Stav Dor Cullum
Clinical Assistant Professor, Medicine - Oncology
Clinical Focus
- Internal Medicine
Professional Education
-
Board Certification: American Board of Internal Medicine, Internal Medicine (2024)
-
Medical Education: Texas AandM University (2021) TX
-
Residency: Stanford University Internal Medicine Residency CA
All Publications
-
Case report: Dramatic impact of DNA next generation sequencing results using specific targeted therapies-ALK and PIK3CA.
Frontiers in oncology
2024; 14: 1462930
Abstract
In the era of targeted therapies, the clinical importance and utility of next-generation sequencing (NGS) has expanded significantly. Owing to the relative ease and financial feasibility of NGS, the use of personalized treatment strategies has the potential to revolutionize cancer care. In this case report, we explored the use of NGS in salivary gland carcinoma (SGC) and spindle cell neoplasm of the scalp. In our patient with SGC, NGS revealed a GPHN-ALK variant that allowed off-label treatment with alectinib, with a remarkable response in primary and metastatic foci. Similarly, the use of NGS in a cutaneous neoplasm in which no definitive diagnosis could be reached by pathology and which had progressed through standard of care treatment elucidated a PIK3CA mutation in which alpelisib was added and ultimately halted POD. Here, we discuss the use of NGS, future projections, and our recommendations.
View details for DOI 10.3389/fonc.2024.1462930
View details for PubMedID 39659799
View details for PubMedCentralID PMC11628483
-
"Covering provider": an effort to streamline clinical communication chaos.
JAMIA open
2024; 7 (3): ooae057
Abstract
This report describes a root cause analysis of incorrect provider assignments and a standardized workflow developed to improve the clarity and accuracy of provider assignments.A multidisciplinary working group involving housestaff was assembled. Key drivers were identified using value stream mapping and fishbone analysis. A report was developed to allow for the analysis of correct provider assignments. A standardized workflow was created and piloted with a single service line. Pre- and post-pilot surveys were administered to nursing staff and participating housestaff on the unit.Four key drivers were identified. A standardized workflow was created with an exclusive treatment team role in Epic held by a single provider at any given time, with a corresponding patient list column displaying provider information for each patient. Pre- and post-survey responses report decreased confusion, decreased provider identification errors, and increased user satisfaction among RNs and residents with sustained uptake over time.This work demonstrates structured root cause analysis, notably engaging housestaff, to develop a standardized workflow for an understudied and growing problem. The development of tools and strategies to address the widespread burdens resulting from clinical communication failures is needed.
View details for DOI 10.1093/jamiaopen/ooae057
View details for PubMedID 38974405
View details for PubMedCentralID PMC11226879