Maternal & Child Health Research Institute (MCHRI)
Showing 171-180 of 996 Results
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Ruben J Colman, MD, PhD
Assistant Professor of Pediatrics (Gastroenterology)
BioDr. Colman is a pediatric gastroenterologist and physician-scientist with an overarching goal to improve and optimize the quality of care and outcomes for children with inflammatory bowel diseases (IBD) through precision medicine approaches. His interdisciplinary team science research program focuses on making precision medicine clinically actionable through innovative solutions merging clinical pharmacology knowledge with ‘-omics’ discoveries using microbiome and metabolomics signatures. Part of this work includes translating these findings into improved clinical treat-to-target endpoints with immediate noninvasive point-of-care measures such as intestinal ultrasound.
The foundation of his current work originates from his PhD titled ‘Precision Dosing and Personalized Medicine in pediatric IBD’. During his training, Dr. Colman was also an American Gastroenterological Association (AGA) editorial fellow for Gastroenterology and he is actively involved in the committees of several professional societies including the North American Society for Pediatric Gastroenterology, Hepatology and Nutrition (NASPGHAN), the Crohn’s and Colitis Foundation and the International Bowel UltraSound (IBUS) Group. Dr. Colman is supported by a Career Development K23 Award from the NIH, which focuses on evaluating personalized treatment strategies for children with Crohn's disease, specifically examining microbial and transmural intestinal ultrasound findings. He is also funded by awards of the NASPGHAN Foundation and the Stanford Pediatrics Physician-Scientist Bridge to K Program. -
Christopher H. Contag
Professor of Pediatrics (Neonatology), Emeritus
Current Research and Scholarly InterestsWe develop and use the tools of molecular imaging to understand oncogenesis, reveal patterns of cell migration in immunosurveillance, monitor gene expression, visualize stem cell biology, and assess the distribution of pathogens in living animal models of human biology and disease. Biology doesn't occur in "a vacuum" or on coated plates--it occurs in the living body and that's were we look for biological patterns and responses to insult.
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John P. Cooke, MD, PhD
Professor of Medicine (Cardiovascular Medicine), Emeritus
Current Research and Scholarly InterestsOur translational research program in vascular regeneration is focused on generating and characterizing vascular cells from human induced pluripotential stem cells. We are also studying the therapeutic application of these cells in murine models of peripheral arterial disease. In these studies we leverage our longstanding interest in endothelial signaling, eg by nitric oxide synthase (NOS) as well as by nicotinic cholinergic receptors (nAChR).
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Margaret Cooke, MD
Clinical Assistant Professor, Orthopaedic Surgery
BioDr. Cooke is a clinical assistant professor in the Department of Orthopaedic Surgery at Stanford University School of Medicine. She has a strong clinical interest in hand, wrist, and elbow surgery for adult and pediatric patients. She is dual fellowship trained in Hand & Upper Extremity Surgery and Pediatric & Congenital Hand Surgery.
As an orthopaedic surgeon, Dr. Cooke’s goal is to alleviate pain and improve hand, wrist, and elbow function so that her patients can return to the activities they enjoy. Her primary clinical interests are nerve compression (carpal tunnel), nerve injuries (traumatic/lacerations), joint instability/arthritis (degenerative conditions of the hand wrist and elbow), sports/athletic injuries, fracture care, and pediatric & congenital conditions of the hand and upper extremity.
Dr. Cooke utilizes a multi-disciplinary approach in order to provide comprehensive care for each patient. She works closely with colleagues from oncology, radiology, physical therapy, and other specialties. Her team includes certified hand therapists, cast technicians, medical assistants, and patient care coordinators. Together, Dr. Cooke and her team are committed to providing the best possible care for patients.
She invites patient referrals as early as possible when an upper extremity problem is suspected. She ensures a trusting relationship with referring physicians (whether primary care providers or specialists) by staying in communication so they understand and are comfortable with her recommendations.
In addition to patient care, Dr. Cooke has enjoyed contributing to her field through research. Among Dr. Cooke’s clinical research interests is fracture healing, including gene expression following administration of medication to stimulate bone repair. She has authored articles on topics like infection prediction and pain management after surgical repair of fractures. Her work has appeared in the Journal of Orthopaedic Trauma, Journal of Orthopaedic Research, Osteoarthritis & Cartilage, Spine, and Transplantation. She also co-wrote the chapter “The History of Carpal Tunnel” for the textbook Carpal Tunnel Syndrome and Related Median Neuropathies.
Dr. Cooke’s honors include a Howard Hughes Research Fellowship, an Outstanding Chief Resident Research Award, and recognition for authoring one of the top ten Foot & Ankle research papers at the 2016 American Academy of Orthopaedic Surgeons conference.
In addition to her practice in the U.S., Dr. Cooke has traveled abroad as a physician volunteer to provide surgical services in underserved areas where there is no access to hand surgery specialists. In partnership with the surgeon-founded nonprofit organization Touching Hands, she has performed hand surgeries on adult and pediatric patients in Honduras. Dr. Cooke also has traveled with Shriners Hospital to treat children in Davao, Philippines. -
David N. Cornfield
Anne T. and Robert M. Bass Professor of Pediatric Pulmonary Medicine
Current Research and Scholarly InterestsOver the past 20 years, the Cornfield Laboratory has focused upon basic, translational and clinical research, with a primary focus on lung biology. As an active clinician-scientist, delivering care to acutely and chronically ill infants and children, our lab focuses on significant clinical challenges and tried to use science to craft novel solutions to difficult clinical problems.
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Steven M. Corsello
Assistant Professor of Medicine (Oncology)
Current Research and Scholarly InterestsOur laboratory operates at the intersection of functional genomics and chemical biology, with the goal of advancing novel molecular mechanisms of cancer inhibition to clinical use. We aim to 1) leverage phenotypic screening and functional genomics to determine novel anti-cancer mechanisms of small molecules, 2) develop new targeted therapy approaches against solid tumors, and 3) build a comprehensive community resource for drug repurposing discovery.
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Victoria Cosgrove
Assistant Professor of Psychiatry and Behavioral Sciences (Child and Adolescent Psychiatry and Child Development)
Current Research and Scholarly InterestsDr. Cosgrove studies putative roles for life and family stress as well as inflammatory and neurotrophic pathways in the etiology and development of mood disorders across the life span.
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Helio Costa
Affiliate, Biomedical Informatics (BMI) graduate training program
BioHelio Costa, PhD, is a medical geneticist specializing in oncology, genomics, computational biology, data science, artificial intelligence, and product development. His work focuses on developing new cancer therapies and medical software to improve cancer patient care. He currently serves as Senior Medical Director and Head of Molecular Therapeutics & Drug Development at Natera and is an Adjunct Clinical Assistant Professor in the Department of Pathology at Stanford Medical School.
Dr. Costa’s research spans the entire drug development pipeline, from discovery to FDA-approved therapies. He leads efforts in developing innovative cancer treatments by integrating advanced genomics, computational biology, and AI-driven methodologies. His team focuses on the creation of targeted molecular therapeutics, using large-scale genetic data to identify novel treatment pathways and predict patient responses. In addition to drug discovery, Dr. Costa oversees the clinical trials necessary for validating these therapies, ensuring they meet rigorous standards for safety and efficacy. Furthermore, he manages the product development and commercialization process, guiding new treatments from initial research through to market-ready, FDA-approved cancer therapies.
In addition to his therapeutic work, Dr. Costa has led the development and implementation of genetic diagnostic tests and clinical algorithms used to support therapeutic decisions at Stanford Health Care. His contributions include the creation of DNA and RNA cancer diagnostic tests, as well as algorithms that analyze large-scale laboratory datasets and electronic medical records to predict patient outcomes. As a co-investigator with the NIH Clinical Genome Resource (ClinGen) Consortium, Dr. Costa oversaw developing FDA-recognized medical software used by healthcare providers, researchers, and biotech companies to assess the clinical relevance of genes and mutations.
He is the founding director of the Stanford Clinical Data Science Fellowship, where post-doctoral medical fellows engage in interdisciplinary clinical research and implement real-world health data solutions within Stanford Health Care. Dr. Costa is also an Attending Medical Geneticist for the Molecular Genetic Pathology Laboratory at Stanford Health Care, where he previously served as Assistant Lab Director.
Dr. Costa holds a BS in Genetics from the University of California, Davis, a PhD in Genetics from Stanford University School of Medicine, and completed his ABMGG Clinical Molecular Genetics and Genomics fellowship training at Stanford University School of Medicine.
