Bio-X
Showing 961-980 of 1,052 Results
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Benjamin Van Roy
Professor of Electrical Engineering, of Management Science and Engineering and, by courtesy, of Computer Science
BioBenjamin Van Roy is a Professor at Stanford University, where he has served on the faculty since 1998. His current research focuses on reinforcement learning. Beyond academia, he leads a DeepMind Research team in Mountain View, and has also led research programs at Unica (acquired by IBM), Enuvis (acquired by SiRF), and Morgan Stanley.
He is a Fellow of INFORMS and IEEE and has served on the editorial boards of Machine Learning, Mathematics of Operations Research, for which he co-edited the Learning Theory Area, Operations Research, for which he edited the Financial Engineering Area, and the INFORMS Journal on Optimization. He received the SB in Computer Science and Engineering and the SM and PhD in Electrical Engineering and Computer Science, all from MIT, where his doctoral research was advised by John N. Tstitsiklis. He has been a recipient of the MIT George C. Newton Undergraduate Laboratory Project Award, the MIT Morris J. Levin Memorial Master's Thesis Award, the MIT George M. Sprowls Doctoral Dissertation Award, the National Science Foundation CAREER Award, the Stanford Tau Beta Pi Award for Excellence in Undergraduate Teaching, the Management Science and Engineering Department's Graduate Teaching Award, and the Lanchester Prize. He was the plenary speaker at the 2019 Allerton Conference on Communications, Control, and Computing. He has held visiting positions as the Wolfgang and Helga Gaul Visiting Professor at the University of Karlsruhe, the Chin Sophonpanich Foundation Professor and the InTouch Professor at Chulalongkorn University, a Visiting Professor at the National University of Singapore, and a Visiting Professor at the Chinese University of Hong Kong, Shenzhen. -
Shreyas Vasanawala, MD/PhD
William R. Brody Professor of Pediatric Radiology and Child Health
Current Research and Scholarly InterestsOur group is focused on developing new fast and quantitative MRI techniques.
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Anand Veeravagu, MD, FAANS, FACS
Associate Professor of Neurosurgery and, by courtesy, of Orthopaedic Surgery
Current Research and Scholarly InterestsThe focus of my laboratory is to utilize precision medicine techniques to improve the diagnosis and treatment of neurologic conditions. From traumatic brain injury to spinal scoliosis, the ability to capture detailed data regarding clinical symptoms and treatment outcomes has empowered us to do better for patients. Utilize data to do better for patients, that’s what we do.
Stanford Neurosurgical Ai and Machine Learning Lab
http://med.stanford.edu/neurosurgery/research/AILab.html -
Alexander Michael Vezeridis, MD, PhD
Assistant Professor of Radiology (Interventional Radiology)
BioAlexander Vezeridis MD, PhD is an Assistant Professor of Radiology at Stanford University School of Medicine, and a physician-scientist specializing in Interventional Radiology. His clinical expertise includes interventional oncology, biliary disease and endoscopy, venous disease, portal hypertension, urologic interventions, women’s and men’s health interventions, and general vascular/interventional radiology.
Dr. Vezeridis is an active researcher with expertise in translational techniques in engineering to make image-guided interventions safer and more effective for patients.
Dr. Vezeridis obtained his undergraduate, MD, and PhD degrees from Boston University. He completed a two year post-doctoral training at UC San Diego in ultrasound molecular imaging under the auspices of the Cancer Researchers in Nanotechnology (CRIN) R25T, followed by residency and fellowship at UC San Diego.
Dr. Vezeridis is highly committed to training the next generation, including students, residents, fellows, and engineering graduate students through co-directing Bio301B.
Dr. Vezeridis has a strong interest in medical device development and commercialization, and completed the Stanford Biodesign Faculty Fellowship. -
José Vilches-Moure, DVM, PhD
Associate Professor of Comparative Medicine
BioDr. José G. Vilches-Moure, DVM, PhD, Associate Professor, received his DVM degree from Purdue University in Indiana in 2007. He completed his residency training in Anatomic Pathology (with emphasis in pathology of laboratory animal species) and his PhD in Comparative Pathology at the University of California-Davis. He joined Stanford in 2015, is the founder and current Faculty Director for Comparative and Experimental Pathology Post-doctoral Fellowship, the current Faculty Director of the Master of Laboratory Animal Science (MLAS) Graduate Program, and is the past Director of the Animal Histology Services (AHS; 2015-2022). Dr. Vilches-Moure is a diplomate of the American College of Veterinary Pathologists, and his collaborative research interests include refinement of animal models, cancer biology and early cancer detection techniques, cardiac development and pathology, developmental pathology, and host-pathogen interactions. His teaching interests include comparative anatomy/histology, general pathology, comparative pathology, and pathology of laboratory animal species.
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Anne Villeneuve
Berthold and Belle N. Guggenhime Professor and Professor of Developmental Biology and of Genetics
Current Research and Scholarly InterestsMechanisms underlying homologous chromosome pairing, DNA recombination and chromosome remodeling during meiosis, using the nematode Caenorhabditis elegans as an experimental system. High-resolution 3-D imaging of dynamic reorganization of chromosome architecture. Role of protease inhibitors in regulating sperm activation.
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Hannes Vogel MD
Professor of Pathology and of Pediatrics (Pediatric Genetics) and, by courtesy, of Neurosurgery, Neurology and Neurological Sciences and of Comparative Medicine
Current Research and Scholarly InterestsMy research interests include nerve and muscle pathology, mitochondrial diseases, pediatric neurooncology, and transgenic mouse pathology.
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Douglas Vollrath
Professor of Genetics and, by courtesy, of Ophthalmology
Current Research and Scholarly InterestsThe Vollrath lab works to uncover molecular mechanisms relevant to the health and pathology of the outer retina. We study metabolic and other cellular interactions between the glial-like retinal pigment epithelium (RPE) and adjacent photoreceptors, with the goals of understanding the pathogenesis of photoreceptor degenerative diseases such as age-related macular degeneration and retinitis pigmentosa, and developing therapies.
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Ayelet Voskoboynik
Assistant Professor (Research) of Biology
Current Research and Scholarly InterestsWe study the mechanisms by which animals differentiate between self and non-self, and how stem cells and immune cells coordinate to form tissues during development, regeneration, transplantation, and aging. By leveraging the natural stem cell-mediated development, regeneration, and chimerism in the colonial chordate Botryllus schlosseri, we investigate stem cell competition and the decline in regenerative capacity during aging.
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Jelena Vuckovic
Jensen Huang Professor of Global Leadership, Professor of Electrical Engineering and, by courtesy, of Applied Physics
Current Research and Scholarly InterestsJelena Vuckovic’s research interests are broadly in the areas of nanophotonics, quantum and nonlinear optics. Her lab develops semiconductor-based photonic chip-scale systems with goals to probe new regimes of light-matter interaction, as well as to enable platforms for future classical and quantum information processing technologies. She also works on transforming conventional photonics with the concept of inverse design, where optimal photonic devices are designed from scratch using computer algorithms with little to no human input. Her current projects include quantum and nonlinear optics, cavity QED, and quantum information processing with color centers in diamond and in silicon carbide, heterogeneously integrated chip-scale photonic systems, and on-chip laser driven particle accelerators.
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Anthony Wagner
Lucie Stern Professor in the Social Sciences
Current Research and Scholarly InterestsCognitive neuroscience of memory and cognitive/executive control in young and older adults. Research interests include encoding and retrieval mechanisms; interactions between declarative, nondeclarative, and working memory; forms of cognitive control; neurocognitive aging; functional organization of prefrontal cortex, parietal cortex, and the medial temporal lobe; assessed by functional MRI, scalp and intracranial EEG, and transcranial magnetic stimulation.
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Soichi Wakatsuki
Professor of Photon Science and of Structural Biology
Current Research and Scholarly InterestsUbiquitin signaling: structure, function, and therapeutics
Ubiquitin is a small protein modifier that is ubiquitously produced in the cells and takes part in the regulation of a wide range of cellular activities such as gene transcription and protein turnover. The key to the diversity of the ubiquitin roles in cells is that it is capable of interacting with other cellular proteins either as a single molecule or as different types of chains. Ubiquitin chains are produced through polymerization of ubiquitin molecules via any of their seven internal lysine residues or the N-terminal methionine residue. Covalent interaction of ubiquitin with other proteins is known as ubiquitination which is carried out through an enzymatic cascade composed of the ubiquitin-activating (E1), ubiquitin-conjugating (E2), and ubiquitin ligase (E3) enzymes. The ubiquitin signals are decoded by the ubiquitin-binding domains (UBDs). These domains often specifically recognize and non-covalently bind to the different ubiquitin species, resulting in distinct signaling outcomes.
We apply a combination of the structural (including protein crystallography, small angle x-ray scattering, cryo-electron microscopy (Cryo-EM) etc.), biocomputational and biochemical techniques to study the ubiquitylation and deubiquitination processes, and recognition of the ubiquitin chains by the proteins harboring ubiquitin-binding domains. Current research interests including SARS-COV2 proteases and their interactions with polyubiquitin chains and ubiquitin pathways in host cell responses, with an ultimate goal of providing strategies for effective therapeutics with reduced levels of side effects.
Protein self-assembly processes and applications.
The Surface layers (S-layers) are crystalline protein coats surrounding microbial cells. S-layer proteins (SLPs) regulate their extracellular, self-assembly by crystallizing when exposed to an environmental trigger. We have demonstrated that the Caulobacter crescentus SLP readily crystallizes into sheets both in vivo and in vitro via a calcium-triggered multistep assembly pathway. Observing crystallization using a time course of Cryo-EM imaging has revealed a crystalline intermediate wherein N-terminal nucleation domains exhibit motional dynamics with respect to rigid lattice-forming crystallization domains. Rate enhancement of protein crystallization by a discrete nucleation domain may enable engineering of kinetically controllable self-assembling 2D macromolecular nanomaterials. In particular, this is inspiring designing robust novel platform for nano-scale protein scaffolds for structure-based drug design and nano-bioreactor design for the carbon-cycling enzyme pathway enzymes. Current research focuses on development of nano-scaffolds for high throughput in vitro assays and structure determination of small and flexible proteins and their interaction partners using Cryo-EM, and applying them to cancer and anti-viral therapeutics.
Multiscale imaging and technology developments.
Multimodal, multiscale imaging modalities will be developed and integrated to understand how molecular level events of key enzymes and protein network are connected to cellular and multi-cellular functions through intra-cellular organization and interactions of the key machineries in the cell. Larger scale organization of these proteins will be studied by solution X-ray scattering and Cryo-EM. Their spatio-temporal arrangements in the cell organelles, membranes, and cytosol will be further studied by X-ray fluorescence imaging and correlated with cryoEM and super-resolution optical microscopy. We apply these multiscale integrative imaging approaches to biomedical, and environmental and bioenergy research questions with Stanford, DOE national labs, and other domestic and international collaborators. -
Virginia Walbot
Professor of Biology, Emerita
Current Research and Scholarly InterestsOur current focus is on maize anther development to understand how cell fate is specified. We discovered that hypoxia triggers specification of the archesporial (pre-meiotic) cells, and that these cells secrete a small protein MAC1 that patterns the adjacent soma to differentiate as endothecial and secondary parietal cell types. We also discovered a novel class of small RNA: 21-nt and 24-nt phasiRNAs that are exceptionally abundant in anthers and exhibit strict spatiotemporal dynamics.
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Ken Waldron
Professor (Research) of Mechanical Engineering, Emeritus
BioKenneth J. Waldron is Professor of Mechanical and Mechatronic Engineering at UTS. He is also Professor Emeritus from the Design Group in the Department of Mechanical Engineering of Stanford University. He holds bachelors and masters degrees from the University of Sydney, and PhD from Stanford. He works in machine design, and design methodology with a particular focus on robotic and mechatronic systems.
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Dennis Wall
Professor of Pediatrics (Clinical Informatics), of Biomedical Data Science and, by courtesy, of Psychiatry and Behavioral Sciences
Current Research and Scholarly InterestsSystems biology for design of clinical solutions that detect and treat disease
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Guenther Walther
Professor of Statistics
BioGuenther Walther studied mathematics, economics, and computer science at the University of Karlsruhe in Germany and received his Ph.D. in Statistics from UC Berkeley in 1994.
His research has focused on statistical methodology for detection problems, shape-restricted inference, and mixture analysis, and on statistical problems in astrophysics and in flow cytometry.
He received a Terman fellowship, a NSF CAREER award, and the Distinguished Teaching Award of the Dean of Humanities and Sciences at Stanford. He has served on the editorial boards of the Journal of Computational and Graphical Statistics, the Journal of the Royal Statistical Society, the Annals of Statistics, the Annals of Applied Statistics, and Statistical Science. He was program co-chair of the 2006 Annual Meeting of the Institute of Mathematical Statistics and served on the executive committee of IMS from 1998 to 2012. -
Brian A. Wandell
Isaac and Madeline Stein Family Professor and Professor, by courtesy, of Electrical Engineering, of Ophthalmology and of Education
Current Research and Scholarly InterestsModels and measures of the human visual system. The brain pathways essential for reading development. Diffusion tensor imaging, functional magnetic resonance imaging and computational modeling of visual perception and brain processes. Image systems simulations of optics and sensors and image processing. Data and computation management for reproducible research.
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Tom Wandless
Professor of Chemical and Systems Biology
Current Research and Scholarly InterestsWe employ an interdisciplinary approach to studies of biological systems, combining synthetic chemistry with biochemistry, cell biology, and structural biology. We invent tools for biology and we are motivated by approaches that enable new experiments with unprecedented control. These new techniques may also provide a window into mechanisms involved in maintaining cellular homeostasis. Protein quality control is a particular interest at present.
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Adam Wang
Assistant Professor of Radiology and, by courtesy, of Electrical Engineering
BioMy research group develops technologies for advanced x-ray and CT imaging, including artificial intelligence for CT acquisition, reconstruction, and image processing; spectral imaging, including photon counting CT (PCCT) and dual-layer flat-panel detectors; novel system and detector designs; and their applications in diagnostic imaging and image-guided procedures. I am also the Director of the Photon Counting CT Lab, Zeego Lab, and Tabletop X-Ray Lab.
I completed my PhD in Electrical Engineering at Stanford, developing strategies for maximizing the information content of dual energy CT and photon counting detectors. I then pursued a postdoctoral fellowship at Johns Hopkins in the I-STAR Lab, developing reconstruction and registration methods for x-ray based image-guided surgery. I was then a Senior Scientist at Varian Medical Systems, developing x-ray/CT methods for image-guided radiation therapy, before returning to Stanford in 2018, where I now lead a comprehensive research program in advanced x-ray and CT imaging systems and methods, with funding from NIH, DOD, DOE, and industry partners. -
Bo Wang
Assistant Professor of Bioengineering and, by courtesy, Developmental Biology
Current Research and Scholarly InterestsResearch interests:
(1) Systems biology of whole-body regeneration
(2) Cell type evolution through the lens of single-cell multiomic sequencing analysis
(3) Quantitative biology of brain regeneration
(4) Regeneration of animal-algal photosymbiotic systems