Bio


Stanford University School of Medicine M.D. '25
University of Cambridge MPhil in Epidemiology '21, using advanced biostatistics to enhance predictive validity of cardiovascular disease biomarkers.
Harvard College A.B. with Honors in Human Evolutionary Biology, Minor in Chemistry '20

Education & Certifications


  • MPhil, University of Cambridge, Epidemiology (2021)
  • A.B., Harvard College, Human Evolutionary Biology, Minor in Chemistry (2020)

Lab Affiliations


All Publications


  • Forty Years Since the Epidemic: Modern Paradigms in HIV Diagnosis and Treatment. Cureus Patel, K., Zhang, A., Zhang, M. H., Bunachita, S., Baccouche, B. M., Hundal, H., Lavado, L. K., Agarwal, A., Malik, P., Patel, U. K. 2021; 13 (5): e14805

    Abstract

    Human immunodeficiency virus (HIV) is a viral infection that, when transmitted through the exchange of certain bodily fluids, destroys various immune cells and contributes to an overall weakened immune system. If left untreated, HIV progresses to acquired immunodeficiency syndrome (AIDS) - a chronic, life-threatening condition that puts patients at risk for opportunistic infections. Since the emergence of HIV nearly a century ago, the world has seen tremendous advances in elucidating its pathology and progression. These advances have been accompanied by an increased understanding of how subsequent effects and symptoms manifest in afflicted individuals. These discoveries, coupled with the ever-improving technologies and methodologies used for detection and treatment, provide the scientific and medical community with a solid grasp of HIV. Despite this significant headway, there is still much progress to be made; medical advances have allowed people with HIV to manage their disease and live a longer, healthier life, but a definite cure is yet to be found. Thus, the following literature review serves as both an extensive compendium of our current understanding of HIV - its pathology, testing/detection, repercussions, and treatment - and an acknowledgement of the areas that still require further research.

    View details for DOI 10.7759/cureus.14805

    View details for PubMedID 34094761

    View details for PubMedCentralID PMC8172004

  • Did giraffe cardiovascular evolution solve the problem of heart failure with preserved ejection fraction? EVOLUTION MEDICINE AND PUBLIC HEALTH Natterson-Horowitz, B., Baccouche, B. M., Mary, J., Shivkumar, T., Bertelsen, M., Aalkjaer, C., Smerup, M. H., Ajijola, O. A., Hadaya, J., Wang, T. 2021; 9 (1): 248-255
  • Complete and Partial Aortic Occlusion for the Treatment of Hemorrhagic Shock in Swine. Journal of visualized experiments : JoVE Williams, A. M., Bhatti, U. F., Dennahy, I. S., Chtraklin, K., Chang, P., Graham, N. J., Baccouche, B. M., Roy, S., Harajli, M., Zhou, J., Nikolian, V. C., Deng, Q., Tian, Y., Liu, B., Li, Y., Hays, G. L., Hays, J. L., Alam, H. B. 2018

    Abstract

    Hemorrhage remains the leading cause of preventable deaths in trauma. Endovascular management of non-compressible torso hemorrhage has been at the forefront of trauma care in recent years. Since complete aortic occlusion presents serious concerns, the concept of partial aortic occlusion has gained a growing attention. Here, we present a large animal model of hemorrhagic shock to investigate the effects of a novel partial aortic balloon occlusion catheter and compare it with a catheter that works on the principles of complete aortic occlusion. Swine are anesthetized and instrumented in order to conduct controlled fixed-volume hemorrhage, and hemodynamic and physiological parameters are monitored. Following hemorrhage, aortic balloon occlusion catheters are inserted and inflated in the supraceliac aorta for 60 min, during which the animals receive whole-blood resuscitation as 20% of the total blood volume (TBV). Following balloon deflation, the animals are monitored in a critical care setting for 4 h, during which they receive fluid resuscitation and vasopressors as needed. The partial aortic balloon occlusion demonstrated improved distal mean arterial pressures (MAPs) during the balloon inflation, decreased markers of ischemia, and decreased fluid resuscitation and vasopressor use. As swine physiology and homeostatic responses following hemorrhage have been well-documented and are like those in humans, a swine hemorrhagic shock model can be used to test various treatment strategies. In addition to treating hemorrhage, aortic balloon occlusion catheters have become popular for their role in cardiac arrest, cardiac and vascular surgery, and other high-risk elective surgical procedures.

    View details for DOI 10.3791/58284

    View details for PubMedID 30199035

    View details for PubMedCentralID PMC6231876