Feasibility of external beam radiation for prevention of restenosis following balloon angioplasty
INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS
1999; 44 (2): 363-367
Brachytherapy has been shown to inhibit neointima formation after vascular balloon injury. This study was done to test the feasibility of low dose external radiation for prevention of restenosis in a non-stented balloon injury model.Twelve red Duroc swine underwent balloon overdilation injury of both iliac arteries. Twelve Gy was delivered to one side using a Theratron T-1000 Cobalt unit with the other side used as the control. Twelve weeks post injury arteriograms were performed. The animals were then sacrificed and iliac arteries explanted. Histomorphometric analysis of arterial cross sections was performed. Results: Neointima formation was observed in all arteries. Unilateral thrombosis was noted in two animals. The mean neointimal thickness in the radiated and control arteries was 0.63 +/- 0.17 mm and 0.72 +/- 0.31 mm, respectively. The differences in minimal luminal diameter and the neointimal thickness between the two groups were not statistically significant. Complications included superficial hair loss in the radiation port in 4 animals, and 2 deaths prior to the completion date (1 of hemorrhagic enteritis possibly related to the radiation, and 1 of iliac rupture).External radiation at this low dose is not effective in preventing vascular restenosis following balloon injury in this animal model.
View details for Web of Science ID 000079910400020
View details for PubMedID 10760432