Dr. Namjoshi specializes in the care and support of children with intestinal failure on home parenteral nutrition (PN). Her research interests include long term outcomes for patients on home PN, iron in gastrointestinal diseases, renal and bone health in intestinal failure, clinical pathologic correlates in intestinal failure, and the assessment of congenital enteropathies.
- Pediatric Gastroenterology
- Long term outcomes in intestinal failure
- Congenital onset diarrhea and enteropathy (CODEs)
- Nutrition support and intestinal rehabilitation
- Intestinal failure
- Micronutrient transport and absorption
- Intestinal transplant
Clinical Assistant Professor, Pediatrics - Gastroenterology
Medical Director Intestinal Rehabilitation & Nutrition Support, Lucile Packard Children's Hospital (2020 - Present)
Medical Director Children's Home Pharmacy, Lucile Packard Children's Hospital (2020 - Present)
Honors & Awards
Mission Zero award nominee, Lucile Packard Children's Hospital (2020)
High Value Innovation Challenge award winner, Lucile Packard Children's Hospital (2019)
UCLA Children’s Discovery and Innovation Institute Fellow’s Research Support Award, UCLA CDI (2018-2019)
NIH Fellowship Training Grant T32DK07180, NIH (2017-2019)
Housestaff Quality Improvement Award, UCLA (2014)
Resident Research Award, UCLA (2014)
Dean's Merit Scholarship, University of Southern California (2002-2006)
Boards, Advisory Committees, Professional Organizations
Committee Member, NASPGHAN Nutrition Committee (2019 - Present)
Residency: UCLA Pediatric Residency (2014) CA
Board Certification, Pediatric Gastroenterology, Hepatology, & Nutrition, American Board of Pediatrics (2019)
Fellowship: UCLA Pediatric Gastroenterology Fellowship (2019) CA
Board Certification: American Board of Pediatrics, Pediatrics (2014)
Medical Education: Penn State College of Medicine Registrar (2011) PA
Long-Term Dietary Changes in Subjects with Glucose Galactose Malabsorption Secondary to Biallelic Mutations of SLC5A1.
Digestive diseases and sciences
BACKGROUND: Glucose galactose malabsorption (GGM) is a congenital diarrheal disorder of intestinal Na+/glucose cotransport (SGLT1/SLC5A1). The required glucose and galactose-restricted diet has been well described in infancy, but long-term nutrition follow-up is limited.AIM: To perform a comprehensive nutritional assessment on a cohort of patients with GGM to gain insights into the consumption patterns within the population.METHODS: A cross-sectional study examining dietary intake of a GGM cohort using prospective food records. The calories and nutrients of all foods, beverages, and condiments were analyzed with descriptive statistics and compared to intake patterns of age- and sex-matched NHANES groups.RESULTS: The six patients were 0.7-26years old. Whole foods and vegetable fats were major parts of the diet, while dairy and added sweeteners were restricted. Compared to typical US intakes, mean macronutrient distribution was 88th percentile from fat, 18th percentile from carbohydrates, and 78th percentile from protein. Fructose consumption, as a proportion of total sugar intake, decreased with age, from 86.1 to 50.4%. Meanwhile, glucose consumption increased with age, from 13.8 to 48.6% of sugar intake. However, the actual amount of glucose consumed remained low, equivalent to 4th percentile of US consumption level. Galactose intake was marginal throughout life.CONCLUSIONS: A GGM diet is a high-fat and high-protein/low-carbohydrate diet that is rich in fruits and vegetables but limited in dairy and added sugar. Relatively less fructose but more glucose is incorporated into the diet with age. Future studies should investigate the effects of the GGM diet on gut microbiome and long-term health.
View details for DOI 10.1007/s10620-020-06792-4
View details for PubMedID 33433815
SARS-CoV2 Infection in Children with Liver Transplant and Native Liver Disease: An International Observational Registry Study.
Journal of pediatric gastroenterology and nutrition
Increased mortality risk due to severe acute respiratory syndrome coronavirus-2 (SARS-CoV2) infection in adults with native liver disease (LD) and liver transplant (LT) is associated with advanced age and comorbid conditions. We aim to report outcomes for children with LD and LT enrolled in the NASPGHAN/SPLIT SARS-CoV2 registry.In this multicenter observational cohort study, we collected data from 91 patients <21 years (LD 44, LT 47) with laboratory-confirmed SARS-CoV2 infection between April 21 and September 17, 2020.Patients with LD were more likely to require admission (70% vs 43% LT, p = 0.007) and pediatric intensive care unit (PICU) management (32% vs 4% LT, p = 0.001). Seven LD patients required mechanical ventilation (MV) and 2 patients died; no patients in the LT cohort died or required MV. Four LD patients presented in pediatric acute liver failure (PALF), 2 with concurrent multisystem inflammatory syndrome in children (MIS-C); all recovered without LT. Two LD patients had MIS-C alone and one patient died. Bivariable logistic-regression analysis found that patients with non-alcoholic fatty liver disease (NAFLD) (OR 5.6, p = 0.02) and LD (OR 6.1, p = 0.01, vs LT) had higher odds of severe disease (PICU, vasopressor support, MV, renal replacement therapy or death).Although not directly comparable, LT recipients had lower odds of severe SARS-CoV2 infection (vs LD), despite immunosuppression burden. NAFLD patients reported to the registry had higher odds of severe SARS-CoV2 disease. Future controlled studies are needed to evaluate effective treatments and further stratify LD and LT patients with SARS-CoV2 infection.
View details for DOI 10.1097/MPG.0000000000003077
View details for PubMedID 33605666
- Long-Term Dietary Changes in Subjects with Glucose Galactose Malabsorption Secondary to Biallelic Mutations of SLC5A1 Digestive Diseases and Sciences 2021
- Visual Diagnosis: Anal Mass in a 3-year-old Boy. Pediatrics in review 2020; 41 (2): e4–e7
A Novel Case of Carcinoid Tumor in a Pediatric Patient With Short Bowel Syndrome Secondary to Gastroschisis
2020; 1 (2)
View details for DOI 10.1097/PG9.0000000000000023
Anemia of Inflammation in Patients with Intestinal Failure on Home Parenteral Nutrition
SN Compr. Clin. Med.
View details for DOI 10.1007/s42399-020-00404-y
- Development of gastrointestinal function. Pediatric Nutrition edited by Kleinman, R. E., Greer, F. R. American Academy of Pediatrics. 2019; 8th: 17–56
- Nutrition Deficiencies in Children With Intestinal Failure Receiving Chronic Parenteral Nutrition JOURNAL OF PARENTERAL AND ENTERAL NUTRITION 2018; 42 (2): 427–35
- Flu vaccinations among general population inmates in a large urban jail, Los Angeles, 2007-08 Journal of the American Correctional Association 2008: 21-28
- Off-label marketing: a primer for physicians & policy makers. AMSA Online Publication. Reston, VA. 2005