School of Medicine
Showing 4,491-4,500 of 5,030 Results
-
Christina (Christy) Tise, MD, PhD
Assistant Professor of Pediatrics (Genetics) and, by courtesy, of Obstetrics & Gynecology (Reproductive Endocrinology and Infertility)
BioDr. Christina (Christy) Tise is a physician scientist and Assistant Professor in the Division of Medical Genetics at Stanford with subspecialty training in Clinical Biochemical Genetics. Dr. Tise has developed multiple research projects focused on the clinical impact of biochemical genetic conditions in pregnancy and newborn health, including a project focused on unforeseen diagnoses in individuals initially identified through state newborn screening which has resulted in a number of publications.
Dr. Tise also researches the genetic etiologies of recurrent pregnancy loss and the impact of inherited metabolic conditions on human reproduction. She is involved in several research initiatives including contributing to the development of TRIOS, a multi-site, NIH-funded research study to evaluate the genetic causes of recurrent pregnancy loss. In serving as the primary research mentor for a recent Masters of Genetic Counseling graduate, Dr. Tise’s research on carrier and newborn screening has highlighted areas of ancestry-related healthcare inequities specific to the field of Medical Genetics.
Dr. Tise’s primary academic and advocacy interests are embodied in this work, specifically the overlap between biochemical and molecular analysis, and the clinical utility of innovative technologies for diagnosis and treatment of genetic disease. This is an unbelievably thrilling time for the field of Medical Genetics, as it promises immense progress and opportunity for all fields of medicine, and Dr. Tise is determined, honored, and incredibly excited to be a part of it!
Research interests: newborn screening, carrier screening, prenatal screening, genetics of recurrent pregnancy loss, biochemical genetics, novel gene discovery, variant interpretation, founder populations, diagnostic genetic testing, bioethics, GWAS/ExWAS -
Sara L. (Sally) Tobin
Sr Research Scholar, Pediatrics - Center for Biomedical Ethics
Current Research and Scholarly InterestsTobin is a Senior Research Scholar at the Stanford Center for Biomedical Ethics. She obtained her Ph.D. in Developmental Biology from the University of Washington and did postdoctoral research in Genetics at the University of California, Berkeley and in Biochemistry at the University of California, San Francisco. She became a faculty member at the University of Oklahoma College of Medicine in 1983 and moved to Stanford University in 1996. Her research contributions have been published in prestigious journals such as Cell, Nature, Genes & Development, Neuron, and Journal of Cell Biology.
Projects
With her collaborator, graphic designer Ann Boughton, Tobin has completed the production of three educational multimedia CD-ROM discs about the genetic revolution in medical care sparked by the rapid advances in our knowledge about the human genome. An on-line version derived and updated from these CDs is pending release through Twisted Ladder Media, and is entitled: "The New Genetics: Medicine and the Human Genome. Molecular Concepts, Applications, and Ramifications." In addition, Tobin and Boughton have collaborated on educational websites on inherited risk of breast cancer and on hereditary colorectal cancer with the Stanford Cancer Genetics Clinic.
Tobin's current major research interests include an educational project funded by the National Science Foundation to create and evaluate innovative modules for undergraduates entitled, "The New Genetics: Electronic Tools for Educational Innovation." The modules are presented in on-line form as an electronic course and are accompanied by workbook exercises and problem sets. The content includes principles of genetics, molecular genetic technologies, applications in medicine, environmental biology, agriculture, and society, as well as implications. In addition, she is collaborating on two projects that are exploring the ramifications of using genetic information about addiction risk in the judicial system.
Tobin is a member of the Benchside Consultation Team for the Center for the Integration of Research on Genetics and Ethics, and she evaluates clinical protocols for ethical issues for the Clinical Translational Research Program. -
Andreas Tolias
Professor of Ophthalmology
BioAndreas Tolias is a faculty member at Stanford University, where he co-leads the Enigma Project. His research lies at the interface of neuroscience and AI, combining large-scale neuroscience experiments with machine learning to uncover the principles of natural intelligence. By focusing on perceptual inference and decision-making, his lab integrates systems and computational neuroscience with AI to decipher the network-level principles of intelligence. Dr. Tolias’s work aims to reverse-engineer these principles to create AI systems that are smarter, more robust, trustworthy, and efficient, while providing a powerful platform to test brain algorithms under complex natural tasks. He earned his B.A. and M.A. in Natural Sciences from the University of Cambridge, a Ph.D. in Systems and Computational Neuroscience from MIT, and completed postdoctoral training in Neuroscience and Machine Learning at the Max Planck Institute for Biological Cybernetics in Tübingen.
-
Kimberley Tolias
Professor (Research) of Anesthesiology, Perioperative and Pain Medicine
Current Research and Scholarly InterestsThe human brain is composed of billions of neurons connected through trillions of synapses that form the neural circuits underlying thought, emotion, learning, memory, and behavior. These synaptic connections are not static - they are continuously shaped and remodeled throughout life in response to experience, a processes critical for learning and memory. When neural circuits fail to develop or function properly, the consequences can be devastating, contributing to conditions ranging from autism spectrum disorder and intellectual disability to chronic pain, depression, schizophrenia, Alzheimer's disease, and cognitive decline.
Research in the Tolias laboratory seeks to understand the fundamental molecular and cellular mechanisms that govern how neural circuits form, adapt, and repair themselves in the mammalian central nervous system (CNS). Our work focuses on how neurons sense signals from their environment and convert them into intracellular signaling pathways that drive synapse formation and remodeling, dendritic and axonal growth, and cell migration. We are also interested in how disruption of these pathways contributes to neurological and neuropsychiatric disease, and whether targeting specific signaling mechanisms can promote recovery following CNS injury or disease.
The laboratory combines mouse genetics with molecular, cellular, biochemical, electrophysiological, genomic, and behavioral approaches to bridge fundamental neuroscience with translational discovery.
Current Research Areas:
- Molecular mechanisms regulating synapse development, neural circuit formation, and synaptic plasticity during learning and memory
- Roles of Rho GTPase signaling pathways in brain development, circuit remodeling, and neurological disease
- Functions of Adhesion-GPCRs in synapse development, dendritic and axonal growth, and neural circuit function
- Mechanisms underlying chronic pain, opioid tolerance, and chronic pain-associated mood and cognitive disorders
- Synaptic and circuit dysfunction following traumatic brain injury, radiotherapy, and other CNS injuries
- Development of new tools to visualize and map synaptic remodeling during learning and disease
- Interactions between the gut microbiome, brain development, neural circuit function, and behavior -
Lucy Tompkins
Lucy Becker Professor of Medicine, Emerita
Current Research and Scholarly InterestsGenetic and cellular basis of pathogenicity of Helicobacter pylori. Molecular epidemiology, hospital epidemiology, quality improvement in healthcare associated infections.
-
Hui Qi Tong
Clinical Professor, Psychiatry and Behavioral Sciences - Medical Psychiatry
BioClinical Professor, Stanford Department of Psychiatry & Behavioral Sciences
Clinical Associate Professor, Stanford Department of Psychiatry & Behavioral Sciences
HS Clinical Assistant Professor, UCSF Department of Psychiatry & San Francisco VA Health Care
Staff Psychologist: Women's Mental Health Program, San Francisco VA Health Care System
Academic visitor: Oxford Mindfulness Center, Department of Psychiatry, Oxford University
Psychology Post-doctoral Fellowship: UCSF/San Francisco VA Health Care System
Psychology Pre-doctoral Internship: UCSF/San Francisco VA Health Care System
Psychology Education: Pacific Graduate School of Psychology, Palo Alto University (2008)
Clinical Research Associate: Department of Psychiatry, Tufts University School of Medicine
Research Fellow: Genetics Division, Department of Medicine, Boston Children's Hospital,Harvard Medical School
Medical Education: Fudan University, Shanghai Medical College, Shanghai, China (1994)
