Academic Appointments

All Publications

  • Efficient Radioisotope Energy Transfer by Gold Nanoclusters for Molecular Imaging SMALL Volotskova, O., Sun, C., Stafford, J. H., Koh, A. L., Ma, X., Cheng, Z., Cui, B., Pratx, G., Xing, L. 2015; 11 (32): 4002-4008

    Abstract

    Beta-emitting isotopes Fluorine-18 and Yttrium-90 are tested for their potential to stimulate gold nanoclusters conjugated with blood serum proteins (AuNCs). AuNCs excited by either medical radioisotope are found to be highly effective ionizing radiation energy transfer mediators, suitable for in vivo optical imaging. AuNCs synthesized with protein templates convert beta-decaying radioisotope energy into tissue-penetrating optical signals between 620 and 800 nm. Optical signals are not detected from AuNCs incubated with Technetium-99m, a pure gamma emitter that is used as a control. Optical emission from AuNCs is not proportional to Cerenkov radiation, indicating that the energy transfer between the radionuclide and AuNC is only partially mediated by Cerenkov photons. A direct Coulombic interaction is proposed as a novel and significant mechanism of energy transfer between decaying radionuclides and AuNCs.

    View details for DOI 10.1002/smll.201500907

    View details for Web of Science ID 000360226300016

  • Differential Effects of Cold Atmospheric Plasma in the Treatment of Malignant Glioma Plos One Sui, A., Volotskova, O., Cheng, X., Khasla, S. S., Bian, K., Murad, F., Keidar, M., Sherman, J. H. 2015

    View details for DOI 10.1371/journal.pone.0126313

  • Synergistic Assembly of Heavy Metal Clusters and Luminescent Organic Bridging Ligands in Metal-Organic Frameworks for Highly Efficient X-ray Scintillation JOURNAL OF THE AMERICAN CHEMICAL SOCIETY Wang, C., Volotskova, O., Lu, K., Ahmad, M., Sun, C., Xing, L., Lin, W. 2014; 136 (17): 6171-6174

    Abstract

    We have designed two metal-organic frameworks (MOFs) to efficiently convert X-ray to visible-light luminescence. The MOFs are constructed from M6(μ3-O)4(μ3-OH)4(carboxylate)12 (M = Hf or Zr) secondary building units (SBUs) and anthracene-based dicarboxylate bridging ligands. The high atomic number of Zr and Hf in the SBUs serves as effective X-ray antenna by absorbing X-ray photons and converting them to fast electrons through the photoelectric effect. The generated electrons then excite multiple anthracene-based emitters in the MOF through inelastic scattering, leading to efficient generation of detectable photons in the visible spectrum. The MOF materials thus serve as efficient X-ray scintillators via synergistic X-ray absorption by the metal-cluster SBUs and optical emission by the bridging ligands.

    View details for DOI 10.1021/ja500671h

    View details for Web of Science ID 000335369200006

    View details for PubMedID 24730683

  • Hard X-ray-induced optical luminescence via biomolecule-directed metal clusters CHEMICAL COMMUNICATIONS Osakada, Y., Pratx, G., Sun, C., Sakamoto, M., Ahmad, M., Volotskova, O., Ong, Q., Teranishi, T., Harada, Y., Xing, L., Cui, B. 2014; 50 (27): 3549-3551

    Abstract

    Here, we demonstrate that biomolecule-directed metal clusters are applicable in the study of hard X-ray excited optical luminescence, promising a new direction in the development of novel X-ray-activated imaging probes.

    View details for DOI 10.1039/c3cc48661c

    View details for Web of Science ID 000332483200003

    View details for PubMedID 24463467

  • Cold atmospheric plasma in cancer therapy Physics of Plasmas Keidar, M. n., Shashurin, A. n., Volotskova, O. n., Stepp, M. n., Srinivasan, P. n., Sandler, A. n., Trink, B. n. 2013; 20: 1-8
  • Targeting the cancer cell cycle by cold atmospheric plasma Scientific Reports Volotskova, O., Hawley, T., Stepp, M., Keidar, M. 2012; 2

    View details for DOI 10.1038/srep00636

  • Integrin activation by cold atmospheric plasma New Journal of Physics O. Volotskova, M. A. Stepp, M. Keidar 2012; 14: 053019
  • Arc plasma synthesis of carbon nanostructures: where is the frontier? J. Phys. D: Appl. Phys. M. Keidar, A. Shashurin, Jian Li, Olga Volotskova, M. Kundrapu, T. S. Zhuang 2011; 44: 174006
  • Controlling Diameter Distribution of Catalyst Nanoparticles in Arc Discharge Journal of Nanoscience and Nanotechnology J. Lee, O. Volotskova, A. Shashurin, M. Keidar 2011; 11: 1-6
  • Plasma-Controlled Cell Migration: Localization of Cold Plasma?Cell Interaction Region Plasma Medicine O. Volotskova, A. Shashurin, M. A. Stepp, S. Pal-Ghosh, M. Keidar 2011; 1: 85-89
  • Ignition and temperature behavior of a single-wall carbon nanotube sample Nanotechnology O. Volotskova, A. Shashurin, M. Keidar, Y. Raitses, V. Demidov, S. Adams 2010; 21: 095705
  • The large-scale production of graphene flakes using magnetically-enhanced arc discharge between carbon electrodes Carbon I. Levchenko, O. Volotskova, A. Shashurin, Y. Raitses, K. Ostrikov, M. Keidar 2010; 48: 4556?4577
  • Single-step synthesis and magnetic separation of graphene and carbon nanotubes in arc discharge plasmas Nanoscale (part the web Nobel prize collection on graphene 2010) O. Volotskova, I. Levchenko, A. Shashurin, Y. Raitses, K. Ostrikov, M. Keidar 2010; 2 (10): 2281-2285
  • Mechanism of carbon nanostructure synthesis in arc plasma Physics of Plasmas M. Keidar, A. Shashurin, O. Volotskova, Y. Raitses, I. I. Beilis 2010; 17: 57101
  • Tailored Distribution of Single-Wall Carbon Nanotubes from Arc Plasma Synthesis Using Magnetic Fields ACS Nano O. Volotskova, J. A. Fagan, J. Y. Huh, F. R. Phelan Jr., A. Shashurin, M. Keidar 2010; 4 (9): 5187-5192