Bio


General interests: Interventional oncology, venous disease, portal hypertension, women's health

Completed her Integrated Interventional Radiology Residency at Stanford University. Practiced diagnostic and interventional radiology for a private practice medical group following residency in San Francisco prior to returning to Stanford.

Education:
Trinity University | San Antonio, TX| B.S. Neuroscience
Boston University School of Medicine | M.D, May 2017
Stanford General Surgery Internship
Stanford Integrated Interventional Radiology Residency | 2018-2023

Medical Board of California License

Diagnostic Radiology Junior Chief Resident
2020-2021

Head instructor of the Imageā€guided Interventions RAD203 medical student course
Interventional Radiology Mentor for the Stanford Navigating Medicine Mentors

Moderator and speaker at multiple national conferences at SIR, SIO, RSNA, ACS Quality and Safety

Publications:
-Case series of precision delivery of methylprednisolone in pediatric inflammatory bowel disease:
Feasibility, clinical outcomes, and identification of vasculitits transcriptional program. S Levitte, R
Yarani, A Ganguly, L Martin, J Gubatan, H Nadel, R Gugig, A Syed, A Goyal, KT Park, AThakor.
2023;12(6), 2386.
- Martin LN, Higgins L, Mohabir P, Sze DY, Hofmann LV. Bronchial artery embolization for
hemoptysis in cystic fibrosis patients: a 17-year review. Journal of Vascular and Interventional
Radiology. 2020 Feb 1;31(2):331-5.
- Bettinger LN, Waters LM, Reese SW, Kutner SE, Jacobs DI. Comparative Study of Prepectoral
and Subpectoral Expander-Based Breast Reconstruction and Clavien IIIb Score Outcomes. Plastic
and Reconstructive Surgery Global Open. 2017;5(7):e1433. doi:10.1097/GOX.0000000000001433.
- Eliason NL, Martin L, Low MJ, Sharpe AL. Melanocortin receptor agonist melanotan-II
microinjected in the nucleus accumbens decreases appetitive and consumptie responding for food.
bioRxiv. 2022 Jan 1.
- Sharpe, AL, Varela, E, Bettinger, L, & Beckstead, MJ. Methamphetamine self-administration in
mice decreases GIRK channel-mediated currents in midbrain dopamine neurons. International
Journal of Neuropsychopharmacology. 2015;18(5), pyu073.

Completed academic programs
Clinical Teaching Seminar Series, Honors Scholar
Residency Leadership Through Design
Society of Interventional Oncology, Interventional Oncology Essentials Scholarship and Program
Radiology Society of North America/American Roentgen Ray Society: Intro to Academic Radiology Program

Clinical Focus


  • Vascular and Interventional Radiology

Academic Appointments


  • Clinical Instructor, Radiology

Professional Education


  • Residency: Stanford University Radiology Residency (2023) CA
  • Internship: Stanford University Dept of General Surgery (2018) CA
  • Medical Education: Boston University School of Medicine (2017) MA

All Publications


  • Case Series of Precision Delivery of Methylprednisolone in Pediatric Inflammatory Bowel Disease: Feasibility, Clinical Outcomes, and Identification of a Vasculitic Transcriptional Program. Journal of clinical medicine Levitte, S., Yarani, R., Ganguly, A., Martin, L., Gubatan, J., Nadel, H. R., Franc, B., Gugig, R., Syed, A., Goyal, A., Park, K. T., Thakor, A. S. 2023; 12 (6)

    Abstract

    Systemic steroid exposure, while useful for the treatment of acute flares in inflammatory bowel disease (IBD), is associated with an array of side effects that are particularly significant in children. Technical advancements have enabled locoregional intraarterial steroid delivery directly into specific segments of the gastrointestinal tract, thereby maximizing tissue concentration while limiting systemic exposure. We investigated the feasibility of intraarterial steroid administration into the bowel in a cohort of nine pediatric patients who had IBD. This treatment approach provided symptom relief in all patients, with sustained relief (>2 weeks) in seven out of nine; no serious adverse effects occurred in any patient. In addition, we identified patterns of vascular morphologic changes indicative of a vasculopathy within the mesenteric circulation of inflamed segments of the bowel in pediatric patients with Crohn's disease, which correlated with disease activity. An analysis of publicly available transcriptomic studies identified vasculitis-associated molecular pathways activated in the endothelial cells of patients with active Crohn's disease, suggesting a possible shared transcriptional program between vasculitis and IBD. Intraarterial corticosteroid treatment is safe and has the potential to be widely accepted as a locoregional approach for therapy delivery directly into the bowel; however, this approach still warrants further consideration as a short-term "bridge" between therapy transitions for symptomatic IBD patients with refractory disease, as part of a broader steroid-minimizing treatment strategy.

    View details for DOI 10.3390/jcm12062386

    View details for PubMedID 36983386

  • Bronchial Artery Embolization for Hemoptysis in Cystic Fibrosis Patients: A 17-Year Review. Journal of vascular and interventional radiology : JVIR Martin, L. N., Higgins, L., Mohabir, P., Sze, D. Y., Hofmann, L. V. 2019

    Abstract

    PURPOSE: To review safety and efficacy of bronchial artery embolization (BAE) for treatment of hemoptysis in adult patients with cystic fibrosis (CF) and to report 30-day, 1-year, and 3-year outcomes.MATERIALS AND METHODS: Between January 2001 and April 2018, 242 patients with CF were evaluated for hemoptysis. Thirty-eight BAEs were performed in 28 patients with hemoptysis. Technical success was defined as freedom from repeat embolization and hemoptysis-related mortality. Clinical success was defined as freedom from repeat embolization and mortality from any cause. Technical and clinical success were examined at 30 days, 1 year, and 3 years after initial BAE. Mean patient age was 32 years, and median follow-up was 4.8 years (range, 10 mo to 16.7 y).RESULTS: Technical and clinical success rates at 30 days were 89% (25/28) and 82% (23/28), respectively. Success rates at 1 year were 86% (24/28) and 79% (22/28), respectively, and at 3 years were 82% (23/28) and 75% (21/28), respectively. The 30-day overall complication rate was 7.9% (3/38) with 2.6% (1/38) major complication rate and 5.2% (2/38) minor complication rate. Overall 3-year mortality rate was 25% (7/28).CONCLUSIONS: BAE is safe and effective in patients with CF presenting with life-threatening hemoptysis. BAE results in high rates of long-term technical and clinical success in this patient population despite progressive chronic disease. Repeat embolization is necessary only in a minority of patients.

    View details for DOI 10.1016/j.jvir.2019.08.028

    View details for PubMedID 31899109