
Michael Lennig
Clinical Assistant Professor, Anesthesiology, Perioperative and Pain Medicine
Clinical Focus
- Anesthesia
- Pediatric Anesthesia
- Pediatric Cardiac Anesthesia
Honors & Awards
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Teacher of the Year, Stanford University School of Medicine, Division of Pediatric Anesthesiology (2020-21)
Professional Education
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Medical Education: The Ohio State University College of Medicine (2011) OH
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Residency: University of Cincinnati College of Medicine (2015) OH
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Fellowship: Stanford University Pediatric Anesthesia Fellowship (2016) CA
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Fellowship/Advanced Training, Stanford University - Dept of Ped Anesthesia, Pediatric Cardiac Anesthesiology (2017)
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Board Certification: American Board of Anesthesiology, Anesthesia (2016)
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Board Certification: American Board of Anesthesiology, Pediatric Anesthesia (2017)
All Publications
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Acute Hemodynamics in the Fontan Circulation: Open-Label Study of Vasopressin.
Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies
2023
Abstract
OBJECTIVE: To describe the acute hemodynamic effect of vasopressin on the Fontan circulation, including systemic and pulmonary pressures and resistances, left atrial pressure, and cardiac index.DESIGN: Prospective, open-label, nonrandomized study (NCT04463394).SETTING: Cardiac catheterization laboratory at Lucile Packard Children's Hospital, Stanford.PATIENTS: Patients 3-50 years old with a Fontan circulation who were referred to the cardiac catheterization laboratory for hemodynamic assessment and/or intervention.INTERVENTIONS: A 0.03 U/kg IV (maximum dose 1 unit) bolus of vasopressin was administered over 5 minutes, followed by a maintenance infusion of 0.3 mU/kg/min (maximum dose 0.03 U/min).MEASUREMENTS AND MAIN RESULTS: Comprehensive cardiac catheterization measurements before and after vasopressin administration. Measurements included pulmonary artery, atrial, and systemic arterial pressures, oxygen saturations, and systemic and pulmonary flows and resistances. There were 28 patients studied. Median age was 13.5 (9.1, 17) years, and 16 (57%) patients had a single or dominant right ventricle. Following vasopressin administration, systolic blood pressure and systemic vascular resistance (SVR) increased by 17.5 (13.0, 22.8) mm Hg (Z value -4.6, p < 0.001) and 3.8 (1.8, 7.5) Wood Units (Z value -4.6, p < 0.001), respectively. The pulmonary vascular resistance (PVR) decreased by 0.4±0.4 WU (t statistic 6.2, p < 0.001), and the left atrial pressure increased by 1.0 (0.0, 2.0) mm Hg (Z value -3.5, p < 0.001). The PVR:SVR decreased by 0.04±0.03 (t statistic 8.1, p < 0.001). Neither the pulmonary artery pressure (median difference 0.0 [-1.0, 1.0], Z value -0.4, p = 0.69) nor cardiac index (0.1±0.3, t statistic -1.4, p = 0.18) changed significantly. There were no adverse events.CONCLUSIONS: In Fontan patients undergoing cardiac catheterization, vasopressin administration resulted in a significant increase in systolic blood pressure, SVR, and left atrial pressure, decrease in PVR, and no change in cardiac index or pulmonary artery pressure. These findings suggest that in Fontan patients vasopressin may be an option for treating systemic hypotension during sedation or general anesthesia.
View details for DOI 10.1097/PCC.0000000000003326
View details for PubMedID 37462430
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Transnasal Humidified Rapid Insufflation Ventilatory Exchange (THRIVE) augments oxygenation in children with cyanotic heart disease during microdirect laryngoscopy and bronchoscopy
JOURNAL OF CLINICAL ANESTHESIA
2019; 56: 53–54
View details for DOI 10.1016/j.jclinane.2019.01.029
View details for Web of Science ID 000468713500021
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Assessment of the Reconstructed Pulmonary Circulation With Lung Perfusion Scintigraphy After Unifocalization and Repair of Tetralogy of Fallot With Major Aortopulmonary Collaterals
WORLD JOURNAL FOR PEDIATRIC AND CONGENITAL HEART SURGERY
2019; 10 (3): 313–20
View details for DOI 10.1177/2150135119836735
View details for Web of Science ID 000470668700010