Bio-X
Showing 341-360 of 1,075 Results
-
Aaron D. Gitler
Stanford Medicine Basic Science Professor
Current Research and Scholarly InterestsWe investigate the mechanisms of human neurodegenerative diseases, including Alzheimer disease, Parkinson disease, and ALS. We don't limit ourselves to one model system or experimental approach. We start with yeast, perform genetic and chemical screens, and then move to other model systems (e.g. mammalian tissue culture, mouse, fly) and even work with human patient samples (tissue sections, patient-derived cells, including iPS cells) and next generation sequencing approaches.
-
Linda Giudice
Stanley McCormick Memorial Professor in the School of Medicine, Emerita
Current Research and Scholarly InterestsOur research is in reproductive endocrinology and reproductive genomics. It focuses on human endometrial biology as it relates to basic biological mechanisms underlying steroid hormone action in this tissue, normal and abnormal placenta-decidua interactions, mechanisms underlying placentation and abnormal fetal growth, endometrial stem cells, and functional genomics for diagnostics and therapeutics of endometrial disorders. We also study mechanisms underlying ovarian follicle steroidogenesis.
-
Jeffrey S. Glenn, M.D., Ph.D.
Joseph D. Grant Professor and Professor of Microbiology and Immunology
Current Research and Scholarly InterestsDr. Glenn's primary interest is in molecular virology, with a strong emphasis on translating this knowledge into novel antiviral therapies. Other interests include exploitation of hepatic stem cells, engineered human liver tissues, liver cancer, and new biodefense antiviral strategies.
-
Gary Glover
Professor of Radiology (Radiological Sciences Lab) and, by courtesy, of Psychology and of Electrical Engineering
Current Research and Scholarly InterestsMy present research is devoted to the advancement of functional magnetic resonance imaging sciences for applications in basic understanding of the brain in health and disease. We collaborate closely with departmental clinicians and with others in the school of medicine, humanities, and the engineering sciences.
-
Anna L Gloyn
Professor of Pediatrics (Endocrinology) and of Genetics
Current Research and Scholarly InterestsAnna's current research projects are focused on the translation of genetic association signals for type 2 diabetes and glycaemic traits into cellular and molecular mechanisms for beta-cell dysfunction and diabetes. Her group uses a variety of complementary approaches, including human genetics, functional genomics, physiology and islet-biology to dissect out the molecular mechanisms driving disease pathogenesis.
-
Ashish Goel
Professor of Management Science and Engineering and, by courtesy, of Computer Science
BioAshish Goel is a Professor of Management Science and Engineering and (by courtesy) Computer Science at Stanford University. He received his PhD in Computer Science from Stanford in 1999, and was an Assistant Professor of Computer Science at the University of Southern California from 1999 to 2002. His research interests lie in the design, analysis, and applications of algorithms.
-
Lauren Goins
Assistant Professor of Developmental Biology
Current Research and Scholarly InterestsThe Goins lab aims to understand how cells make decisions. Our research focuses on how young, immature blood stem cells, with the potential to become many different cell types, choose between these cell fates.
-
Garry Gold
Stanford Medicine Professor of Radiology and Biomedical Imaging
Current Research and Scholarly InterestsMy primary focus is application of new MR imaging technology to musculoskeletal problems. Current projects include: Rapid MRI for Osteoarthritis, Weight-bearing cartilage imaging with MRI, and MRI-based models of muscle. We are studying the application of new MR imaging techniques such as rapid imaging, real-time imaging, and short echo time imaging to learn more about biomechanics and pathology of bones and joints. I am also interested in functional imaging approaches using PET-MRI.
-
Jeffrey Goldberg, MD, PhD
Blumenkranz Smead Professor
Current Research and Scholarly InterestsLab research on molecular mechanisms of survival and regeneration in the visual system; retinal development and stem cell biology; nanoparticles and tissue engineering. Clinical trials in imaging, biomarker development, and neuroprotection and vision restoration in glaucoma and other neurodegenerative diseases.
-
Mary Kane Goldstein
Professor of Health Policy, Emerita
Current Research and Scholarly InterestsHealth services research in primary care and geriatrics: developing, implementing, and evaluating methods for clinical quality improvement. Current work includes applying health information technology to quality improvement through clinical decision support (CDS) integrated with electronic health records; encoding clinical knowledge into computable formats in automated knowledge bases; natural language processing of free text in electronic health records; analyzing multiple comorbidities
-
Andrea Goldstein-Piekarski
Assistant Professor (Research) of Psychiatry and Behavioral Sciences (Sleep Medicine)
BioDr. Goldstein-Piekarski directs the Computational Psychiatry, Neuroscience, and Sleep Laboratory (CoPsyN Sleep Lab) as an Assistant Professor in the Department of Psychiatry and Behavioral Sciences at Stanford University School of Medicine and PI within the Sierra-Pacific Mental Illness Research, Education and Clinical Center (MIRECC) at the Palo Alto VA. She received her PhD in 2014 at the University of California, Berkeley where she studied the consequences of sleep on emotional brain function. She then completed a Postdoctoral fellowship at Stanford focusing on understanding the brain basis of anxiety and depression.
As the director of the CoPsyN Sleep Lab she is developing a translational, interdisciplinary research program that combines human neuroimaging, high-density EEG sleep recording, and computational modeling to understand the neural mechanisms through which sleep disruption contributes to affective disorders, particularly depression, across the lifespan. The ultimate goals of this research are to (1) develop mechanistically-informed interventions that directly target aspects of sleep and brain function to prevent and treat affective disorders and (2) identify novel biomarkers which can identify which individuals are most likely to experience improved mood following targeted sleep interventions.
This work is currently supported by The KLS Foundation, a R01 from National Institute of Mental Health, and a R61 from the National Institute of Mental Health. -
Natalia Gomez-Ospina
Assistant Professor of Pediatrics (Genetics)
Current Research and Scholarly InterestsDr. Gomez-Ospina is a physician scientist and medical geneticist with a strong interest in the diagnosis and management of genetic diseases.
1) Lysosomal storage diseases:
Her research program is on developing better therapies for a large class of neurodegenerative diseases in children known as lysosomal storage disorders. Her current focus is on developing genome editing of hematopoietic stem cells as a therapeutic approach for these diseases beginning with Mucopolysaccharidosis type 1 and Gaucher disease. She established a genetic approach where therapeutic proteins can be targeted to a single well-characterized place in the genome known as a safe harbor. This approach constitutes a flexible, “one size fits all” approach that is independent of specific genes and mutations. This strategy, in which the hematopoietic system is commandeered to express and deliver therapeutic proteins to the brain can potentially change the current approaches to treating childhood neurodegenerative diseases and pave the way for alternative therapies for adult neurodegenerative disorders such as Alzheimer’s and Parkinson’s disease
2) Point of care ammonia testing
She also works in collaboration with other researchers at Stanford to develop point-of-care testing for serum ammonia levels. Such device will greatly improve the quality of life of children and families with metabolic disorders with hyperammonemia.
3) Gene discovery
Dr Gomez-Ospina lead a multi-institutional collaboration resulting in the discovery of a novel genetic cause of neonatal and infantile cholestatic liver disease. She collaborated in the description of two novel neurologic syndromes caused by mutations in DYRK1 and CHD4.
For more information go to our website:
https://www.gomezospina.com/ -
Benjamin Good
Assistant Professor of Applied Physics
BioBenjamin Good is a theoretical biophysicist with a background in experimental evolution and population genetics. He is interested in the short-term evolutionary dynamics that emerge in rapidly evolving microbial populations like the gut microbiome. Technological advances are revolutionizing our ability to peer into these evolving ecosystems, providing us with an increasingly detailed catalog of their component species, genes, and pathways. Yet a vast gap still remains in understanding the population-level processes that control their emergent structure and function. Our group uses tools from statistical physics, population genetics, and computational biology to understand how microscopic growth processes and genome dynamics at the single cell level give rise to the collective behaviors that can be observed at the population level. Projects range from basic theoretical investigations of non-equilibrium processes in microbial evolution and ecology, to the development of new computational tools for measuring these processes in situ in both natural and experimental microbial communities. Through these specific examples, we seek to uncover unifying theoretical principles that could help us understand, forecast, and eventually control the ecological and evolutionary dynamics that take place in these diverse scenarios.
-
Zinaida Good, Ph.D.
Assistant Professor of Medicine (Immunology and Rheumatology)
Current Research and Scholarly InterestsOur laboratory integrates cutting-edge synthetic biology, immunology, and machine learning to engineer T cell therapies for cancer and autoimmune diseases. We have 3 research areas:
- Analysis of clinical single-cell and spatial transcriptomics datasets from T cell therapy trials to identify mechanisms of resistance
- Building AI systems to generate T cell designs predicted to improve patient outcomes
- Genetic screens of novel T cell designs in models that mimic key mechanisms of resistance -
Miriam B. Goodman
Mrs. George A. Winzer Professor of Cell Biology
Current Research and Scholarly InterestsWe study the molecular events that give rise to the sensation of touch and chemical stressors that compromise touch sensation in C. elegans. To do this, we use a combination of quantitative behavioral analysis, genetics, in vivo electrophysiology, and heterologous expression of ion channels. We collaborate with physicists and other physiologist to expand our experimental research.
-
Stuart Goodman, MD, PhD
The Robert L. and Mary Ellenburg Professor of Surgery and Professor, by courtesy, of Bioengineering
On Partial Leave from 09/01/2024 To 08/31/2025Current Research and Scholarly InterestsAs an academic orthopaedic surgeon, my interests center on adult reconstructive surgery, arthritis surgery, joint replacement, biomaterials, biocompatibility, tissue engineering, mesenchymal stem cells. Collaborative clinical, applied and basic research studies are ongoing.
-
Kenneth Goodson
Senior Associate Dean for Research and Faculty Affairs, Davies Family Provostial Professor, and Professor, by courtesy, of Materials Science and Engineering
Current Research and Scholarly InterestsProf. Goodson’s Nanoheat Lab studies heat transfer in electronic nanostructures, microfluidic heat sinks, and packaging, focussing on basic transport physics and practical impact for industry. We work closely with companies on novel cooling and packaging strategies for power devices, portables, ASICs, & data centers. At present, sponsors and collaborators include ARPA-E, the NSF POETS Center, SRC ASCENT, Google, Intel, Toyota, Ford, among others.
-
William Rowland Goodyer, MD/PhD
Assistant Professor of Pediatrics (Cardiology)
BioDr. Goodyer is a physician scientist who specializes in Pediatric Cardiology and Electrophysiology. Will graduated from McGill University (Montreal, Canada) with a BSc in Biology prior to completing his graduate studies at Stanford University in the Medical Scientist Training Program (MSTP). He subsequently completed residency training in Pediatrics at Boston Children’s Hospital before returning to Stanford to complete a fellowship in Pediatric Cardiology and advanced fellowship in Pediatric Electrophysiology. He additionally performed a postdoctoral fellowship in the Sean Wu laboratory at the Stanford Cardiovascular Institute where he developed the first comprehensive single-cell gene atlas of the entire murine cardiac conduction system (CCS) as well as pioneered the generation of optical imaging agents for the real-time visualization of the CCS to help prevent accidental surgical damage during heart surgeries. Will's lab (www.goodyerlab.com) focuses on basic science advances aimed at the improved diagnosis and treatment of cardiac arrhythmias.
-
Deborah M Gordon
Paul S. and Billie Achilles Professor of Environmental Biology
Current Research and Scholarly InterestsProfessor Deborah M Gordon studies the evolutionary ecology of collective behavior. Ant colonies operate without central control, using local interactions to regulate colony behavior.
