Laura T Derry

All Publications

• Defining Reference Values for Skeletal Muscle Metrics on Abdominal CT Using Data From Healthy Young Adult Populations: A Systematic Review and Meta-Analysis. AJR. American journal of roentgenology Ju, C., Yao, L., Yoon, S. Y., Lenchik, L., Johnston, A., Derry, L. T., Hom, J., Svec, D., Chaudhari, A. S., Boutin, R. D. 2025

  Abstract

  BACKGROUND. CT muscle metrics hold promise for opportunistic sarcopenia screening and individualized clinical risk stratification, but reference values applicable across broad populations are lacking. OBJECTIVE. To estimate reference cutoff values for CT skeletal muscle metrics using data from populations of healthy young adults. EVIDENCE ACQUISITION. The PubMed, Embase, Cochrane Library, Web of Science, and Scopus databases were searched through January 1, 2025 for studies reporting skeletal muscle index (SMI) and/or skeletal muscle density (SMD) on CT at the L3 vertebral level in healthy young adults (age range, 18-45 years). For SMI and SMD in both men and women, a random effects meta-analysis was used to estimate interstudy SD (as a measure of variance among studies) and mean values for a theoretic global population of healthy young adults. Presence of significant heterogeneity among individual study means was assessed using the Q statistic. Cutoff values for the theoretic global population corresponding with a T-score of -2 (i.e., values ≥ 2 SDs below the population's mean value) were calculated, incorporating the meta-analysis results and pooled intrastudy variance. EVIDENCE SYNTHESIS. The meta-analysis included 14 studies (16,958 individuals; 11,819 men, 5139 women) reporting SMI, of which seven studies (11,175 individuals; 8372 men, 2803 women) also reported SMD. The estimated global mean value for SMI was 54.6 in men and 42.4 in women and for SMD was 47.4 HU in men and 43.6 HU in women. The interstudy SD for SMI was 5.4 in men and 4.3 in women and for SMD was 1.9 in men versus 3.2 in women; significant heterogeneity was present among individual study means for both SMI and SMD in both men and women (all p<.001). The cutoff value corresponding with a T-score of -2 for SMI was 36.3 in men and 27.5 in women and for SMD was 36.4 HU in men and 28.1 HU in women. CONCLUSION. This meta-analysis of studies performed in healthy young adults provides reference mean values and standardized cutoffs analogous to a T-score of -2 for SMI and SMD at the L3 level on abdominal CT. CLINICAL IMPACT. These results can aid opportunistic screening for sarcopenia.

  View details for DOI 10.2214/AJR.25.32781

  View details for PubMedID 40334088

• Abstract 4115684: Outcomes Associated with Remote Monitoring without In-person Evaluations for Patients with Cardiovascular Implantable Electronic Devices Derry, L. T., Whooley, M., Raitt, M., Rotering, T., Shen, H., Tarasovsky, G., Dhruva, S. 2024

  View details for DOI 10.1161/circ.150.suppl_1.4115684

• Detecting Underdiagnosed Medical Conditions with Deep Learning-Based Opportunistic CT Imaging arXIV Aali, A., Johnston, A., Blankemeier, L., Van Veen, D., Derry, L., Svec, D., Hom, J., Boutin, R., Akshay, C. 2024
• Commotio Cordis in 2023 SPORTS MEDICINE Peng, T., Derry, L., Yogeswaran, V., Goldschlager, N. F. 2023; 53 (8): 1527-1536

  Abstract

  Since the nationally televised cardiac arrest of American National Football League player Damar Hamlin in January 2023, commotio cordis has come to the forefront of public attention. Commotio cordis is defined as sudden cardiac arrest due to direct trauma to the precordium resulting in ventricular fibrillation or ventricular tachycardia. While the precise incidence of commotio cordis is not known due to a lack of standardized, mandated reporting, it is the third most common cause of sudden cardiac death in young athletes, with more than 75% of cases occurring during organized and recreational sporting events. Given that survival is closely tied to how quickly victims receive cardiopulmonary resuscitation and defibrillation, it is crucial to raise awareness of commotio cordis so that athletic trainers, coaches, team physicians, and emergency medical personnel can rapidly diagnose and treat this often-fatal condition. Broader distribution of automated external defibrillators in sporting facilities as well as increased presence of medical personnel during sporting events would also likely lead to higher survival rates.

  View details for DOI 10.1007/s40279-023-01873-6

  View details for Web of Science ID 001020188900002

  View details for PubMedID 37382827

  View details for PubMedCentralID PMC10356869

• Peak Performance: A Communications-Based Leadership and Teamwork Simulation for Fourth-Year Medical Students JOURNAL OF MEDICAL EDUCATION AND CURRICULAR DEVELOPMENT Smithson, S., Beck Dallaghan, G., Crowner, J., Derry, L., Vijayakumar, A., Storrie, M., Daaleman, T. P. 2020; 7: 2382120520929990

  Abstract

  Medical education has traditionally been rooted in the teaching of health and disease processes, with little attention to the development of teamwork and leadership competencies.In an era of value-based health care provided by high-functioning teams, new approaches are needed to develop communication, leadership, and teamwork skills for medical students.We designed and piloted a simulation-based educational activity called Peak Performance that linked a workbook, which focused on self-reflection on communication and leadership skills, with professional coaching. The simulation scenario placed students in the role of an upper-level resident on an inpatient service, followed by a small group debrief with students, a clinical faculty member, and a professional executive coach. After the debriefing session, students were invited to complete a self-reflection workbook within 1 week of the initial simulation. The final element of the curriculum was an individualized session with an executive coach. Peak Performance was offered to all fourth-year medical students enrolled in the Social and Health Systems Science required course at the University of North Carolina School of Medicine.Pre-/post-self-assessments of leadership competencies were completed by students. Pre-simulation self-assessment scores ranged from 3.72 to 4.33 on a 5-point scale. The lowest scores were in "Managing Conflict" and "Managing Others." The highest score was in "Self-Awareness." The post-simulation scores decreased in every competency, with "Managing Others" dropping significantly from 3.72 pre-simulation to 3.36 post-simulation (0.31, P < .05). Satisfaction with the curriculum was high, as reflected by a Net Promoter Score of 91% ("excellent" > 50%).A novel simulation-based educational activity linked to professional coaching is a feasible and impactful strategy to develop leadership, communication, and teamwork skills in medical students. Student insight and self-awareness increased as evidenced by a decrease in competency self-assessment after guided reflection and individualized coaching.

  View details for DOI 10.1177/2382120520929990

  View details for Web of Science ID 000545601800001

  View details for PubMedID 32637637

  View details for PubMedCentralID PMC7318812

• A Student-Led National Conference on Leadership: Broadening the Medical Student Role. MedEdPublish (2016) Thomas, C., Mokshagundam, S., Pitkin, J., Andresen, R., Bunzel, E., Burk-Rafel, J., Cassell, A., Chiang, T., Derry, L., Merryman, E., Najibi, S., Pliakas, M., Saltzman, H., Steenbergh, K., Vijayakumar, A., Wagner, J., Yongue, C., Zink, K., Zurales, K., Tsai, T., Dekhtyar, M., Skochelak, S., Mangrulkar, R. 2019; 8: 133

  Abstract

  This article was migrated. The article was marked as recommended. Students have traditionally held a singular role in medical education - the learner. This narrow view neglects students unique perspective and ability to shape the future of medical education. In recognizing the need for deliberate leadership skill development and networking opportunities for medical student leaders, the American Medical Association (AMA) supported the first AMA Accelerating Change in Medical Education Student-Led Conference on Leadership in Medical Education. A planning committee of 19 students from seven medical schools collaborated to develop this conference, which took place on August 4-5, 2017 at the University of Michigan, Ann Arbor. The primary goal of the conference was for students to learn about leadership skills, connect with other student leaders, feel empowered to lead change, and continue to lead from their roles as students. Attendees participated in a variety of workshops and presentations focused on developing practical leadership skills. In addition, students formed multi-institutional teams to participate on in the MedEd Impact Challenge, attempting to address issues in medical education such as leadership curriculum development, wellness, and culture change. Post-conference surveys showed an overwhelming majority of students connected with other student leaders, shared ideas, developed collaborations, and felt empowered to enact change. Looking forward, we believe that similar student-led conferences focused on broadening the medical student role would provide avenues for positive change in medical education.

  View details for DOI 10.15694/mep.2019.000133.1

  View details for PubMedID 38089359

  View details for PubMedCentralID PMC10712505