Maternal & Child Health Research Institute (MCHRI)
Showing 501-520 of 1,008 Results
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Christopher Lee-Messer, MD, PhD
Clinical Associate Professor, Pediatric Neurology
Clinical Associate Professor (By courtesy), PediatricsCurrent Research and Scholarly InterestsMy chief clinical focus is in pediatric epilepsy, especially how epilepsy affects learning and development. For my research, I background in neural development and computational neuroscience towards developing better learning algorithms and applying the latest techniques in machine learning for better diagnosis and treatment of disease.
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John Leikauf
Clinical Associate Professor, Psychiatry and Behavioral Sciences - Child & Adolescent Psychiatry and Child Development
Current Research and Scholarly InterestsI am interested in better understanding the heterogeneous cognitive and electrophysiological abnormalities in children with ADHD and the many other conditions that commonly co-occur with ADHD. The long-term goal is to be able to better target treatments to specific deficits in order to promote long-term health and well-being and improve outcomes that matter to individuals and families suffering from these disorders.
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Mary Leonard
Arline and Pete Harman Professor, Professor of Pediatrics (Nephrology), of Medicine (Nephrology) and, by courtesy, of Epidemiology and Population Health
Current Research and Scholarly InterestsMy multidisciplinary research program is focused on (1) the detrimental effects of glucocorticoids, sarcopenia and inflammation on bone development in pediatric diseases, (2) the long-term effects of childhood cancer on bone and muscle quality, (3) the assessment of renal osteodystrophy using novel micro-imaging techniques, (4) the effects of vitamin D deficiency on physical function and cardiovascular disease, and (5) the evaluation of biomechanical interventions as anabolic bone therapies.
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Stephanie A. Leonard
Assistant Professor (Research) of Obstetrics and Gynecology (Maternal Fetal Medicine) and, by courtesy, of Anesthesiology, Perioperative & Pain Medicine, and of Epidemiology and Population Health
BioStephanie Leonard, PhD, MS, is an Assistant Professor in the Dunlevie Maternal-Fetal Medicine Center for Discovery, Innovation, and Clinical Impact (https://dunleviemfm.stanford.edu/) and holds courtesy appointments in Anesthesiology, Perioperative and Pain Medicine and in Epidemiology and Population Health.
The goal of Dr. Leonard’s research is to advance positive health outcomes and experiences for pregnant individuals and newborns. She is interested in applying transdisciplinary methods to perinatal health research, with a focus on studying pregnancy-related morbidities in large data sources. Currently, her primary research interests are in utilizing large electronic health record datasets to conduct multi-site studies on chronic health condition treatments during pregnancy. To this end, she co-launched the OHDSI Pregnancy and Reproductive Health Work Group (https://www.ohdsi.org/workgroups/) and collaborates closely with the Harvard Program on Perinatal and Pediatric Pharmacoepidemiology (http://www.harvardpreg.org/). She also serves as a collaborator and mentor on a variety of obstetrics studies, including clinical trials, prospective and retrospective observational studies, and qualitative studies. Dr. Leonard's research program is currently funded by NHLBI (K01) and NICHD (U54).
Dr. Leonard trained in epidemiology at UCLA (MS) and UC Berkeley (PhD), where her research focused on nutrition in pregnancy. She completed a postdoc in Neonatal and Developmental Medicine at Stanford as part of the Stanford Center for Population Health Sciences. -
Marc Levenston
Associate Professor of Mechanical Engineering and, by courtesy, of Radiology (Radiological Sciences Laboratory)
Current Research and Scholarly InterestsMy lab's research involves the function, degeneration and repair of musculoskeletal soft tissues, with a focus on meniscal fibrocartilage and articular cartilage. We are particularly interested in the complex interactions between biophysical and biochemical cues in controlling cell behavior, the roles of these interactions in degenerative conditions such as osteoarthritis, and development of tissue engineered 3D model systems for studying physical influences on primary and progenitor cells.
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Maayan Levy
Assistant Professor of Pathology
Current Research and Scholarly InterestsThe Levy Lab studies how microbiome-brain interactions influence metabolism, behavior, and disease. By investigating how microbial signals affect neural circuits, we explore mechanisms underlying obesity, diabetes, and psychiatric conditions. The lab seeks to uncover new therapeutic targets using advanced neuroscience tools like optogenetics and imaging. Our research aims to improve understanding of how microbiome imbalances contribute to disease and how restoring balance can promote health.
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David B. Lewis
Naddisy Foundation Professor of Pediatric Food Allergy, Immunology, and Asthma
Current Research and Scholarly InterestsMy laboratory is focused on defining cellular and molecular mechanisms that limit T cell responses to vaccines and pathogens during normal early postnatal development and in cases of inherited genetic immunodeficiencies. We are also determinomg how these limitations in immunity can be overcome by using novel approaches for vaccine adjuvants for influenza vaccine and by using catalytically inactive Cas proteins for inducing endogenous gene expression.
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Gordon Li, MD
Professor of Neurosurgery and, by courtesy, of Neurology and Neurological Sciences and of Otolaryngology - Head & Neck Surgery (OHNS)
Current Research and Scholarly Interests1.) My laboratory studies the biology of brain tumors with the goal of developing novel therapeutics for the treatment of malignant brain tumors and translating that research into clinical trials.
2.) My clinical interests include improving surgical techniques for brain tumor surgery, immunotherapy for the treatment of glioblastoma, and novel uses for stereotactic radiosurgery. -
Jin Billy Li
Professor of Genetics
Current Research and Scholarly InterestsThe Li Lab is primarily interested in RNA editing mediated by ADAR enzymes. We co-discovered that the major function of RNA editing is to label endogenous dsRNAs as "self" to avoid being recognized as "non-self" by MDA5, a host innate immune dsRNA sensor, leading us to pursue therapeutic applications in cancer, autoimmune diseases, and viral infection. The other major direction of the lab is to develop technologies to harness endogenous ADAR enzymes for site-specific transcriptome engineering.
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Joseph C. Liao
Kathryn Simmons Stamey Professor
Current Research and Scholarly InterestsThe overarching theme of my scholarship is to develop precision diagnostics in imaging and biomarkers to guide the delivery of precision therapy for urological diseases including bladder cancer, urinary tract infections, and kidney stone disease.
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Ronglih Liao
Douglass M. and Nola Leishman Professor of Cardiovascular Disease
BioDr. Liao is a Professor of Medicine and co-Director of Stanford Cardiac Amyloid Center. The major goal of her research program focuses on understanding the mechanisms that underlie the pathophysiology of heart failure and developing novel treatments to combat this process. Her laboratory has played an international leading role in the study of amyloid light chain (AL) cardiomyopathy, a rare and fatal form of cardiovascular disease. We have described the underlying pathophysiologic basis for amyloid cardiomyopathy and found that the circulating amyloidogenic light chain proteins that characterize this disease directly result in a specific cardiotoxic response. Consequently, our research work has redefined AL cardiomyopathy and has raised new treatment approaches. More recently, her research efforts have expanded to include transthyretin (ATTR) cardiac amyloidosis.
In line with her goal of revealing novel therapeutic strategies for patients with cardiovascular disease, our efforts have also focused on characterizing and harnessing endogenous cardiac regenerative mechanisms. Her laboratory initially demonstrated the therapeutic potential of exogenous primitive muscle cells delivered to the injured heart. This work was among the earliest milestones in the field and served as the basis for an international trial of cell-based therapy. Subsequently, Liao lab identified and characterized a population of cardiac progenitor cells and its relationship and dynamic activity following cardiac injury in the adult heart. Her laboratory aims to reveal the molecular mechanisms regulating the endogenous regenerative capacity of the heart and to harness such repair mechanisms for the treatment of cardiovascular disease. Dr. Liao has lectured extensively on both amyloid cardiomyopathy and stem cell biology, and have maintained a history of independent NIH funding in these areas for more than two decades.
Over the course of her academic career, she has taken the greatest pride in mentoring the next generation of scientists. Dr. Liao has had the privilege to supervise several dozen students, postdoctoral fellows, and junior faculty, many of whom have gone on to independent academic careers at the highest institutions. Her contribution to the advancement of scientific knowledge also includes lecturing at various university and academic institutions as well as at scores of conferences and symposia locally, nationally, and internationally. -
Y. Joyce Liao, MD, PhD
Stanford Medicine Professor of Ophthalmology and Professor of Neurology and Neurological Sciences
Current Research and Scholarly InterestsIschemic optic neuropathy
Stem cell transplantation
Optic neuropathy
Optic neuritis
Eye movement disorders
Reading
Parkinson's disease
Multiple sclerosis
