Nichole Tyson MD is a Clinical Associate Professor of Obstetrics and Gynecology at Stanford University School of Medicine. She specializes in Pediatric and Adolescent Gynecology (PAG). For over 20 years, Dr. Tyson has partnered with girls and their families as they journey from childhood through adolescence and into adulthood. Dr. Tyson enjoys solving complex problems as well as common concerns that can be overlooked and challenging to girls and young women. She is been recognized locally and nationally as a leader in the field and skilled and experienced surgeon caring for patients with endometriosis, adnexal masses and variations in urogenital anatomy.
As a Pediatric and Adolescent Gynecologist, she specializes in problems such as abnormal periods, hormone management and adolescent contraception in people with underlying medical conditions, pelvic masses, differences of sex development and complex utero-vaginal anatomy.
She has been active on a number of national medical committees, including chair of the North American Society of Pediatric and Adolescent Gynecology (NASPAG) Education committee, Advocacy committee, Board of Directors, member of ACOGs Adolescent committee and a long-standing member of ACOGs LARC work group. She is an active contributor to the peer reviewed literature in pediatric and adolescent gynecology. Dr. Tyson also has extensive experience with the consumer press as an adolescent gynecology expert for numerous online articles in such magazines as Seventeen, Self and NY Times. She has been recognized for her teaching having won the UC Davis residency teaching award numerous times and locally recognized as winning Sacramento Magazine top doctor several times.
Dr. Tyson is a premier educator serving as faculty for a national advanced laparoscopic surgery course for nearly 10 years, presenting at numerous national and international conferences and a creative author of emodules and video webinars for educating fellow physicians. She has also been a telehealth pioneer and developed and and co-hosts the Journal of Pediatric and Adolescent Gynecology podcast.

Clinical Focus

  • Pediatric Adolescent Gynecology
  • Obstetrics and Gynecology

Academic Appointments

Administrative Appointments

  • Gynecology Clerkship Director, Stanford University School of Medicine (2021 - Present)
  • Section Lead, Hematology & Gynecology Joint Clinic, Stanford University School of Medicine, Lucile Packard Children’s Hospital (2021 - Present)
  • Chair, Pediatric & Adolescent Subspecialty Group, Kaiser Permanente, Northern California (2015 - 2020)
  • Director, Obstetrics & Gynecology Teen Clinic, Kaiser Permanente, Northern California (1999 - 2020)
  • Lead, Family Planning, International Collaborative, Kaiser Permanente, Northern California (2018 - 2020)
  • Women's Health Liaison, Kaiser Permanente, Sacramento Region (2016 - 2020)

Honors & Awards

  • Outstanding Residency Teaching Award, University of California, Davis (2016, 2019)
  • Presidents Award, North American Society of Pediatric & Adolescent Gynecology (NASPAG) (2018)
  • Top Doctors, Sacramento Magazine (2007, 2016, 2017, 2020)

Boards, Advisory Committees, Professional Organizations

  • Annual Clinical Meeting Sponsored Workshop Chair, North American Society for Pediatric and Adolescent Gynecology (2020 - Present)
  • Advocacy Committee Chair, North American Society for Pediatric and Adolescent Gynecology (2019 - Present)
  • Wellness Committee, ACOG District IX (2020 - Present)
  • Social Media Committee, North American Society for Pediatric and Adolescent Gynecology (2018 - Present)
  • LARC Work Group, American College of Obstetrics and Gynecology (2013 - Present)
  • International Task Force, North American Society for Pediatric and Adolescent Gynecology (2019 - Present)
  • Annual Clinical Meeting Program commitee, North American Society for Pediatric and Adolescent Gynecology (2018 - Present)
  • Development committee, North American Society for Pediatric and Adolescent Gynecology (2019 - Present)
  • Education, Website, Membership Committees, North American Society for Pediatric and Adolescent Gynecology (2013 - 2017)
  • Editorial Board, Journal of Pediatric and Adolescent Gynecology (2014 - Present)
  • Board member at large, North American Society for Pediatric and Adolescent Gynecology (2017 - 2020)
  • Education Committee Chair, North American Society for Pediatric and Adolescent Gynecology (2017 - 2019)
  • Fellow, American College of Obstetrics and Gynecology (2002 - Present)
  • Adolescent Committee, American College of Obstetrics and Gynecology (2004 - 2007)
  • Affiliate fellow, Society of Family Planning (2012 - Present)
  • Member, American Medical Association (1999 - Present)
  • Member, American Medical Women's Association (2020 - Present)
  • Medical Student President, American Medical Women's Association (1994 - 1995)
  • Medical Student Vice President, American Medical Women's Association (1993 - 1994)

Professional Education

  • Focused Practice Designation, American Board of Obstetrics and Gynecology, Pediatric and Adolescent Gynecology (2018)
  • Board Certification: American Board of Obstetrics and Gynecology, Obstetrics and Gynecology Designation (2019)
  • Board Certification, American Board of Obstetrics and Gynecology, American Board of Obstetrics and Gynecology, Obstetrics and Gynecology (2001)
  • Residency: UC Davis Dept of OB/Gyn (1999) CA
  • Residency, University of California, Davis, Obstetrics and Gynecology (1999)
  • Medical Education: Tufts University School of Medicine (1995) MA
  • Medical Education, Tufts University School of Medicine, Boston, Massachusetts (1995)

Research Interests

  • Adolescence
  • Professional Development

All Publications

  • NASPAG/SAHM Statement: The 21st Century Cures Act and Adolescent Confidentiality. Journal of pediatric and adolescent gynecology Carlson, J., Goldstein, R., Hoover, K., Tyson, N. 2021; 34 (1): 3–5

    View details for DOI 10.1016/j.jpag.2020.12.015

    View details for PubMedID 33485521

  • NASPAG/SAHM Statement: The 21st Century Cures Act and Adolescent Confidentiality. The Journal of adolescent health : official publication of the Society for Adolescent Medicine Carlson, J., Goldstein, R., Hoover, K., Tyson, N. 2021; 68 (2): 426–28

    View details for DOI 10.1016/j.jadohealth.2020.10.020

    View details for PubMedID 33541602

  • Differential Diagnosis of a Unique Vulvar Mass in an Adolescent. Obstetrics and gynecology Chow, S., Doyle, A., Hammer, P., Tyson, N. A. 2021


    Vulvar masses in adolescents have a broad differential diagnosis, yet few reports exist detailing masses of mammary origin.A nulliparous, healthy 16-year-old adolescent presented with a longstanding, ulcerated, 17-cm vulvar mass of unknown origin and pronounced inguinal lymphadenopathy. The patient underwent a left radical partial vulvectomy, with pathology revealing terminal duct lobular units consistent with polymastia.Differential diagnosis of a vulvar mass in an adolescent should include polymastia.

    View details for DOI 10.1097/AOG.0000000000004563

    View details for PubMedID 34735404

  • Subdermal Contraceptive Implant Insertion Trends and Retention in Adolescents. Journal of pediatric and adolescent gynecology Lopez, M., Merchant, M., Postlethwaite, D., Tyson, N. 2020


    PURPOSE: There is growing advocacy for use of long-acting reversible contraception among sexually active adolescents. Our primary aims were to evaluate etonogestrel subdermal contraceptive implant (SCI) insertion trends among adolescents, as well as SCI retention at 1, 2 and 3 years, indications for removal, and to identify pregnancies occurring during SCI use.METHODS: A retrospective cohort study was conducted of adolescents aged 13-19 with SCI insertions in 2008-2014 within a large integrated healthcare system. Demographic and clinical characteristics included age, race/ethnicity, BMI, gravidity, parity, insertions, reinsertions, indications for removal, and pregnancy. Electronic medical record review was conducted on a randomized sample of 540 adolescents with insertions during 2008-2011 for the retention objective to validate electronically extracted variables. Analyses included descriptive statistics, survival analysis with Kaplan-Meier estimates for implant retention and Cochran-Armitage trend test for insertions by year during 2008-2014.RESULTS: Most adolescent SCI users were non-Hispanic White (43%), or Hispanic (34.2%) and 16 years or older (84.2%) at the time of insertion. Overall, 1-, 2- and 3-year retention rates were 78.6%, 59.4% and 26.2% respectively, with retention at 44.3% at 2 years 9 months (indicative of removal of method for near expiration of 3- year device). The insertion rate trend demonstrated statistically significant increases annually, from 0.14% in 2008 to 0.91% in 2014, p< 0.0001. No pregnancies were documented during implant use. The most common indication for SCI removal was device expiration.CONCLUSIONS: SCI insertions increased annually among adolescents, with more than a six-fold increase over the 6-year study period, and over half of the SCIs retained through 2 years of use.

    View details for DOI 10.1016/j.jpag.2020.12.019

    View details for PubMedID 33388444

  • A Clinical Approach to Catamenial Epilepsy: A Review. The Permanente journal Frank, S., Tyson, N. A. 2020; 24: 1–3


    IMPORTANCE: Catamenial epilepsy (CE) is exacerbated by hormonal fluctuations during the menstrual cycle. Approximately 1.7 million women have epilepsy in the United States. CE affects more than 40% of women with epilepsy. There is a paucity of literature addressing this condition from a clinical standpoint, and the literature that does exist is limited to the neurological community. This article reviews the diagnosis and management of CE for the non-neurologist. Women with CE have early touch points in their care with numerous health care providers before ever consulting with a specialist, including OB/GYNs, pediatricians, emergency department physicians, and family medicine providers. In addition, women affected by CE have seizures that are more recalcitrant to traditional epilepsy treatment regimens. To optimize management in patients affected by CE, menstrual physiology must be understood, individualized hormonal contraception treatment considered, and adjustments and interactions with antiepileptic drugs addressed.OBSERVATIONS: CE is a unique subset of seizure disorders affected by menstrual fluctuations of progesterone and estrogen. The diagnosis of CE has been refined and clarified. There is an ever-increasing understanding of the importance and variety of options of hormonal contraception available to help manage CE. Furthermore, antiepileptic drugs and contraception can interact, so attention must be directed to optimizing both regimens to prevent uncontrolled seizures and pregnancy.CONCLUSION AND RELEVANCE: CE can be diagnosed with charting of menstrual cycles and seizure activity. Hormonal treatments that induce amenorrhea have been shown to reduce CE. Optimizing antiepileptic drug dosing and contraceptive methods also can minimize unplanned pregnancies in women affected by CE.

    View details for DOI 10.7812/TPP/19.145

    View details for PubMedID 33482944

  • Provision of Reproductive Health for Teens During a Pandemic J Pediatr Adolesc Gynecol Tyson, N. 2020; 33 (4): 331
  • Reproductive effects of obesity in adolescents Textbook of Pediatric and Adolescent Gynecology Wellenstein, W., Tyson, N. CRC Press. 2020; second: 256–264.
  • Adolescents and long-acting reversible contraceptives: beyond the basics. Current opinion in obstetrics & gynecology Stanton, T. n., Cizek, S. n., Tyson, N. n. 2020


    The current article explores some of the more complex subtopics concerning adolescents and long-acting reversible contraceptives (LARC).Recent research has highlighted ways in which LARC provision can be optimized in adolescents and has identified gaps in adolescent LARC access and utilization.Contraceptive counseling for adolescents should be patient-centered, not necessarily LARC-first, to avoid coercion. There are increasing applications for the noncontraceptive benefits of LARC for several unique patient populations and medical conditions.

    View details for DOI 10.1097/GCO.0000000000000668

    View details for PubMedID 33002953

  • A clinical approach to catamenial epilepsy Perm J Frank, S. E., Tyson, N. A. 2020; 24 (19)
  • Childhood-Onset Eosinophilic Granulomatosis with Polyangiitis with a Vulvar Granuloma: A Case Report and Review of the Literature. Journal of pediatric and adolescent gynecology Swain, C. A., Sherry, T. R., Tyson, N. n. 2019; 32 (4): 425–28


    Eosinophilic granulomatosis with polyangiitis (EGPA) is a rare multisystem necrotizing vasculitis associated with eosinophilia and extravascular granuloma and classically involving the upper and lower airways. There have only been a few reported cases of gynecologic involvement in EGPA.We present an 8-year-old girl diagnosed with EGPA with a vulvar granuloma in what is, to our knowledge, the first reported pediatric gynecologic manifestation of EGPA. Interestingly, the vulvar granuloma did not respond to initial immunosuppressant treatment with prednisone and methotrexate and required treatment regimen modification with mycophenolate mofetil resulting in granuloma resolution.EGPA in the pediatric population has a relatively high mortality rate compared with in the adult population thus it is important that vulvar granulomas associated with EGPA should be included in the differential diagnosis of a vulvar mass allowing for the prompt diagnosis and treatment of this potentially fatal disease in children.

    View details for DOI 10.1016/j.jpag.2019.03.002

    View details for PubMedID 30904627

  • Reproductive Health: Options, Strategies, and Empowerment of Women. Obstetrics and gynecology clinics of North America Tyson, N. A. 2019; 46 (3): 409–30


    Contraception is paramount to the overall health and longevity of women. Most women in the United States use birth control in their reproductive lifetimes. All options should be available and easily accessible to permit individualization and optimization of chosen methods. Current contraceptive methods available in the United States are reviewed. Emergency contraception, contraception in the postpartum period, and strategies to tailor methods to those affected by partner violence are also addressed. Tables and flow charts help providers and patients compare various contraceptive methods, optimize the start of a method, and identify resources for addressing safety in those with underlying medical conditions.

    View details for DOI 10.1016/j.ogc.2019.04.002

    View details for PubMedID 31378285

  • Childhood and adolescent obesity definitions as related to BMI, evaluation and management options. Best practice & research. Clinical obstetrics & gynaecology Tyson, N. n., Frank, M. n. 2018; 48: 158–64


    In North America, 30% of children are overweight or obese. Child obesity is a precursor to adult health risks. Diagnosis of childhood obesity is difficult. The best measurement is BMI percentile charts. Obesity in children and adolescents can be treated by diet and activity changes. Family involvement in healthy lifestyle changes is best for weight loss and prevention.

    View details for DOI 10.1016/j.bpobgyn.2017.06.003

    View details for PubMedID 28838829

  • HPV Update. Journal of pediatric and adolescent gynecology Tyson, N. n. 2017; 30 (2): 262–64

    View details for DOI 10.1016/j.jpag.2016.10.009

    View details for PubMedID 27989918

  • Committee Opinion No 672: Clinical Challenges of Long-Acting Reversible Contraceptive Methods. Obstetrics and gynecology 2016; 128 (3): e69–77


    Long-acting reversible contraceptive methods are the most effective reversible contraceptives and have an excellent safety record. Although uncommon, possible long-acting reversible contraceptive complications should be included in the informed consent process. Obstetrician-gynecologists and other gynecologic care providers should understand the diagnosis and management of common clinical challenges. The American College of Obstetricians and Gynecologists recommends the algorithms included in this document for management of the most common clinical challenges.

    View details for DOI 10.1097/AOG.0000000000001644

    View details for PubMedID 27548557

  • Laparoscopic Myomectomy of a Symptomatic Uterine Leiomyoma in a 15-Year-Old Adolescent. Journal of pediatric and adolescent gynecology Salehi, P. P., Tyson, N. n. 2016; 29 (6): e87–e90


    Although adnexal masses and ovarian torsion are common causes of acute pain in the female adolescent, fibroids are an uncommon etiology and little is reported in the literature. Because of the rarity of adolescent leiomyomas, the best surgical management is still unknown.To our knowledge, this is the first case report of a laparoscopic myomectomy in the adolescent population. The removed fibroid is one of the largest documented cases of uterine leiomyoma in adolescents.Degenerative fibroids, albeit less common, should be kept on the differential diagnosis, as a possible cause of pelvic mass and pain in the adolescent population. Fibroids in the adolescent patient, like the adult, can be managed with minimally invasive surgery with excellent clinical outcomes.

    View details for DOI 10.1016/j.jpag.2016.05.007

    View details for PubMedID 27262836

  • Contraception Adolescent Medicine Today A Guide to Caring for the Adolescent Patient Tyson, N., Simpson, E., Berlan, E. 2011: 233–253
  • Breast Disorders in Females Adolescent Medicine: the Requisites in Pediatrics Huppert, J., Tyson, N. Mosby Inc. 2008: 146–151
  • Care of the overweight adolescent including polycystic ovarian syndrome. Clinical obstetrics and gynecology Zidenberg, N. n., Wright, S. n. 2008; 51 (2): 249–56


    Obstetrician-gynecologists are responsible for promoting healthy eating and physical activity in adolescents during annual screening examinations. Adolescents with a body mass index for age greater than or equal to the 95th percentile should undergo an in-depth health assessment to determine psychosocial morbidity and risk of cardiovascular disease. Further research is needed to determine the most efficacious approach to the prevention and treatment of obesity in adolescents. For now, it is best to extrapolate an approach from data pertaining to children and adults, while being cognizant of the special psychosocial and physical needs of adolescents.

    View details for DOI 10.1097/GRF.0b013e31816d2282

    View details for PubMedID 18463456