Familiar growth factors have diverse roles in neural network assembly.
Current opinion in neurobiology
2021; 66: 233–39
The assembly of neuronal circuits during development depends on guidance of axonal growth cones by molecular cues deposited in their environment. While a number of families of axon guidance molecules have been identified and reviewed, important and diverse activities of traditional growth factors are emerging. Besides clear and well recognized roles in the regulation of cell division, differentiation and survival, new research shows later phase roles for a number of growth factors in promoting neuronal migration, axon guidance and synapse formation throughout the nervous system.
View details for DOI 10.1016/j.conb.2020.12.016
View details for PubMedID 33477094