School of Humanities and Sciences


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  • Lynette Cegelski

    Lynette Cegelski

    Monroe E. Spaght Professor of Chemistry and Professor, by courtesy, of Chemical Engineering

    Current Research and Scholarly InterestsResearch in the Cegelski laboratory is driven by the need to uncover and define the chemistry that underlies outstanding challenges in human health, the environment, and sustainability. Beyond discovery, we use chemistry as a tool to innovate and create solutions to these pressing problems. The laboratory is highly interdisciplinary, designing experimental approaches to understand how complex biological systems are built, organized, and controlled, and then perturb and influence assembly processes. The lab develops new methods and uniquely leverages: (1) small molecules in new biochemical assay development, chemical genetics approaches, and therapeutic discovery in infectious diseases, (2) fluorescence and electron microscopy coupled to analytical HPLC, mass spectrometry, and complementary biochemical techniques, and (3) spectroscopy, particularly solid-state NMR, to uncover new “dark matter” and define chemistry in insoluble, heterogeneous and complex assemblies relevant to human health, plants, and the ocean.

    Long-standing efforts in the laboratory focus on defining mechanisms underlying bacterial biofilm formation and identifying new antibiotic and anti-virulence strategies, including advancing therapeutic candidates for the most difficult-to-treat infections. Through these efforts, we uncovered a new chemical structure in nature: phosphoethanolamine (pEtN) cellulose. Cellulose is the most abundant biopolymer on earth and this discovery provided the first experimental validation of a naturally produced chemically modified cellulose. We are developing alternatively modified celluloses and polysaccharides and advancing new solutions for ecofriendly, sustainably sourced, and recyclable materials. Collectively, our projects span disciplines from molecular structure and assembly chemistry to living microbial communities and natural marine systems, while aiming to translate fundamental discoveries into therapeutic and materials solutions.

  • Carlos Centeno Lairet

    Carlos Centeno Lairet

    Affiliate, Ethics In Society

    BioCarlos is a 2026 Ethics & Tech Practitioner Fellow at the McCoy Family Center for Ethics in Society. He co-founded SOMOS Civic Lab. At the lab, the team is researching and designing tools to democratize generative AI in Global Majority countries. Somos is part of the UNDP AI Trust & Safety Programme, and it's supported by the Pulitzer Center's AI Accountability program. As MIT Emerging Talent Director, he equips learners from migrant and refugee communities with computer science skills. He co-founded and directed MIT's Governance Innovation Initiative, as Associate Director of Innovation; co-designed and launched MIT's first Governance Innovation Research Fellowship, and hosted MIT's "Power to the Who" governance innovation podcast. He was previously at the UN for 10 years, where he worked in community and government preparedness to natural disasters based in Latin America, Asia and Africa. His AI (NLP) prototype ALIA was a Google launchpad finalist in Munich (2018). He has supported investigative journalism projects at Pro Publica on disappearances and detentions by the US federal government.

  • Giovanna Ceserani

    Giovanna Ceserani

    Professor of Classics

    Current Research and Scholarly InterestsIntellectual history, data science in the humanities, ancient and modern historiography, history of archaeology, early modern travels and explorations of the past

  • Chris Chafe

    Chris Chafe

    Duca Family Professor

    BioChris Chafe is a composer, improvisor, and cellist, developing much of his music alongside computer-based research. He is Director of Stanford University's Center for Computer Research in Music and Acoustics (CCRMA). In 2019, he was International Visiting Research Scholar at the Peter Wall Institute for Advanced Studies The University of British Columbia, Visiting Professor at the Politecnico di Torino, and Edgard-Varèse Guest Professor at the Technical University of Berlin. At IRCAM (Paris) and The Banff Centre (Alberta), he has pursued methods for digital synthesis, music performance and real-time internet collaboration. CCRMA's jacktrip project involves live concertizing with musicians the world over. Online collaboration software and research into latency factors continue to evolve. An active performer either on the net or physically present, his music reaches audiences in sometimes novel venues. An early network project was a simultaneous five-country concert was hosted at the United Nations in 2009. Chafe’s works include gallery and museum music installations which are now into their second decade with “musifications” resulting from collaborations with artists, scientists and MD’s. Recent work includes the Earth Symphony, the Brain Stethoscope project (Gnosisong), PolarTide for the 2013 Venice Biennale, Tomato Quintet for the transLife:media Festival at the National Art Museum of China and Sun Shot played by the horns of large ships in the port of St. Johns, Newfoundland.