Dany Lamothe, MD

All Publications

• From obstruction to avoidance: A case of transition from anorexia nervosa to ARFID after superior mesenteric artery syndrome Lamothe, D. PERGAMON-ELSEVIER SCIENCE LTD. 2026

  View details for DOI 10.1016/j.jpsychores.2026.112810

  View details for Web of Science ID 001800403000012

• Psychological Symptoms and Adverse Childhood Experiences Negatively Impact Coexisting Obstructed Defecation and Fecal Incontinence Symptoms. Neurogastroenterology and motility Karhu, E., Gurland, B., Craven, M. R., Lamothe, D., Neshatian, L. 2026; 38 (1): e70243

  Abstract

  Many patients with obstructed defecation report concurrent fecal incontinence. However, the impact of psychological factors on coexisting symptoms remains unclear. We aimed to investigate the association between history of adverse childhood experiences (ACEs) and psychological symptoms on the severity of coexisting obstructed defecation and fecal incontinence.Retrospective analysis of a prospective IRB registry of patients with primary complaint of obstructed evacuation symptoms who completed validated surveys for assessment of psychological symptoms using the Hospital Anxiety and Depression Scale (HADS), the Adverse Childhood Experiences (ACE) questionnaire, and clinical characteristics including symptom severity.A total of 128 patients with obstructed defecation and fecal incontinence (110 women), average (SD) age 55 (16) years, were included; mean Renzi Obstructed Defecation Syndrome (ODS) score of 9.75 (3.97) and mean Cleveland Clinic Fecal Incontinence (CCFI) score of 9.38 (5.54). ACEs were reported by 60 (47%) and HADS anxiety and depression ≥ 8 by 63 (49%) and 36 (28%) of the cohort, respectively. Patients with ACEs had more severe ODS (not CCFI) scores which correlated with higher HADS anxiety and depression scores. There were no correlations between CCFI and HADS anxiety and depression scores (p > 0.05). Younger patients were more likely to report ACEs, higher HADS, ODS and lower CCFI scores. After adjusting for age, higher depression scores correlated significantly with the severity of both CCFI and ODS scores.The observed differences in the impact of ACEs and psychological symptoms on coexisting obstructed defecation and fecal incontinence symptoms suggest distinct pathophysiological mechanisms, which could guide targeted treatment strategies across different age groups.

  View details for DOI 10.1111/nmo.70243

  View details for PubMedID 41578674

• Outpatient GI Behavioral Medicine: An Analysis of Psychiatric Referrals in Gastroenterology-Patient Characteristics, Diagnoses, and Preliminary Health Outcomes Lamothe, D. ELSEVIER SCIENCE INC. 2025

  View details for DOI 10.1016/j.jaclp.2025.10.260

  View details for Web of Science ID 001632287200016

• Rectal Prolapse Repair Improves Bowel Symptoms in Women With Psychiatric Disorders: A Cohort Analysis of a Single-Center Registry. Diseases of the colon and rectum Rajasingh, C. M., Earley, M., Akeel, N., Bungo, C., Au Hoy, S., Lamothe, D., Neshatian, L., Gurland, B. H. 2025

  Abstract

  Psychiatric disorders are prevalent in patients with rectal prolapse. While psychiatric disorders are associated with poor surgical outcomes and worse health in general, it is unknown how they impact rectal prolapse repair.To determine rectal prolapse symptom severity in patients with psychiatric disorders and how surgical repair modified these symptoms.Retrospective analysis of a prospectively maintained database.Academic colorectal practice.Female patients with and without psychiatric comorbidities who underwent rectal prolapse repair with preoperative and 1-year postoperative Pelvic Floor Distress Inventory (PFDI-20) scores.One-year change in PFDI-20 score.Of 365 female patients in our registry, 146 met inclusion criteria. 54 (36%) had a psychiatric disorder. Depression (66%) and anxiety (44%) were the most prevalent conditions. Patients with a psychiatric disorder were significantly younger (median [IQR] age: 61 [48, 67] vs. 70 [60,77], p<0.001) but otherwise had a similar prevalence of comorbidities such as cardiac disease. Preoperative symptom profile was similar, but patients with psychiatric disorders reported higher PFDI-20 scores reflecting greater prolapse-related distress (mean [SD]: 146 [70] vs 115 [55], p = 0.01). Postoperatively, PFDI-20 scores improved significantly in both groups (adjusted mean change from baseline for patients with rectal prolapse repair: psychiatric disorders: -88 [-130, -47] vs. no psychiatric disorders: -44 [-68, -19]). Models did not reveal statistically significant differential improvement between groups, though patients with psychiatric disorders tended to have greater improvement in their scores compared to patients without psychiatric disorders.Single-center study with limited data on psychiatric comorbidity severity and disease control.Rectal prolapse patients with psychiatric disorders suffer from prolapse-related distress at baseline but experience significant improvement after surgical repair, suggesting that appropriate management of rectal prolapse can improve their quality of life. Long-term durability of symptom improvement should be the focus of further work. See Video Abstract.

  View details for DOI 10.1097/DCR.0000000000003964

  View details for PubMedID 40970548

• The Policy Landscape for Armed Personnel in Health Care Facilities: A Preliminary Scoping Review of State Policies Priest, K., Lamothe, D. ELSEVIER SCIENCE INC. 2023: S80-S81

  View details for DOI 10.1016/j.jaclp.2023.11.633

  View details for Web of Science ID 001161339100153

• An Opened Space for The Elaboration of the Suffering of the Caregiver: ReFLections on the Training Course in Ethics at the University of Sherbrooke (French) Lamothe , D., Bergeron , B., Hassoun , J., Roy-Desruisseaux, . Can. J. Bioeth. 2020
• Conceptual and ethical problems in screening for major depressive disorder DEVELOPMENTS IN NEUROETHICS AND BIOETHICS, VOL 2: MENTAL HEALTH AS PUBLIC HEALTH: INTERDISCIPLINARY PERSPECTIVES ON THE ETHICS OF PREVENTION Lamothe, D., Gupta, M. edited by Cratsley, K., Radden, J. 2019: 145-165

  View details for DOI 10.1016/bs.dnb.2019.05.002

  View details for Web of Science ID 000631377700008

• The Support of the Subject in a World of Globalization: Narrative and Discussion Around a Clinical Case (French) Lamothe, D., Duchesne, A. Correspondances, The Magazine of the Freudian School of Québec, vol 20, no 1. 2019
• Psychiatry and Globalisation: a Resident's Perspective (French) ). Correspondances, The Magazine of the Freudian School of Québec, vol 19, no 1, December B.-Duchesne, A., Pham Thi Desmarteau, S., Lamothe, D. 2018
• Huge malignant solitary fibrous tumor of the pleura. General thoracic and cardiovascular surgery Arab, W. A., Lamoth, D., Echavé, V., Rizcallah, E., Sirois, M. 2012; 60 (6): 397-400

  Abstract

  Solitary fibrous pleural tumors are rare mesenchymal tumors that can be mistaken for mesothelioma. A positive staining of vimentin, negative staining of cytoplasmic keratin, and expression of the CD34 antigen can confirm their diagnosis. These tumors should be surgically excised although they are benign because they have malignant potential and tendency for recurrence.We present here a 63-year-old patient who had an inconclusive biopsy of a huge right intrathoracic lesion. Further testing after radical surgical resection revealed a malignant solitary fibrous pleural tumor. Surgery was complicated with injury of the thoracic duct. Patient was re-operated upon for ligation of the thoracic duct. He is doing well with no recurrence after 18 months of follow-up.In conclusion, definitive treatment for solitary fibrous tumor is radical surgical resection with close follow-up for the recurrences. Follow-up of this tumor is essential especially when it showed malignant features on pathological examination.

  View details for DOI 10.1007/s11748-012-0014-6

  View details for PubMedID 22566249