School of Medicine
Showing 921-930 of 5,114 Results
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Ximena Corso Díaz
Assistant Professor of Ophthalmology
Current Research and Scholarly InterestsWe are interested in unraveling the roles of RNA-binding proteins (RBPs) and regulatory RNAs in retinal development and homeostasis.
RNA-binding proteins mediate functional integration of transcriptional and post-transcriptional machineries influencing various aspects of gene expression and RNA metabolism. Several RBPs have cell-type enriched expression patterns in the retina or cause blinding diseases, however their role in retinal development and function is poorly understood. We have identified several RBPs that interact with the photoreceptor-specific transcription factor NRL and are likely involved in development and homeostasis of this retinal cell-type. We are pursuing the following lines of research:
1) RBPs in retinal development and degeneration. We will study the role of RBPs in regulating retinal development and maintaining homeostasis. We will focus on RBPs enriched in the retina, their interactions with retinal transcription factors like NRL, and their relevance to retinal diseases.
2) RBPs in R-loop regulation in the retina. R-loops are triple-stranded structures created when RNA anneals to one of the strands of the DNA duplex. R-loops have many regulatory roles during gene expression and their dysregulation can be detrimental to genome integrity. We observed that R-loops are dynamic during retinal development and identified key R-loop-associated RBPs that are enriched in rod photoreceptors and that interact with the transcription factor NRL. We will study the role of R-loops and their regulatory RBPs in retinal development and homeostasis.
3) Chromatin-associated regulatory RNAs through the retina lifespan. Chromatin-associated RNAs contribute to the dynamic regulation of gene expression, chromatin structure, and genome organization, playing essential roles in various biological processes, including development, differentiation, and disease. We will study how regulatory RNAs, together with their cognate RBPs, influence expression programs and chromatin dynamics through the retina lifespan. -
Victoria Cosgrove
Assistant Professor of Psychiatry and Behavioral Sciences (Child and Adolescent Psychiatry and Child Development)
Current Research and Scholarly InterestsDr. Cosgrove studies putative roles for life and family stress as well as inflammatory and neurotrophic pathways in the etiology and development of mood disorders across the life span.
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Alexandra Cours, MD
Clinical Assistant Professor, Medicine - Primary Care and Population Health
BioDr. Cours is a clinician educator in Geriatric Medicine at Stanford University, providing primary care for older adults and serving as a geriatric medicine consultant at Stanford Hospital. As Medical Director of the Acute Care for Elders (ACE) Unit, she leads specialized care for hospitalized older adults to optimize outcomes. She is also the Geriatric Section Director for Age-Friendly Health Systems, leading clinical and strategic efforts to advance age-friendly, evidence-based care across hospital settings and overseeing quality-improvement initiatives, including a delirium-reduction program. Dr. Cours leads a personal and professional development program for geriatrics fellows that prepares them for the transition to independent practice. In addition, she participates in the Foundations of Academic Clinical Excellence and Transformation (FACET) Faculty Development Fellowship and the Clinician Educator Scholars (CE Scholars) Program, which develop clinician expertise in ecosystem awareness, quality improvement, education, and clinical informatics through mentored initiatives that culminate in publishable work and career growth.
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Jesse Courtier
Adjunct Clinical Professor, Radiology - Pediatric Radiology
BioPrior to joining Stanford and Lucille Packard Children's Hospital, Dr. Jesse Courtier was Professor and Chief of Pediatric Radiology at UCSF Benioff Children’s Hospital, San Francisco. He is the author of over 70 peer reviewed articles with more than 3000+ citations. Dr. Courtier is a multi-award-winning educator and innovator. He is also an entrepreneur, startup mentor, and healthcare investor.
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Markus Covert
Shriram Chair of the Department of Bioengineering, Professor of Bioengineering and, by courtesy, of Chemical and Systems Biology
Current Research and Scholarly InterestsOur focus is on building computational models of complex biological processes, and using them to guide an experimental program. Such an approach leads to a relatively rapid identification and validation of previously unknown components and interactions. Biological systems of interest include metabolic, regulatory and signaling networks as well as cell-cell interactions. Current research involves the dynamic behavior of NF-kappaB, an important family of transcription factors.
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Robert P. Cowan, MD, FAAN, FAHS
Clinical Professor (By courtesy), Anesthesiology, Perioperative and Pain Medicine
Current Research and Scholarly InterestsCurrent interest focus on patient education technology and patient/physician communication with a particular emphasis on tools which increase encounter efficiency and improve outcomes. Basic research focuses on mechanisms of action in Chronic Daily Headache, with a particular emphasis on New Daily Persistent Headache. Techniques include fMRI, biomarker investigation and evoked potentials. Clinical research includes clinical trials of novel treatments for episodic and chronic headache forms.
