Clinical Focus


  • Neurology

Academic Appointments


Professional Education


  • Fellowship: Stanford University Dept of Neurology (2022) CA
  • Board Certification: American Board of Psychiatry and Neurology, Neurology (2021)
  • Residency: Stanford University Dept of Neurology (2021) CA
  • Internship: Cedars Sinai Medical Center Internal Medicine Residency (2018) CA
  • Medical Education: University of Pennsylvania Hospital (2017) PA

All Publications


  • Cryptogenic new-onset refractory status epilepticus (NORSE) following blood transfusion in a patient with severe anemia. Epileptic disorders : international epilepsy journal with videotape Wu, C. K., Culbertson, C. J., Von Stein, E. L., Walia, S., Krishnamohan, P., Threlkeld, Z. D. 2021

    Abstract

    New-onset refractory status epilepticus (NORSE) is a rare neurological emergency in which a patient without prior seizure disorder develops seemingly unprovoked status epilepticus refractory to treatment. We report the case of a middle-aged woman who developed NORSE after receiving multiple blood transfusions for subacute blood loss anemia secondary to menorrhagia. Although the mechanism is unclear, we propose that sudden changes in blood viscosity and vasogenic tone resulted in cortical edema and irritation. Although seizures have been documented in patients who undergo blood transfusion and develop posterior reversible encephalopathy syndrome (PRES), there was no radiographic evidence of PRES in this case. This is the first reported case of cryptogenic NORSE following blood transfusion.

    View details for DOI 10.1684/epd.2021.1267

    View details for PubMedID 33881399

  • Cryptogenic new-onset refractory status epilepticus (NORSE) following blood transfusion in a patient with severe anemia Wu, C., Von Stein, E., Culbertson, C., Walia, S., Krishnamohan, P., Threlkeld, Z. LIPPINCOTT WILLIAMS & WILKINS. 2020