Luisa Fernanda Valenzuela Riveros

All Publications

• Trabecular Bone Score (TBS) varies with correction for tissue thickness versus body mass index; Implications when using pediatric reference norms. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research Valenzuela Riveros, L. F., Long, J., Bachrach, L. K., Leonard, M. B., Kent, K. 2023

  Abstract

  Trabecular bone score (TBS) derived from secondary analysis of lumbar spine DXA scans improves fracture prediction independent of BMD in adults. The utility of TBS to assess fracture risk in younger patients has not been established because pediatric norms have been lacking. Robust TBS reference data from the Bone Mineral Density in Childhood Study (BMDCS) have been published. TBS values for the BMDCS study were derived using an algorithm that accounts for tissue thickness (TBSTH ) rather than the commercially-available algorithm that adjusts for BMI (TBSBMI ). We examined the magnitude of differences in TBSTH and TBSBMI in a cohort of 189 healthy youth. TBS values using both algorithms increased with age and pubertal development in a similar pattern. However,TBSBMI values were systematically and significantly higher than TBSTH (mean=0.06, p<0.0001). The difference between calculated TBSBMI and TBSTH was not uniform. Differences were greater at lower TBS values, in males, in older individuals, in those at later Tanner stages and in those with a greater BMI Z-score. These systematic differences preclude the development of a simple formula to allow conversion of TBSBMI to TBSTH "equivalents". Because of these systematic differences in these two algorithms, using an individual's TBSBMI to calculate a Z-score using the BMDCS TBSTH reference values results in a falsely higher TBS Z-score (differences mean=0.73, IQR=0.3 to 1.6). Until TBSTH software for Hologic DXA equipment becomes commercially available, BMDCS TBS reference norms should not be used. This article is protected by copyright. All rights reserved.

  View details for DOI 10.1002/jbmr.4786

  View details for PubMedID 36779634

• 50 Years Ago in TheJournalofPediatrics: Advances in Neonatal Thyrotoxicosis. The Journal of pediatrics Valenzuela Riveros, L. F., Maahs, D. M. 2021; 231: 199

  View details for DOI 10.1016/j.jpeds.2020.11.030

  View details for PubMedID 33766296

• Parent Perceptions and Experiences Regarding Medication Education at Time of Hospital Discharge for Children With Medical Complexity. Hospital pediatrics Gold, J. M., Chadwick, W., Gustafson, M., Valenzuela Riveros, L. F., Mello, A., Nasr, A. 2020; 10 (8): 679–86

  Abstract

  BACKGROUND: Children with medical complexity (CMC) often require complex medication regimens. Medication education on hospital discharge should provide a critical safety check before medication management transitions from hospital to family. Current discharge processes may not meet the needs of CMC and their families. The objective of this study is to describe parent perspectives and priorities regarding discharge medication education for CMC.METHODS: We performed a qualitative, focus-group-based study, using ethnography. Parents of hospitalized CMC were recruited to participate in 1 of 4 focus groups; 2 were in Spanish. Focus groups were recorded, transcribed, and then coded and organized into themes by using thematic analysis.RESULTS: Twenty-four parents participated in focus groups, including 12 native English speakers and 12 native Spanish speakers. Parents reported a range of 0 to 18 medications taken by their children (median 4). Multiple themes emerged regarding parental ideals for discharge medication education: (1) information quality, including desire for complete, consistent information, in preferred language; (2) information delivery, including education timing, and delivery by experts; (3) personalization of information, including accounting for literacy of parents and level of information desired; and (4) self-efficacy, or education resulting in parents' confidence to conduct medical plans at home.CONCLUSIONS: Parents of CMC have a range of needs and preferences regarding discharge medication education. They share a desire for high-quality education provided by experts, enabling them to leave the hospital confident in their ability to care for their children once home. These perspectives could inform initiatives to improve discharge medication education for all patients, including CMC.

  View details for DOI 10.1542/hpeds.2020-0078

  View details for PubMedID 32737165