Bio


Dr. Earth Hasassri is a Clinical Fellow of Child & Adolescent Psychiatry within the Department of Psychiatry and Behavioral Sciences at Stanford University School of Medicine and Lucile Packard Children's Hospital at Stanford. He specializes in seeing patients for complex psychiatric conditions such as psychotic experiences and autism spectrum disorders. His interests are caring for individuals who suffer from medical conditions at the interface of medicine and psychiatry. In addition, he treats children with a broad range of psychiatric disorders including neurodevelopmental disorders, ADHD and mood and anxiety disorders in adolescents.

Prior to medical school, Dr. Hasassri graduated with dual bachelor's degrees in neurophysiology and psychology at the University of California San Diego, where he performed research on sleep medicine. He earned his medical degree from the Mayo Clinic Alix School of Medicine where he did research in clinical epidemiology. Dr. Hasassri completed his residency in general psychiatry at the University of California San Francisco Langley Porter Psychiatric Hospitals & Clinics, during which he was awarded an Area of Distinction in Clinical Neuroscience for his work in applying neuroscientific principles in his clinical work in those with brain cancer, dementia, neurodevelopmental disorders, and other neuropsychiatric conditions. Dr. Hasassri is a board certified general psychiatrist and is currently pursuing further training through a fellowship here at Stanford to obtain subspecialty board certification in child and adolescent psychiatry.

Dr. Hasassri's scientific interest focus on bringing novel interventional treatments to children and adolescents, such as transcranial magnetic stimulation. He is currently working with Dr. Nolan Williams and Dr. Antonio Hardan in their laboratories studying whether transcranial magnetic stimulation is safe and effective for children and adolescents, particularly in those with autism spectrum disorders.

Clinical Focus


  • Fellow
  • Psychiatry
  • Child and Adolescent Psychiatry
  • Neuropsychiatry
  • Interventional Psychiatry

Professional Education


  • Fellowship, Stanford University/Lucile Packard Children's Hospital, Child & Adolescent Psychiatry (2022)
  • Residency, University of California, San Francisco (UCSF), General Psychiatry (2020)
  • M.D., Mayo Clinic Alix School of Medicine, Medicine (2017)
  • B.A., University of California, San Diego (UCSD), Psychology (2012)
  • B.S., University of California, San Diego (UCSD), Physiology & Neuroscience (2012)

All Publications


  • Characterization of Admission Types in Medically Hospitalized Patients Prescribed Clozapine. Psychosomatics Leung, J. G., Hasassri, M. E., Barreto, J. N., Nelson, S. n., Morgan, R. J. 2016; 58 (2): 164–72

    Abstract

    Clozapine is the antipsychotic of choice for treatment-resistant schizophrenia; however, rigorous monitoring is required to prevent or detect adverse drug events that contribute to morbidity and mortality. In addition to the Food and Drug Administration (FDA) boxed safety warnings specific to clozapine (agranulocytosis, hypotension, seizures, and cardiomyopathy/myocarditis), other adverse events such as pneumonia and gastrointestinal hypomotility have been reported in the literature to result in hospitalization.To explore the reasons for medical hospitalization in patients prescribed clozapine, a retrospective chart review was completed.Adults with schizophrenia or schizoaffective disorder prescribed clozapine were identified if they had a nonpsychiatric medical admission between 1/1/2003 and 8/1/2015. Demographics, admitting diagnosis, admitting service type, psychiatric consult information, clozapine dosing, and drug interactions were collected.Overall, 104 patients, representing 248 hospitalizations, were admitted to a medical unit during the study period. The predominant admission types were for the management of either pulmonary (32.2%) or gastrointestinal (19.8%) illnesses. The most common pulmonary diagnosis was pneumonia, accounting for 58% of pulmonary admissions. Further, 61.2% of the gastrointestinal admissions were related to hypomotility, ranging from constipation to death. Clozapine was discontinued owing to neutropenia in 2 patients; however, in both cases concomitant chemotherapy had been given.In patients prescribed clozapine admitted to nonpsychiatric medical settings, gastrointestinal and pulmonary illnesses were common, but not illnesses related to boxed warnings. Additional research is needed to better assess the causality and true incidence of gastrointestinal or pulmonary events associated with clozapine. Furthermore, clinicians must be prepared to prevent, detect, and manage potentially life-threatening events associated with clozapine.

    View details for DOI 10.1016/j.psym.2016.11.013

    View details for PubMedID 28153339

  • Unvaccinated and Stuporous: Catatonia as a Feature of Subacute Sclerosing Panencephalitis Northern California Psychiatric Society Annual Meeting Hasassri, M., Datta, V. 2019
  • Cannabinoid Hyperemesis Syndrome masquerading as a Schizophrenia Spectrum Disorder IPS: The Mental Health Services Conference Hasassri, M. E., Wood, K. 2019
  • Heterogeneity of asthma and the risk of celiac disease in children. Allergy and asthma proceedings Patel, B. n., Wi, C. I., Hasassri, M. E., Divekar, R. n., Absah, I. n., Almallouhi, E. n., Ryu, E. n., King, K. n., Juhn, Y. J. 2018; 39 (1): 51–58

    Abstract

    Although human leukocyte antigen (HLA)-DR and HLA-DQ genes and gluten play crucial roles in developing celiac disease (CD), most patients with these risk factors still do not develop CD, which indicates additional unrecognized risk factors.To determine the association between asthma and the risk of CD in children.We conducted a population-based retrospective case-control study in children who resided in Olmsted County, Minnesota. We identified children with CD (cases) between January 1, 1997, and December 31, 2014, and compared these with children without CD (controls) (1:2 matching). Asthma status was ascertained by using the predetermined asthma criteria (PAC) and the asthma predictive index (API). Data analysis included conditional logistic regression models and an unsupervised network analysis by using an independent phenome-wide association scan (PheWAS) data set.Although asthma status as determined by using PAC was not associated with the risk of CD (odds ratio [OR] 1.4 [95% confidence interval {CI}, 0.8-2.5]; p = 0.2), asthma status by using the API was significantly associated (OR 2.8 [95% CI, 1.3-6.0]; p = 0.008). A subgroup analysis indicated that children with both asthma as determined by using PAC and a family history of asthma had an increased risk of CD compared with those without asthma (OR 2.28 [95% CI, 1.11-4.67]; p = 0.024). PheWAS data showed a cluster of asthma single nucleotide polymorphisms and patients with CD.A subgroup of children with asthma who also had a family history of asthma seemed to be at an increased risk of CD, and, thus, the third factor that underlies the risk of CD might be related to genetic factors for asthma. Heterogeneity of asthma plays a role in determining the risk of asthma-related comorbidity.

    View details for DOI 10.2500/aap.2018.39.4100

    View details for PubMedID 29279060

    View details for PubMedCentralID PMC5743845

  • Asthma and Risk of Appendicitis in Children: A Population-Based Case-Control Study. Academic pediatrics Hasassri, M. E., Jackson, E. R., Ghawi, H. n., Ryoo, E. n., Wi, C. I., Bartlett, M. G., Volcheck, G. W., Moir, C. R., Ryu, E. n., Juhn, Y. J. 2017; 17 (2): 205–11

    Abstract

    To assess whether asthma is associated with risk of appendicitis in children.We used a population-based case-control study design using a comprehensive medical record review and predetermined criteria for appendicitis and asthma. All children (age younger than 18 years of age) who resided in Olmsted County, Minnesota, and developed appendicitis between 2006 and 2012 were matched to controls (1:1) with regard to birthday, gender, registration date, and index date. Asthma status was ascertained using predetermined criteria. Active (current) asthma was defined as the presence of asthma symptoms or asthma-related events (eg, medication use, clinic visits, emergency department, or hospitalization) within 1 year before the index date. Inactive asthma was defined as subjects without these events. A conditional logistic regression model was used.Among the 309 appendicitis cases identified, when stratified according to asthma status, active asthma was associated with significantly increased risk of appendicitis compared with inactive asthma (odds ratio [OR] = 2.48; 95% confidence interval [CI], 1.22-5.03) and to no asthma (OR = 1.88; 95% CI, 1.07-3.27; overall P = .035). When controlling for potential confounders such as gender, age, and smoking status, active asthma was associated with a higher odds of developing appendicitis compared with nonasthmatic patients (adjusted OR = 1.75; 95% CI, 0.99-3.11) whereas inactive asthma was not (overall P = .049). Tobacco smoke exposure within 3 months was associated with an increased risk of appendicitis (adjusted OR = 1.66; 95% CI, 1.02-2.69). Among asthma medications, leukotriene receptor antagonists reduced the risk of appendicitis (OR = 0.18; 95% CI, 0.04-0.74).Active asthma might be an unrecognized risk factor for appendicitis in children whereas a history of inactive asthma does not pose such risk. Further investigation exploring the underlying mechanisms is warranted.

    View details for DOI 10.1016/j.acap.2016.09.006

    View details for PubMedID 27964827

    View details for PubMedCentralID PMC5337436

  • Pheochromocytoma with Synchronous Ipsilateral Adrenal Cortical Adenoma. World journal of surgery Hasassri, M. E., Pandian, T. K., Bobr, A. A., Bancos, I. n., Young, W. F., Richards, M. L., Farley, D. R., Thompson, G. B., McKenzie, T. J. 2017; 41 (12): 3147–53

    Abstract

    Pheochromocytoma with synchronous ipsilateral adrenal cortical adenoma (PSCA) may present with mixed clinical, biochemical, and radiological features characteristic to each neoplasm subtype.All patients with a pathological diagnosis of pheochromocytoma were evaluated for an ipsilateral cortical adenoma from 1994 through 2015. Retrospectively extracted data included indications for adrenalectomy, diagnostic workup (biochemical and radiographic), operative characteristics, pathological findings, and postoperative complications.Sixteen of 413 patients (4%) undergoing adrenalectomy for pheochromocytoma had a PSCA. Median patient age was 57.7 years (IQR 50.1, 63.1); 50% were male. On imaging, 75% of the adrenal neoplasms were found incidentally and only 50% were reported to have a synchronous ipsilateral neoplasm based on imaging findings. Clinically important cortical hormone secretion was diagnosed in 38% of these patients; 25% had glucocorticoid secretory autonomy; and 13% had primary aldosteronism.Physicians should be aware that adrenal neoplasms with mixed diagnostic findings may represent PSCA. Evaluation should be performed on this co-occurrence to prevent perioperative complications from resection of an unexpected secretory cortical neoplasm.

    View details for DOI 10.1007/s00268-017-4110-8

    View details for PubMedID 28762170

  • An Immunocompromised Child with Bloodstream Infection Caused by Two Escherichia coli Strains, One Harboring NDM-5 and the Other Harboring OXA-48-Like Carbapenemase (vol 60, pg 3270, 2016) ANTIMICROBIAL AGENTS AND CHEMOTHERAPY Hasassri, M., Boyce, T. G., Norgan, A. P., Cunningham, S. A., Jeraldo, P. R., Weissman, S. J., Patel, R., Banerjee, R., Pogue, J. M., Kaye, K. S. 2016; 60 (8): 5108

    View details for DOI 10.1128/AAC.01338-16

    View details for Web of Science ID 000380792600096

    View details for PubMedID 27451441

    View details for PubMedCentralID PMC4958178

  • An Immunocompromised Child with Bloodstream Infection Caused by Two Escherichia coli Strains, One Harboring NDM-5 and the Other Harboring OXA-48-Like Carbapenemase. Antimicrobial agents and chemotherapy Hasassri, M. E., Boyce, T. G., Norgan, A. P., Cunningham, S. A., Jeraldo, P. R., Weissman, S. J., Patel, R. n., Banerjee, R. n., Pogue, J. M., Kaye, K. S. 2016; 60 (6): 3270–75

    Abstract

    We describe a 16-year-old neutropenic patient from the Middle East with bloodstream infection caused by two carbapenemase-producing Escherichia coli isolates that we characterized by whole-genome sequencing. While one displayed meropenem resistance and was blaNDM positive, the other demonstrated meropenem susceptibility yet harbored blaOXA181 (which encodes a blaOXA48-like enzyme). This report highlights the challenge of laboratory detection of blaOXA48-like enzymes and the clinical implications of genotypic resistance detection in carbapenemase-producing Enterobacteriaceae.

    View details for DOI 10.1128/AAC.03118-15

    View details for PubMedID 27217442

    View details for PubMedCentralID PMC4879384

  • Attitudes and Perceived Needs on Pediatric Psychiatric Care in Developing Countries Klingenstein Child Psychiatry Conference Hasassri, M. E., Nguyen, K. D., Chan, L. 2016
  • Prevalence of Depression and Access to Mental Health Services in a Safety-Net, Free Clinic Population Mayo Clinic Family Medicine Forum Hasassri, M. E., Zayas, J., Murphy, S., Reiland, M., Moman, R., Cantwell, S., Emerling, E., Wieland, M. 2015