iPSC model of congenital heart disease predicts disease outcome.
Cell stem cell
2022; 29 (5): 659-660
In this issue of Cell Stem Cell, Xu etal. demonstrate that induced pluripotent stem cell-derived cardiomyocytes from patients with hypoplastic left heart syndrome exhibit mitochondrial dysfunction and can be used for disease modeling. In addition, they show the potential to predict future heart failure and develop therapies.
View details for DOI 10.1016/j.stem.2022.04.010
View details for PubMedID 35523134