Naola S. Austin M.D., is a Clinical Assistant Professor in the Department of Anesthesiology, Perioperative and Pain Medicine at Stanford University and the Veterans Affairs Palo Alto Health Care System. She is teaching faculty at the Center for Immersive and Simulation-based Learning, OB SIM Team, and VA Palo Alto.
She is originally from Santa Fe, NM and received her medical degree at Weill Cornell Medical College in New York, NY. After completing residency training in Anesthesiology at the University of Washington, she went on to dual fellowship training in Obstetric Anesthesia and Healthcare Simulation.
In addition to her work as a Co-Primary Investigator with the Safety Learning Lab, she has published basic science articles on synapse biology, clinical reviews on cervical spine injury in trauma and burns, and Simulation and Communication in Obstetric care. She has received multiple honors including U.S.-E.U. Exchange Scholar Rogers’ Colloquium Speaker, Resident of the Year, and Foundation for Anesthesia Education & Research Scholar.
Naola is an avid gardener, leisure cyclist, and very amateur rock climber.
Clinical Assistant Professor, Anesthesiology, Perioperative and Pain Medicine
Internship: University of Washington Anesthesiology and Pain Medicine Residency WA
Fellowship: Stanford University (2015)
Board Certification: Anesthesia, American Board of Anesthesiology (2014)
Medical Education: Weill Cornell Medical College (2009) NY
Residency: University of Washington WA
Fellowship: Stanford University CA
- Correlation of changes in hemodynamic response as measured by cerebral optical spectrometry with subjective pain ratings in volunteers and patients: a prospective cohort study JOURNAL OF PAIN RESEARCH 2018; 11: 1991–98
Building Comprehensive Strategies for Obstetric Safety: Simulation Drills and Communication.
Anesthesia and analgesia
2016; 123 (5): 1181-1190
As pioneers in the field of patient safety, anesthesiologists are uniquely suited to help develop and implement safety strategies to minimize preventable harm on the labor and delivery unit. Most existing obstetric safety strategies are not comprehensive, lack input from anesthesiologists, are designed with a relatively narrow focus, or lack implementation details to allow customization for different units. This article attempts to address these gaps and build more comprehensive strategies by discussing the available evidence and multidisciplinary authors' local experience with obstetric simulation drills and optimization of team communication.
View details for PubMedID 27749353
National and International Guidelines for Patient Blood Management in Obstetrics: A Qualitative Review.
Anesthesia and analgesia
In developed countries, rates of postpartum hemorrhage (PPH) requiring transfusion have been increasing. As a result, anesthesiologists are being increasingly called upon to assist with the management of patients with severe PPH. First responders, including anesthesiologists, may adopt Patient Blood Management (PBM) recommendations of national societies or other agencies. However, it is unclear whether national and international obstetric societies' PPH guidelines account for contemporary PBM practices. We performed a qualitative review of PBM recommendations published by the following national obstetric societies and international groups: the American College of Obstetricians and Gynecologists; The Royal College of Obstetricians and Gynecologists, United Kingdom; The Royal Australian and New Zealand College of Obstetricians and Gynecologists; The Society of Obstetricians and Gynecologists of Canada; an interdisciplinary group of experts from Austria, Germany, and Switzerland, an international multidisciplinary consensus group, and the French College of Gynaecologists and Obstetricians. We also reviewed a PPH bundle, published by The National Partnership for Maternal Safety. On the basis of our review, we identified important differences in national and international societies' recommendations for transfusion and PBM. In the light of PBM advances in the nonobstetric setting, obstetric societies should determine the applicability of these recommendations in the obstetric setting. Partnerships among medical, obstetric, and anesthetic societies may also help standardize transfusion and PBM guidelines in obstetrics.
View details for PubMedID 27557476
Airway management in cervical spine injury.
International journal of critical illness and injury science
2014; 4 (1): 50-56
To minimize risk of spinal cord injury, airway management providers must understand the anatomic and functional relationship between the airway, cervical column, and spinal cord. Patients with known or suspected cervical spine injury may require emergent intubation for airway protection and ventilatory support or elective intubation for surgery with or without rigid neck stabilization (i.e., halo). To provide safe and efficient care in these patients, practitioners must identify high-risk patients, be comfortable with available methods of airway adjuncts, and know how airway maneuvers, neck stabilization, and positioning affect the cervical spine. This review discusses the risks and benefits of various airway management strategies as well as specific concerns that affect patients with known or suspected cervical spine injury.
View details for DOI 10.4103/2229-5151.128013
View details for PubMedID 24741498
View details for PubMedCentralID PMC3982371
A high-throughput method for generating uniform microislands for autaptic neuronal cultures
JOURNAL OF NEUROSCIENCE METHODS
2011; 198 (2): 230-235
Generating microislands of culture substrate on coverslips by spray application of poly-d lysine is a commonly used method for culturing isolated neurons that form self (autaptic) synapses. This preparation has multiple advantages for studying synaptic transmission in isolation; however, generating microislands by spraying produces islands of non-uniform size and thus cultures vary widely in the number of islands containing single neurons. To address these problems, we developed a high-throughput method for reliably generating uniformly shaped microislands of culture substrate. Stamp molds formed of poly(dimethylsiloxane) (PDMS) were fabricated with arrays of circles and used to generate stamps made of 9.2% agarose. The agarose stamps were capable of loading sufficient poly D-lysine and collagen dissolved in acetic acid to rapidly generate coverslips containing at least 64 microislands per coverslip. When hippocampal neurons were cultured on these coverslips, there were significantly more single-neuron islands per coverslip. We noted that single neurons tended to form one of three distinct neurite-arbor morphologies, which varied with island size and the location of the cell body on the island. To our surprise, the number of synapses per autaptic neuron did not correlate with arbor shape or island size, suggesting that other factors regulate the number of synapses formed by isolated neurons. The stamping method we report can be used to increase the number of single-neuron islands per culture and aid in the rapid visualization of microislands.
View details for DOI 10.1016/j.jneumeth.2011.04.012
View details for Web of Science ID 000292435900010
View details for PubMedID 21515305
View details for PubMedCentralID PMC3641143
Synaptic vesicle protein 2 enhances release probability at quiescent synapses
JOURNAL OF NEUROSCIENCE
2006; 26 (4): 1303-1313
We report a thorough analysis of neurotransmission in cultured hippocampal neurons lacking synaptic vesicle protein 2 (SV2), a membrane glycoprotein present in all vesicles that undergo regulated secretion. We found that SV2 selectively enhances low-frequency neurotransmission by priming morphologically docked vesicles. Loss of SV2 reduced initial release probability during a train of action potentials but had no effect on steady-state responses. The amount and decay rate of asynchronous release, two measures sensitive to presynaptic calcium concentrations, are not altered in SV2 knock-outs, suggesting that SV2 does not act by modulating presynaptic calcium. Normal neurotransmission could be temporarily recovered by delivering an exhaustive stimulus train. Our results indicate that SV2 primes vesicles in quiescent neurons and that SV2 function can be bypassed by an activity-dependent priming mechanism. We propose that SV2 action modulates synaptic networks by ensuring that low-frequency neurotransmission is faithfully conveyed.
View details for DOI 10.1523/JNEUROSCI.2699-05.2006
View details for Web of Science ID 000234896200029
View details for PubMedID 16436618