Clinical Focus

  • Hospice and Palliative Medicine

Academic Appointments

Professional Education

  • Board Certification: American Board of Internal Medicine, Hospice and Palliative Medicine (2025)
  • Fellowship: Stanford University Hospice and Palliative Care Fellowship (2025) CA
  • Board Certification: American Board of Internal Medicine, Internal Medicine (2024)
  • Residency: LACplusUSC Medical Center Internal Medicine Residency (2024) CA
  • Medical Education: University of Southern California Keck School of Medicine (2021) CA

Contact

  • Academic
    Department: Med/Primary Care and Population Health Position: Clinical Assistant Professor
  • Clinical (Primary)  Stanford Palliative Medicine 300 Pasteur Dr Rm HC005 MC 5277 Stanford, CA 94305 (650) 723-7056 (fax)

Additional Clinical Info

All Publications

  • Curli: Functional bacterial amyloid fibers Reichhardt, C., Rice, D., Uang, J., Cegelski, L. AMER CHEMICAL SOC. 2015

    View details for Web of Science ID 000411186503625

  • Congo Red Interactions with Curli-Producing E. coli and Native Curli Amyloid Fibers. PloS one Reichhardt, C., Jacobson, A. N., Maher, M. C., Uang, J., McCrate, O. A., Eckart, M., Cegelski, L. 2015; 10 (10): e0140388

    Abstract

    Microorganisms produce functional amyloids that can be examined and manipulated in vivo and in vitro. Escherichia coli assemble extracellular adhesive amyloid fibers termed curli that mediate adhesion and promote biofilm formation. We have characterized the dye binding properties of the hallmark amyloid dye, Congo red, with curliated E. coli and with isolated curli fibers. Congo red binds to curliated whole cells, does not inhibit growth, and can be used to comparatively quantify whole-cell curliation. Using Surface Plasmon Resonance, we measured the binding and dissociation kinetics of Congo red to curli. Furthermore, we determined that the binding of Congo red to curli is pH-dependent and that histidine residues in the CsgA protein do not influence Congo red binding. Our results on E. coli strain MC4100, the most commonly employed strain for studies of E. coli amyloid biogenesis, provide a starting point from which to compare the influence of Congo red binding in other E. coli strains and amyloid-producing organisms.

    View details for DOI 10.1371/journal.pone.0140388

    View details for PubMedID 26485271

    View details for PubMedCentralID PMC4618944