
Thomas Robert Savage
Clinical Assistant Professor, Medicine
Masters Student in Biomedical Informatics, admitted Autumn 2022
Academic Appointments
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Clinical Assistant Professor, Medicine
All Publications
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Milky Way: Management of Primary Intestinal Lymphangiectasia.
Digestive diseases and sciences
2023
View details for DOI 10.1007/s10620-023-08077-y
View details for PubMedID 37634185
View details for PubMedCentralID 7789053
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Diagnostic Reasoning Prompts Reveal the Potential for Large Language Model Interpretability in Medicine
ARXIV.
https://arxiv.org/abs/2308.06834v1.
2023
Abstract
One of the major barriers to using large language models (LLMs) in medicine is the perception they use uninterpretable methods to make clinical decisions that are inherently different from the cognitive processes of clinicians. In this manuscript we develop novel diagnostic reasoning prompts to study whether LLMs can perform clinical reasoning to accurately form a diagnosis. We find that GPT4 can be prompted to mimic the common clinical reasoning processes of clinicians without sacrificing diagnostic accuracy. This is significant because an LLM that can use clinical reasoning to provide an interpretable rationale offers physicians a means to evaluate whether LLMs can be trusted for patient care. Novel prompting methods have the potential to expose the black box of LLMs, bringing them one step closer to safe and effective use in medicine.
https://arxiv.org/abs/2308.06834v1 -
Milky Way: Management of Primary Intestinal Lymphangiectasia
Digestive Diseases and Sciences
2023
View details for DOI 10.1007/s10620-023-08077-y
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Availability and content of clinical guidance for tobacco use and dependence treatment-United States, 2000-2019
PREVENTIVE MEDICINE
2022; 164: 107276
Abstract
Evidence-based treatments for tobacco use and dependence can increase cessation success but remain underutilized. Health professional societies and voluntary health organizations (advising organizations) are uniquely positioned to influence the delivery of cessation treatments by providing clinical guidance for healthcare providers. This study aimed to review the guidance produced by these organizations for content and consistency with current evidence. Documents discussing healthcare providers' role in treatment of tobacco use and dependence produced by US-based advising organizations between 2000 and 2019 were identified in both peer-reviewed and grey (i.e., informally or non-commercially published) literature. Extraction of variables, defined in terms of healthcare provider role and endorsement of specific treatment(s), was completed by two independent reviewers. Review of 38 identified documents sponsored by 57 unique advising organizations revealed deficits in the direction of comprehensive care and incorporation of the most recent evidence for treatment of tobacco use and dependence. Documents endorsed: screening (74%), pharmacotherapy (68%), counseling (89%), or follow-up (37%). Few documents endorsed more recent evidence-based treatments including combination nicotine replacement therapy (18%), and text- (11%) and web-based (11%) interventions. Advising organizations have opportunities to address identified gaps and enhance clinical guidance to contribute toward expanding the provision of comprehensive tobacco cessation support.
View details for DOI 10.1016/j.ypmed.2022.107276
View details for Web of Science ID 000878634600019
View details for PubMedID 36152817
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Artificial Intelligence in Medical Education
ACADEMIC MEDICINE
2021; 96 (9): 1229-1230
View details for Web of Science ID 000688214700011
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Enhancing patient engagement during virtual care: A conceptual model and rapid implementation at an academic medical center
NEJM: Catalyst Innovations in Care
2020
View details for DOI 10.1056/CAT.20.0262