Lauren Sue Grossman

All Publications

• Health Care Utilization in an Academic Integrative Medicine Center, 2011-2022 JOURNAL OF INTEGRATIVE AND COMPLEMENTARY MEDICINE Carroll, J. K., Gaona, G., Dong-Cedar, D., Williamson, T. J., Corbin, L. W., Nuffer, M., Pace, W. D., Palmer, C., Whalen, J., Shefferman, M., Nguyen, T., Valdez, C. M., Grossman, L., Tran, A. H., Greher, F. R., Hills, J., Palmer, F. 2025

  Abstract

  Objectives: As empirical evidence about the efficacy and therapeutic benefits of integrative medicine grows and insurance coverage of services increases, patient demand for integrative medicine is likely to increase. Relatively few studies have looked at electronic health records (EHRs) data to understand utilization of integrative medicine services within "real-world" practice settings. This study's objective is to describe sociodemographic data and health care utilization for adults (age 18 or older) within a large regional health system from 2011 to 2022. Methods: The study design was a longitudinal cohort analysis using EHRs data for patients seen at an integrative medicine center from 2011 to 2022. Setting/Location: UCHealth Integrative Medicine Center ("the Center") within UCHealth, a not-for-profit health care system with hospitals and clinical facilities throughout Colorado, southern Wyoming, and western Nebraska. Participants: Adults 18 years or older at the time of care delivery seen at the Center from April 1, 2011, through December 31, 2022. Results: The Center provided 95,754 visits to 15,157 unique individuals from April 1, 2011, through December 31, 2022. The average number of individuals seen was 1,833 per year (Range 1,405-2,347). The cohort's mean age was 43 years; the majority were female (75%) and white (77.2%) with commercial insurance (87.1%). Medicare (29.6%) and Medicaid (19.7%) insurance were also relatively common. The Social Deprivation Index scores were distributed broadly across the cohort. The top three reasons for visits were chronic pain, mental/behavioral health conditions, and obesity. The most frequent visits were for acupuncture, massage, and physician/physician assistant services. A total of 1,586 health care professionals from 52 different specialties, both within and outside UCHealth, referred to the Center. Conclusion: This study describes a large cohort of adults seen for integrative medicine services and referral sources within a large regional health care system. Study findings have the potential to shape future integrative health care provision, education, research, and policy.

  View details for DOI 10.1089/jicm.2023.0758

  View details for Web of Science ID 001437109200001

  View details for PubMedID 40040527

• Post-COVID-19 Vaccination and Long COVID: Insights from Patient-Reported Data. Vaccines Quach, T. C., Miglis, M. G., Tian, L., Bonilla, H., Yang, P. C., Grossman, L., Paleru, A., Xin, V., Tiwari, A., Shafer, R. W., Geng, L. N. 2024; 12 (12)

  Abstract

  COVID-19 vaccinations reduce the severity and number of symptoms for acute SARS-CoV-2 infections and may reduce the risk of developing Long COVID, also known as post-acute sequelae of SARS-CoV-2 (PASC). Limited and heterogenous data exist on how these vaccinations received after COVID-19 infection might impact the symptoms and trajectory of PASC, once persistent symptoms have developed.We investigated the association of post-COVID-19 vaccination with any SARS-CoV-2 vaccine(s) on PASC symptoms in two independent cohorts: a retrospective chart review of self-reported data from patients (n = 128) with PASC seen in the Stanford PASC Clinic between May 2021 and May 2022 and a 2023 multinational survey assessment of individuals with PASC (n = 484).Within the PASC Clinic patient cohort (n = 128), 58.6% (n = 75) were female, and 41.4% (n = 53) were male; 50% (n = 64) were white, and 38.3% (n = 49) were non-white. A total of 60.2% (n = 77) of PASC Clinic patients reported no change in their PASC symptoms after vaccination, 17.2% (n = 22) reported improved symptoms, and 22.7% (n = 29) reported worsened symptoms. In the multinational survey cohort (n = 484), 380 were from the U.S., and 104 were from outside the U.S.; 88.4% (n = 428) were female, and 11.6% (n = 56) were male; and 88.8% (n = 430) were white, and 11.2% (n = 54) were non-white. The distribution of survey self-reported vaccine effects on PASC symptoms was 20.2% worsened (n = 98), 60.5% no effect (n = 293), and 19.2% improved (n = 93). In both cohorts, demographic features, including age, sex, and race/ethnicity, were not significantly associated with post-vaccination PASC symptom changes. There was also a non-significant difference in the median dates of COVID-19 infection among the different outcomes. BMI was significant for symptom improvement (p = 0.026) in the PASC Clinic cohort, while a history of booster doses was significant for symptom improvement (p < 0.001) in the survey cohort.Most individuals with PASC did not report significant changes in their overall PASC symptoms following COVID-19 vaccinations received after PASC onset. Further research is needed to better understand the relationship between COVID-19 vaccinations and PASC.

  View details for DOI 10.3390/vaccines12121427

  View details for PubMedID 39772087

• Post-COVID-19 Vaccination and Long COVID: Insights from Patient-Reported Data VACCINES Quach, T. C., Miglis, M. G., Tian, L., Bonilla, H., Yang, P. C., Grossman, L., Paleru, A., Xin, V., Tiwari, A., Shafer, R. W., Geng, L. N. 2024; 12 (12)

  View details for DOI 10.3390/vaccines12121427

  View details for Web of Science ID 001385630200001