Bio


Dr. Edelstein’s research and practice focus on the measurable impact of the built environment on human performance, health, wellbeing. Eve’s ongoing collaboration with a national quality improvement study explores the impact of noise in operating rooms with Stanford, Harvard, Vanderbilt, Pennsylvania, and other members of SPA.

Eve's recent work with Google and the International WELL Building Institute, explores how the built environment can support the unique abilities of providers and the people they serve to enhance performance and outcomes.

Dr. Edelstein's clinical service and doctoral research at University College London and the National Hospital for Neurology & Neurosurgery, and at the Harvard MIT hearing sciences lab developed and used electrophysiological techniques to show the brain’s efferent control of cochlear function. Eve's degrees in in Anthropology (University California Berkeley), and Master of Architecture offer a unique background for her contributions as a Board member of the Academy of Neuroscience for Architecture, the AIA College of Fellows Latrobe Prize on circadian design, the Berkeley Teaching Prize on Neuro-Universal Design, and the Calit2 Strategic Opportunities Award for Virtual Visual and Acoustic hospital design for the University of California San Diego.

Dr. Edelstein co-founded Clinicians for Design and Neuro-Architecture, and contributed to award-winning hospital designs, including master planning through architectural and interior solutions for top-tier academic and medical centers, educational facilities, and building projects in the US, Canada, UK, and China.

Academic Appointments


  • Casual - Other Teaching Staff, Continuing Studies and Summer Session

All Publications


  • A loud call for silence: anaesthesiologists' perceptions of noise in the operating room BRITISH JOURNAL OF ANAESTHESIA Crockett, C. J., Dalal, P. G., Tjia, I., Allen, M., Edelstein, E., Feng, X., French, B., Brustowicz, R. M. 2024; 132 (2): 444-447

    View details for DOI 10.1016/j.bja.2023.11.035

    View details for Web of Science ID 001168612300001

    View details for PubMedID 38101964

  • NEURO-DESIGN: HOW THE FORM AND FUNCTION OF THE BRAIN REVEALS DESIGN'S DELIGHT JOURNAL OF INTERIOR DESIGN Edelstein, E. A. 2022; 47 (1): 7-9

    View details for DOI 10.1111/joid.12216

    View details for Web of Science ID 000770054600003

  • ENGAGING THE MIND: NEUROSCIENCE IN THE DESIGN PROCESS INTRODUCTION JOURNAL OF INTERIOR DESIGN Otis, J., Edelstein, E. A. 2022; 47 (1): 3-6

    View details for DOI 10.1111/joid.12215

    View details for Web of Science ID 000770054600002

  • Neuroscience and Architecture ROUTLEDGE COMPANION FOR ARCHITECTURE DESIGN AND PRACTICE: ESTABLISHED AND EMERGING TRENDS Edelstein, E. edited by Kanaani, M., Kopec, D. 2016: 269-287
  • CaveCAD: Architectural Design in the CAVE Hughes, C. E., Zhang, L., Schulze, J. P., Edelstein, E., Macagno, E. edited by Lecuyer, A., Steinicke, F., Billinghurst, M. IEEE COMPUTER SOC. 2013: 193-194
  • Form Follows Function: Bridging Neuroscience and Architecture SUSTAINABLE ENVIRONMENTAL DESIGN IN ARCHITECTURE: IMPACTS ON HEALTH Edelstein, E. A., Macagno, E. edited by Rassia, S. T., Pardalos, P. M. 2012; 56: 27-41
  • Wireless Physiological Monitoring and Ocular Tracking: 3D Calibration in a Fully-Immersive Virtual Health Care Environment Zhang, L., Chi, Y., Edelstein, E., Schulze, J., Gramann, K., Velasquez, A., Cauwenberghs, G., Macagno, E., IEEE IEEE. 2010: 4464-4467

    Abstract

    Wireless physiological/neurological monitoring in virtual reality (VR) offers a unique opportunity for unobtrusively quantifying human responses to precisely controlled and readily modulated VR representations of health care environments. Here we present such a wireless, light-weight head-mounted system for measuring electrooculogram (EOG) and electroencephalogram (EEG) activity in human subjects interacting with and navigating in the Calit2 StarCAVE, a five-sided immersive 3-D visualization VR environment. The system can be easily expanded to include other measurements, such as cardiac activity and galvanic skin responses. We demonstrate the capacity of the system to track focus of gaze in 3-D and report a novel calibration procedure for estimating eye movements from responses to the presentation of a set of dynamic visual cues in the StarCAVE. We discuss cyber and clinical applications that include a 3-D cursor for visual navigation in VR interactive environments, and the monitoring of neurological and ocular dysfunction in vision/attention disorders.

    View details for DOI 10.1109/IEMBS.2010.5625969

    View details for Web of Science ID 000287964004215

    View details for PubMedID 21095772

  • Building Health HERD-HEALTH ENVIRONMENTS RESEARCH & DESIGN JOURNAL Edelstein, E. A. 2008; 1 (2): 54-59

    Abstract

    Biological and medical research offer rigorous techniques and scientific methodologies to explore how features of the built environment influence human health, performance, and well-being. Practice guidelines from evidence-based medicine and translational science provide models for translating biomedical information into design principles applicable to healthcare environments. Examples from recent scientific discoveries highlight how scientific evidence may inform healthcare design. The interaction between stress and environmental stimuli such as light, sound, and location are relevant to patients, visitors, and staff, influencing cardiac and stress responses as well as cognitive functions such as memory and navigation abilities. Research demonstrating the pervasive influence of light on human biological systems includes epidemiological and laboratory studies that suggest an association between light exposure and increased cardiac or cancer risk. Advances in laboratory research and the development of wearable devices that may be used on-site in healthcare settings facilitate more precise measurement of the environmental features that influence healthcare users and providers. The data derived may serve as the foundation for new evidence-based performance criteria, supporting the use of existing materials and methods, as well as the creation of new design solutions to meet health needs in addition to operational outcomes.

    View details for DOI 10.1177/193758670800100208

    View details for Web of Science ID 000273357100008

    View details for PubMedID 21161898

  • EFFECTS OF OLIVOCOCHLEAR BUNDLE SECTION ON OTOACOUSTIC EMISSIONS IN HUMANS - EFFERENT EFFECTS IN COMPARISON WITH CONTROL SUBJECTS ACTA OTO-LARYNGOLOGICA WILLIAMS, E. A., BROOKES, G. B., PRASHER, D. K. 1994; 114 (2): 121-129

    Abstract

    The effects of contralateral acoustic stimulation on evoked otoacoustic emissions (OAE) were examined in three subject groups in order that the impact of efferent olivocochlear bundle section (as a consequence of vestibular neurectomy) could be compared with normal findings, and with a control surgical population. Results demonstrated that the inhibitory effect of contralateral noise on OAE amplitude was absent from the cochlea with severed efferent fibers. These findings appear to be independent of acoustic reflex activity, as suppression was absent despite normal reflexes. Inter-aural suppression of emissions recorded from the patients' intact cochleae act as a control and show a clear reduction in amplitude during contralateral stimulation in a frequency specific pattern consistent with normal findings. Patients who had undergone a similar surgical approach for vascular decompression of the VIIIth nerve without vestibular nerve section, were studied in order to assess the impact of retrolabyrinthine surgery on inter-aural suppression. Inhibition of OAE amplitude was maintained in all control cases in both the operated and intact sides, and was consistent with suppression observed in normal subjects, suggesting that the surgical procedures had not disturbed inter-aural suppression of otoacoustic emissions. It is concluded that the olivocochlear efferent system, when activated by low level contralateral acoustic stimulation, has an inhibitory role in controlling the cellular mechanisms responsible for the generation of otoacoustic emissions in humans. OAE techniques in conjunction with contralateral acoustic stimulation may thus prove to be of value in providing a rapid and non-invasive clinical test of efferent function and offer a means of investigating the functional significance of the efferent auditory system in humans.

    View details for DOI 10.3109/00016489409126029

    View details for Web of Science ID A1994ND13500002

    View details for PubMedID 8203191

  • EFFECTS OF CONTRALATERAL ACOUSTIC STIMULATION ON OTOACOUSTIC EMISSIONS FOLLOWING VESTIBULAR NEURECTOMY SCANDINAVIAN AUDIOLOGY WILLIAMS, E. A., BROOKES, G. B., PRASHER, D. K. 1993; 22 (3): 197-203

    Abstract

    This study demonstrates that, following unilateral vestibular neurectomy, the inhibitory effect of contralateral acoustic stimulation on evoked otoacoustic emissions is absent. The patient acts as her own control in that the unoperated side shows normal suppression of otoacoustic emission amplitude with contralateral acoustic stimulation. The lack of interaural suppression of otoacoustic emissions on the sectioned side, in the presence of normal acoustic reflex threshold levels, provides evidence that observed phenomena are not merely a function of middle ear reflex activity. It is concluded that the lack of inhibition in the operated ear is due to the sectioning of the olivocochlear bundle within the inferior vestibular nerve, removing the efferent control of the receptor cells. Otoacoustic emissions recorded during contralateral acoustic stimulation may thus provide a rapid, non-invasive means of investigating the functional of the efferent auditory system.

    View details for DOI 10.3109/01050399309047469

    View details for Web of Science ID A1993LT52800009

    View details for PubMedID 8210961