Genetics
Showing 21-30 of 365 Results
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Maria Barna
Associate Professor of Genetics
Current Research and Scholarly InterestsThe Barna Lab studies how gene expression is controlled at the level of translation to shape development, regeneration, and disease.For decades, ribosomes were viewed as uniform molecular machines that passively translate genetic information. Our work helped overturn this paradigm by demonstrating that ribosomes can differ in composition and function, giving rise to specialized translation programs that regulate cell fate and organismal development. By integrating genomics, mass spectrometry,
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Greg Barsh
Professor of Genetics and of Pediatrics, Emeritus
Current Research and Scholarly InterestsGenetics of color variation
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Michael Bassik
Associate Professor of Genetics
Current Research and Scholarly InterestsWe are an interdisciplinary lab focused on two major areas:(1) we seek to understand mechanisms of cancer growth and drug resistance in order to find new therapeutic targets(2) we study mechanisms by which macrophages and other cells take up diverse materials by endocytosis and phagocytosis; these substrates range from bacteria, viruses, and cancer cells to drugs and protein toxins. To accomplish these goals, we develop and use new technologies for high-throughput functional genomics.
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Jon Bernstein
Professor of Pediatrics (Genetics) and, by courtesy, of Genetics
Current Research and Scholarly InterestsMy research is focused on the diagnosis, discovery and delineation of rare genetic conditions with a focus on neurodevelopmental disorders. This work includes the application of novel computational methods and multi-omics profiling (whole genome sequencing, long-read DNA sequencing, RNA sequencing, methylomics, metabolomics). I additionally participate in an interdisciplinary project to develop induced pluripotent stem cell and assembloid models of genetic neurodevelopmental disorders.
