Wu Tsai Neurosciences Institute


Showing 1-22 of 22 Results

  • Cholawat Pacharinsak, DVM, PhD

    Cholawat Pacharinsak, DVM, PhD

    Assistant Professor of Comparative Medicine at the Stanford University Medical Center

    BioCholawat Pacharinsak, DVM, PhD Assistant Professor and Director of Anesthesia, Pain Management, at Stanford University’s Department of Comparative Medicine; he is a Diplomate of the American College of Veterinary Anesthesia and Analgesia (DACVAA). He received his DVM from Chulalongkorn University, Thailand and trained in an Anesthesiology/Pain Management residency program and received his Master's degree at Washington State University. He completed his PhD in Comparative and Molecular Biosciences from the University of Minnesota. Prior to arriving at Stanford, Dr. Pacharinsak was a faculty member in Anesthesiology and Pain Management at Michigan State University and Purdue University; and served as a Clinical Specialist at UCLA’s David Geffen School of Medicine. His research focuses on understanding the neurobiology of cancer pain, chemotherapeutic-induced peripheral neuropathy, acute surgical pain models, and methods to improve clinical pain management e.g. sustained release analgesics supporting refinement. Research methodology includes electrophysiologic and behavioral techniques.

  • Daniel Palanker, PhD

    Daniel Palanker, PhD

    Director of HEPL, Professor of Ophthalmology and, by courtesy, of Electrical Engineering

    Current Research and Scholarly InterestsInteractions of electric field and light with biological cells and tissues and their applications to imaging, diagnostics, therapeutics and prosthetics, primarily in ophthalmology.
    Specific fields of interest:
    Electronic retinal prosthesis;
    Electronic enhancement of tear secretion;
    Electronic control of blood vessels;
    Non-damaging retinal laser therapy;
    Ultrafast laser surgery;
    Interferometric imaging of neural signals;
    Cell transplantation and retinal plasticity.

  • Theo Palmer

    Theo Palmer

    Professor of Neurosurgery

    Current Research and Scholarly InterestsMembers of the Palmer Lab study the biology of neural stem cells in brain development and in the adult. Our primary goal is to understand how genes and environment synergize in influencing stem cell behavior during development and how mild genetic or environmental risk factors for disease may synergize in their detrimental effects on brain development or in the risk of neuronal loss in age-related degenerative disease.

  • Karen J. Parker, PhD

    Karen J. Parker, PhD

    Associate Professor (Research) of Psychiatry and Behavioral Sciences (Major Laboratories and Clinical Translational Neurosciences Incubator)

    Current Research and Scholarly InterestsThe Parker Lab conducts research on the biology of social functioning in monkeys, typically developing humans, and patients with social impairments.

  • Josef Parvizi, MD, PhD

    Josef Parvizi, MD, PhD

    Professor of Neurology at the Stanford University Medical Center

    BioDr Parvizi completed his medical internship at Mayo Clinic and Neurology Residency at BIDMC Harvard Medical School before joining the UCLA for fellowship training in clinical neurophysiology and epilepsy. He has worked at Stanford University Medical Center since 2007 and specializes in treating patients with uncontrollable seizures. Dr. Parvizi is the principal investigator in the Laboratory of Behavioral and Cognitive Neuroscience whose research activities have been supported by National Institute of Health, National Science Foundation, and private foundations. To find out more about Dr Parvizi's scholarly activities please visit http://med.stanford.edu/parvizi-lab.html.

  • Anca M. Pasca, MD

    Anca M. Pasca, MD

    Assistant Professor of Pediatrics at the Lucile Salter Packard Children's Hospital

    Current Research and Scholarly InterestsThe research focus of the lab is to understand molecular mechanisms underlying neurodevelopmental disorders associated with premature birth, neonatal and fetal brain injury with the long-term goal of translating the lab’s findings into therapeutics. The research team employs a multidisciplinary approach involving genetics, molecular and developmental neurobiology, animal models and neural cells differentiated from patient-derived induced pluripotent stem (iPS) cells. In particular, the lab is using a powerful 3D human brain-region specific organoid system developed at Stanford (Nature Methods, 2015; Nature Protocols, 2018) to ask questions about brain injury during development.

    https://www.neopascalab.org/

  • Sergiu P. Pasca

    Sergiu P. Pasca

    Assistant Professor of Psychiatry and Behavioral Sciences (Sleep Disorder/Sleep Center)

    Current Research and Scholarly InterestsA critical challenge in understanding the intricate programs underlying development, assembly and dysfunction of the human brain is the lack of direct access to intact, functioning human brain tissue for detailed investigation by imaging, recording, and stimulation.
    Our lab is using pluripotent stem cells derived non-invasively from human individuals to generate in a dish specific regions of the human brain in a functional 3D preparation we have developed. We are using months-to-years long ‘brain-a-dish’ cultures (also known as brain region-specific organoids or spheroids) to understand how neurons find their final position in the brain and how they mature functionally. To investigate how different brain regions talk to each-other in normal and diseased states, we introduced a new approach for in vitro assembly of neural circuits, also known as assembloids.
    We employ state-of-the-art stem cell biology, genome engineering, imaging and neuroscience approaches to identify the dynamical processes that go awry in neural cells derived from patients with neuropsychiatric disorders, such as autism or schizophrenia, and what should be therapeutically targeted in these conditions.

  • Zara Patel

    Zara Patel

    Associate Professor of Otolaryngology/Head and Neck Surgery (Rhinology) and, by courtesy, of Neurosurgery at the Stanford University Medical Center

    BioDr. Zara M. Patel is Director of Endoscopic Skull Base Surgery and an Associate Professor of Otolaryngology and, by courtesy, of Neurosurgery at Stanford. She was born and raised in St. Louis, completed her MD at the Oregon Health and Sciences University in Portland, Oregon and completed her residency training in otolaryngology at Mount Sinai Medical Center in New York, NY. After pursuing fellowship training in rhinology and endoscopic skull base surgery at Stanford University, she was recruited to join the Emory University faculty in Atlanta in 2011. After four years, the rhinology division recruited her back to the West coast to rejoin the department here at Stanford University.

    Dr. Patel is an expert in advanced endoscopic sinus and skull base surgery. She treats patients with a wide variety of rhinologic complaints, including chronic sinus infection or inflammation, sinus disease that has failed medical therapy, sinus disease that has failed prior surgical therapy, cerebrospinal fluid leaks, benign and and malignant sinus and skull base tumors, as well as olfactory disorders.

    She is immediate past-Chair of the Education Committee and now Member of the Board of Directors for the American Rhinologic Society and has developed a multitude of educational materials for both physicians and patients to help them better understand rhinologic disorders. She is passionate about educating patients to allow them to make the best decisions about their own care, leading to better outcomes.

    Dr. Patel has published widely in topics such as avoiding complications in endoscopic sinus surgery, chronic rhinosinusitis in the immunosuppressed patient population, new devices and techniques for endoscopic skull base surgery, and olfactory dysfunction. She continues to perform research in these areas, and is beginning collaborative efforts with neuroscientists and engineers to develop technology that she hopes will eventually help cure patients with olfactory loss.

  • John M. Pauly

    John M. Pauly

    Reid Weaver Dennis Professor

    BioInterests include medical imaging generally, and magnetic resonance imaging (MRI) in particular. Current efforts are focused on medical applications of MRI where real-time interactive imaging is important. Two examples are cardiac imaging, and the interactive guidance of interventional procedures. Specific interests include rapid methods for the excitation and acquisition of the MR signal, and the reconstruction of images from the data acquired using these approaches.

  • Kim Butts Pauly

    Kim Butts Pauly

    Professor of Radiology (Radiological Sciences Lab) and, by courtesy, of Electrical Engineering and of Bioengineering

    Current Research and Scholarly InterestsWe are investigating and developing, and applying focused ultrasound in neuromodulation, blood brain barrier opening, and ablation for both neuro and body applications.

  • Roy Pea

    Roy Pea

    Director, H-STAR, David Jacks Professor of Education and Professor, by courtesy, of Computer Science

    Current Research and Scholarly Interestslearning sciences focus on advancing theories, research, tools and social practices of technology-enhanced learning of complex domains

  • Suzanne Pfeffer

    Suzanne Pfeffer

    Emma Pfeiffer Merner Professor in the Medical Sciences

    Current Research and Scholarly InterestsThe major focuses of our research is to understand the molecular basis of inherited Parkinson's Disease (PD) and to elucidate the molecular mechanisms by which proteins and cholesterol are transported between specific membrane compartments. We focus on the LRRK2 kinase that is inappropriately activated in PD and how it phosphorylates Rab GTPases, blocking the formation of primary cilia in culture and specific regions of the brain.

  • Sharon Pitteri

    Sharon Pitteri

    Associate Professor (Research) of Radiology (Cancer Early Detection-Canary Center)

    Current Research and Scholarly InterestsThe Pitteri laboratory is focused on the discovery and validation of proteins that can be used as molecular indicators of risk, diagnosis, progression, and recurrence of cancer. Proteomic technologies, predominantly mass spectrometry, are used to identify proteins in the blood that are differentially regulated and/or post-translationally modified with disease state. Using human plasma samples, tumor tissue, cancer cell lines, and genetically engineered mouse models, the origins of these proteins are being investigated. A major goal of this research is to define novel molecular signatures for breast and ovarian cancers, including particular sub-types of these diseases. This laboratory is also focused on the identification of proteins with expression restricted to the surface of cancer cells which can be used as novel targets for molecular imaging technologies.

  • Giles W Plant

    Giles W Plant

    Associate Professor of Neurosurgery

    Current Research and Scholarly InterestsOur research focuses on the repair of the injured spinal cord. We investigate the following areas:
    - Spinal cord injury (SCI): Axonal regeneration, myelination and gene therapy
    - Stem cell transplantation (adult, embryonic and iPS)
    - Endogenous stem cell activity after SCI

  • Kilian M Pohl

    Kilian M Pohl

    Associate Professor (Research) of Psychiatry and Behavioral Sciences (Public Mental Health and Population Sciences)

    Current Research and Scholarly InterestsThe foundation of the laboratory of Associate Professor Kilian M. Pohl, PhD, is computational science aimed at identifying biomedical phenotypes improving the mechanistic understanding, diagnosis, and treatment of neuropsychiatric disorders. The biomedical phenotypes are discovered by unbiased, machine learning-based searches across biological, neuroimaging, and neuropsychological data. This data-driven discovery currently supports the adolescent brain research of the NIH-funded National Consortium on Alcohol and NeuroDevelopment in Adolescence (NCANDA) and the Adolescent Brain Cognitive Development (ABCD), the largest long-term study of brain development and child health in the US. The laboratory also investigates brain patterns specific to alcohol use disorder and the human immunodeficiency virus (HIV) across the adult age range, and have advanced the understanding of a variety of brain diseases including schizophrenia, Alzheimer’s disease, glioma, and aging.

  • Russell Poldrack

    Russell Poldrack

    Albert Ray Lang Professor of Psychology and Professor, by courtesy, of Computer Science

    Current Research and Scholarly InterestsOur lab uses the tools of cognitive neuroscience to understand how decision making, executive control, and learning and memory are implemented in the human brain. We also develop neuroinformatics tools and resources to help researchers make better sense of data.

  • Ada Poon

    Ada Poon

    Associate Professor of Electrical Engineering

    Current Research and Scholarly InterestsOur research focuses on providing theoretical foundations and engineering platforms for realizing electronics that seamlessly integrate with the body. Such systems will allow precise recording or modulation of physiological activity, for advancing basic scientific discovery and for restoring or augmenting biological functions for clinical applications.

  • Matthew Porteus

    Matthew Porteus

    Professor of Pediatrics (Stem Cell Transplantation)

    Current Research and Scholarly InterestsGenome Editing and Population Dynamics for Gene Therapy and Cancer Research

  • Kathleen Poston, MD, MS

    Kathleen Poston, MD, MS

    Associate Professor of Neurology and, by courtesy, of Neurosurgery, at the Stanford University Medical Center

    Current Research and Scholarly InterestsMy research interests include the development, validation and application of functional and structural Neuroimaging techniques to be used as biomarkers for the diagnosis and treatment of movement disorders, such as Parkinson’s disease.

  • James Priest

    James Priest

    Assistant Professor of Pediatrics (Cardiology) at the Stanford University Medical Center

    Current Research and Scholarly InterestsThe Priest lab seeks a better understanding of the genetics and pathogenesis of congenital heart disease using translational genomics, big-data, and vertebrate models of cardiac development.

  • David Prince

    David Prince

    Edward F. and Irene Thiele Pimley Professor in Neurology and the Neurological Sciences

    Current Research and Scholarly InterestsExperiments examine
    1)intrinsic properties of neuronal membranes; actions of neurotransmitters that regulate neocortical and thalamic excitability
    2) chronic epileptogenesis following cortical injury; changes in intracortical connectivity and receptors;
    3) effects of early injury and activity on cortical development/maldevelopment Electrophysiological, anatomical and pharmacological techniques employed.
    4. prophylaxis of postraumatic epilepsy
    5. Neocortical interneuronal function/modulation