Contact

  • Academic
    nneoman@stanford.edu
    University - Student Department: Chemistry Position: Undergraduate
    University - Student Department: African and African American Studies Position: Undergraduate
    University - Student Department: Biology Position: Graduate

Additional Info

All Publications

  • Inflammatory Pathways and the Bone Marrow Microenvironment in Inherited Bone Marrow Failure Syndromes. Stem cells (Dayton, Ohio) Neoman, N., Kim, H. N., Viduya, J., Goyal, A., Liu, Y. L., Sakamoto, K. M. 2025

    Abstract

    Inherited Bone Marrow Failure Syndromes (IBMFS) are a diverse group of genetic disorders characterized by insufficient hematopoietic cell production due to blood stem cell dysfunction. The most common syndromes are Fanconi Anemia, Diamond-Blackfan Anemia, and Shwachman-Diamond Syndrome. These conditions share a theme of chronically producing pro-inflammatory cytokines such as TNF-α, IL-1β, IL-6, TGF-β, IFN-I, and IFN-γ. Each of these cytokines can impact the bone marrow microenvironment and drive the pathophysiology of IBMFS. This review aims to provide the latest progress in the field regarding the mechanistic underpinnings of inflammation in these IBMFS, as well as the effect of inflammation on the bone marrow microenvironment. A comprehensive understanding of the inflammation in IBMFS will open new avenues for intervention to restore bone marrow stability and improve patient prognosis. Future research must include targeting these mechanisms to develop novel therapies that can potentially mitigate the effects of chronic inflammation in IBMFS.

    View details for DOI 10.1093/stmcls/sxaf021

    View details for PubMedID 40296192

  • A Novel Mouse Model to Study the Effects of New Therapies for Diamond Blackfan Anemia. Blood advances Liu, Y. L., Neoman, N., Sakamoto, K. M. 2025

    View details for DOI 10.1182/bloodadvances.2024015119

    View details for PubMedID 39913921

  • Disease Correction of a Diamond-Blackfan Anemia Mouse Model Using Non-Genotoxic Conditioning and Hematopoietic Stem Cell Transplantation Swartzrock, L., Liu, Y., Hoang, H., Ho, K., Neoman, N., Krampf, M. R., Sakamoto, K. M., Czechowicz, A. D. ELSEVIER. 2024: 194-195

    View details for DOI 10.1182/blood-2024-205659

    View details for Web of Science ID 001457401600044

  • Novel Mouse Model That Recapitulates the Hematologic Phenotype of Diamond Blackfan Anemia Liu, Y., Wang, N., Neoman, N., Wong, C., Glader, B., Doty, R. T., Wilkes, M. C., Abkowitz, J. L., Sakamoto, K. M. AMER SOC HEMATOLOGY. 2023

    View details for DOI 10.1182/blood-2023-187734

    View details for Web of Science ID 001159306703213

https://orcid.org/0009-0002-2393-321X