Institute for Stem Cell Biology and Regenerative Medicine
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The Ernest and Amelia Gallo Professor in the School of Medicine, Professor of Developmental Biology and, by courtesy, of Chemical and Systems Biology
Current Research and Scholarly InterestsFunction of Hedgehog proteins and other extracellular signals in morphogenesis (pattern formation), in injury repair and regeneration (pattern maintenance). We study how the distribution of such signals is regulated in tissues, how cells perceive and respond to distinct concentrations of signals, and how such signaling pathways arose in evolution. We also study the normal roles of such signals in stem-cell physiology and their abnormal roles in the formation and expansion of cancer stem cells.
Postdoctoral Research Fellow, Stem Cell Biology and Regenerative Medicine
Current Research and Scholarly InterestsMy long-term goal is to generate whole human organs in large research animals, which will be universally immune compatible and ready for human transplantation.
MD Student, expected graduation Spring 2018
Ph.D. Student in Stem Cell Biology and Regenerative Medicine, admitted Autumn 2012
Current Research and Scholarly InterestsAging, rejuvenation, exercise, stem cells, cancer, metabolism