Clinical Focus

  • Surgical Pathology
  • Anatomic and Clinical Pathology

Academic Appointments

  • Clinical Instructor, Pathology

Professional Education

  • Medical Education: Medical College of Georgia at Augusta University (2018) GA
  • Fellowship: Stanford University Pathology Fellowships (2024) CA
  • Fellowship: Stanford University Pathology Fellowships (2023) CA
  • Board Certification: American Board of Pathology, Anatomic and Clinical Pathology (2022)
  • Residency: University of Alabama at Birmingham Pathology Residency (2022) AL
  • MD, Medical College of Georgia (2018)
  • Pathology Residency, University of Alabama at Birmingham (2022)
  • Surgical Pathology Fellowship, Stanford (2023)
  • GI Pathology Fellowship, Stanford (2024)

Contact

  • Clinical (Primary)  Pathology 300 Pasteur Dr Rm L235 MC 5324 Palo Alto, CA 94304 (650) 725-6902 (fax)

Additional Clinical Info

Additional Info

  • Mail Code: 5324

All Publications

  • Hepatic adenomas in males: Is molecular characterization helpful in guiding its management? HUMAN PATHOLOGY Jain, E., Anderson, S. A., Ollila, E., Johnson, D., Chandrashekar, D., Osme, A., Goksel, B., Lee, G., Al Diffalha, S., Kakar, S., Harada, S., Dhall, D. 2025; 159: 105795

    Abstract

    Hepatocellular adenomas (HCAs) in males are very rare. We performed detailed clinicopathologic, immunohistochemical and molecular characterization of HCAs in males, to understand their pathogenesis and malignant potential.Seven cases of HCA in males formed our study cohort. The histologic slides, clinical and follow-up information were reviewed and immunohistochemical stains were performed. DNA was extracted and targeted sequencing was performed using Ion Torrent chemistry. Filtered variants were annotated to identify pathogenic mutations.Six (86 %) patients were morbidly obese. All showed at least focal cytologic atypia. Three lesions were markedly steatotic and 2 were hemorrhagic. One lesion showed focal reticulin loss, diffuse glutamine synthetase (GS) positivity and beta-catenin (β-catenin) nuclear staining, suggestive of atypical hepatocellular neoplasm. Three (42.8 %) cases were inflammatory-type, showing diffuse serum amyloid-associated protein/C-reactive protein. One other inflammatory-type HCA showed peripheral accentuation with GS and another non-inflammatory HCA showed patchy staining with GS; both revealed CTNBB1 mutations but no β-catenin nuclear staining. None showed TP53, TERT promotor mutations, or significant copy number alterations.A significant proportion of HCAs in males occurred in obese patients and were inflammatory-type. While some are beta-catenin mutated and need to be resected, a subset of HCAs in males appears to be low-risk by molecular features and may be treated conservatively.

    View details for DOI 10.1016/j.humpath.2025.105795

    View details for Web of Science ID 001496947600001

    View details for PubMedID 40379140

  • Can Steatohepatitis Be Classified as Non-alcoholic or Alcoholic Based on Histologic Features Alone? Ollila, E., Fakhari, M., Charu, V., Tan, S., Kambham, N., Higgins, J. ELSEVIER SCIENCE INC. 2024: S1692

    View details for Web of Science ID 001302363406046