School of Medicine
Showing 41-50 of 105 Results
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Hyunkyung Claire Kim
Postdoctoral Scholar, Endocrinology and Metabolism
BioHyunkyung Claire Kim is a Postdoctoral Research Scholar in the Translational Genomics of Diabetes Lab led by Dr. Anna Gloyn. She received her PhD in Genetics from the University of Chicago, where she developed a statistical method to disentangle shared and trait-specific genetic architecture across complex diseases using large-scale biobank data. Prior to her doctoral training, she worked at Massachusetts General Hospital, studying the genetic subtypes and heterogeneity of type 2 diabetes through data-driven clustering approaches.
She is interested in the translational genomics of diabetes, including integrating human genetics with multi-omic data to uncover disease mechanisms and advance precision medicine. Her long-term research interests include developing computational methods to understand how genetic, molecular, and environmental factors jointly shape metabolic disease risk, disease heterogeneity, and progression. -
Mauro Lago Docampo
Postdoctoral Scholar, Cardiology
Current Research and Scholarly InterestsI have always been fascinated by the process of genetic penetrance, how two people can carry the same mutation but only one of them may be affected.
My main project focuses on understanding the role of TBX4 in the development of Pulmonary Arterial Hypertension (PAH). Mutations in this gene are related to very different diseases. In my research, I mix cellular models, gene editing, and high throughput assays to find the determinants of penetrance in the development of PAH under these conditions. -
Yunkyeong Lee
Postdoctoral Scholar, Endocrinology and Metabolism
BioYun is a postdoctoral research scholar in the Translational Genomics of Diabetes Laboratory under the mentorship of Dr. Anna Gloyn. Since joining the lab in August 2022, she has been investigating type 2 diabetes (T2D) susceptible genes and their molecular mechanisms in pancreatic β-cell dysfunction and the development of T2D. Her primary focus is on how T2D effector transcripts alter autophagy/mitophagy pathways in human pancreatic β-cells, contributing to β-cell failure, mitochondrial dysfunction, and T2D pathology. She also investigated the impact of genetic mutations underlying neonatal diabetes using CRISPR HDR knockin genome editing in human induced pluripotent stem cell (hiPSC) models and their derivatives.
During her PhD, she explored the role of an epigenetic regulator and its molecular machinery in the pathogenesis of non-alcoholic fatty liver disease (NAFLD), now termed metabolic dysfunction-associated steatotic liver disease (MASLD). In parallel, she studied the interplay between endoplasmic reticulum (ER) stress-mediated unfolded protein response (UPR) signalling and autophagy, and examined how these processes are modulated by bioactive plant extracts in various cellular contexts.
She is particularly interested in exploring inter-organ communication, such as pancreas-liver crosstalk, and how these interactions influence systemic metabolism and contribute to the onset and progression of T2D, along with its complications. Her long-term research goal is to advance our understanding of the cellular and molecular mechanisms driving T2D and to identify novel therapeutic targets and strategies.
