Samuel Mireles

All Publications

• Novel Utilization of Strand-Specific Reverse Transcription Polymerase Chain Reaction in Perioperative Clinical Decision Making for SARS-CoV-2 Polymerase Chain Reaction Positive Patients. Paediatric anaesthesia Jette, C. G., Wang, T., Wang, E., Man, J. Y., Mireles, S., Maass, B., Mathew, R., Pinsky, B. A., Claure, R., D'Souza, G. 2022

  Abstract

  In order to prevent in-hospital transmission and potential complications related to SARS-CoV-2 in the perioperative patient, most healthcare institutions require preoperative testing for SARS-CoV-2 prior to proceeding with elective surgery. The Centers for Disease Control and Prevention (CDC) recommends a time and symptom-based duration of isolation for the presumed infectious period. The guidance to avoid retesting of asymptomatic patients in the 90days following a positive reverse transcription polymerase chain reaction (RT-PCR) test is because of the possibility of detection of non-infectious viral shedding. When to reschedule asymptomatic patients who test RT-PCR positive for SARS-CoV-2 preoperatively is of considerable debate, both from the perspective of ensuring a patient's full preoperative fitness, as well as reducing the risk of viral transmission within the hospital. We describe the novel perioperative use of a strand-specific assay to detect minus strand ribonucleic acid (RNA) in a clinical decision-making algorithm to determine optimal timing of elective surgery after a patient tests RT-PCR positive for SARS-CoV-2. This is the first description in the literature of an attempt to further stratify patients who repeatedly test positive for SARS-CoV-2 into infectious versus non-infectious for perioperative planning.

  View details for DOI 10.1111/pan.14448

  View details for PubMedID 35338765

• Undiagnosed Type IIIc Gaucher Disease in a Child With Aortic and Mitral Valve Calcification: Perioperative Complications After Cardiac Surgery JOURNAL OF CARDIOTHORACIC AND VASCULAR ANESTHESIA Mireles, S. A., Seybold, J., Williams, G. 2010; 24 (3): 471-474

  View details for DOI 10.1053/j.jvca.2009.05.006

  View details for Web of Science ID 000278288500017

  View details for PubMedID 19632857

• A POOR CORRELATION EXISTS BETWEEN OSCILLOMETRIC AND RADIAL ARTERIAL BLOOD PRESSURE AS MEASURED BY THE PHILIPS MP90 MONITOR JOURNAL OF CLINICAL MONITORING AND COMPUTING Mireles, S. A., Jaffe, R. A., Drover, D. R., Brock-Utne, J. G. 2009; 23 (3): 169-174

  Abstract

  In anesthesia and critical care, invasive arterial blood pressure monitoring is the gold standard against which other methods of monitoring are compared. In this assessment of the Philips MP90 monitor, the objective was to determine whether or not oscillometric measurements were within the accuracy standards set by the Association for the Advancement of Medical Instrumentation (AAMI) and the British Hypertension Society (BHS). Three hundred and one invasive and noninvasive paired measurements were obtained from eleven adult patients on the neurosurgical service at Stanford University Medical Center. Bland-Altman plots were created to assess agreement between the two measurement systems. Paired correlation analysis, bias and precision calculations were performed. Oscillometric blood pressure measurements correlated with arterial measurements yielding Pearson r values of 0.68, 0.67 and 0.62 for systolic, diastolic and mean pressures, respectively (P < 0.01.) Mean differences with 95% confidence intervals were -3.8 mmHg +/- 13.6, -2.4 mmHg +/- 10.0, and 4.0 mmHg +/- 13.1 for systolic, diastolic and mean pressures, respectively. The mean difference for these measurements was

  View details for DOI 10.1007/s10877-009-9178-8

  View details for PubMedID 19396553

• Anesthetic implications of a near-lethal sodium azide exposure ANESTHESIA AND ANALGESIA Angelotti, T., Mireles, S., McMahon, D. 2007; 104 (1): 229-230

  View details for DOI 10.1213/01.ane.0000249841

  View details for Web of Science ID 000243040100085

  View details for PubMedID 17179300