Maternal & Child Health Research Institute (MCHRI)
Showing 21-40 of 75 Results
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Melanie Hayden Gephart
Professor of Neurosurgery and, by courtesy, of Neurology and Neurological Sciences
BioI am a brain tumor neurosurgeon, treating patients with malignant and benign tumors, including gliomas, brain metastases, meningiomas, and schwannomas. I direct the Stanford Brain Tumor Center and the Stanford Brain Metastasis Consortium, collaborative unions of physicians and scientists looking to improve our understanding and treatment of brain tumors. My laboratory seeks greater understanding of the mechanisms driving tumorigenesis and disease progression in malignant brain tumors. We study how rare cancer cell populations survive and migrate in the brain, inadvertently supported by native brain cells. We develop novel cerebrospinal fluid-based biomarkers to track brain cancer treatment response, relapse, and neurotoxicity. Our bedside-to-bench-to-bedside research model builds on a foundation of generously donated patient samples, where we test mechanisms of brain cancer growth, develop novel pre-clinical models that reliably recapitulate the human disease, and facilitate clinical trials of new treatments for patients with brain cancer.
www.GephartLab.com
https://stan.md/BrainMets
@HaydenGephartMD -
John P. Hegarty II
Clinical Assistant Professor, Psychiatry and Behavioral Sciences
BioI am a neuroscientist and Principal Investigator of the Stanford Clinical Neuroscience (CNS) Lab in the Department of Psychiatry and Behavioral Sciences as well as Director of Neuroimaging for the Autism and Developmental Disorders Research Program at Stanford. My innovative research studies clinical aspects of cognitive and behavioral neuroscience, with a special focus on examining the neural circuitry associated with important brain-behavior relationships that may underlie different psychological and psychiatric domains in autistic children, adolescents, and adults. The ultimate goal of this research is to improve our understanding of the development of different cognitive and behavioral skills in order to develop mechanistically driven interventions that will improve precision medicine for mental health. Biologically based diagnosis and treatment are extremely limited for most psychological and psychiatric conditions but also critically needed to increase early identification and improve treatment outcomes, especially for neurodevelopmental disorders in which early intervention is the most beneficial. My early career research has primarily focused on clinical neuroscience using neuroimaging (e.g., MRI & EEG) to examine the effects of different drugs and behavioral interventions on the brain, especially for developing biomarkers for improving treatment planning and monitoring biological changes in response to single dose and clinical trials.
My primary contributions to science thus far fall within these major categories: 1) identifying the neural correlates of individual differences in cognition and behavior, 2) developing new interventions and investigating the neurobiological substrates of response to treatment, 3) examining different factors that contribute to brain development, 4) summarizing and increasing accessibility to autism-related research, and 5) methods development for neuroimaging studies. My earliest research investigated the neurobiology of alexithymia, dyslexia, and stress using structural and functional magnetic resonance imaging to test theories of the mechanisms that contribute to differences in cognition and behavior. My subsequent dissertation research, in which I began to focus on neurodevelopmental disorders, examined the neural correlates of response to beta-blockers in autistic adults and also assessed the contribution of cerebellar circuits to the autism phenotype. During my postdoctoral training, I have developed further skills for working with children in multiple clinical research settings, especially for using advanced neuroimaging approaches to examine important brain-behavior relationships. This includes a recent K99/R00 from the National Institute of Child Health and Human Development (NCT04278898 & NCT05664789) that will assess the neurobiology of restricted and repetitive behaviors in autistic children and examine the efficacy and target engagement of a novel nutritional supplement and investigational drug, N-acetylcysteine (NAC), in the brain. You can find more information about our NAC studies at https://redcap.link/NACandAutism. -
Sarah Heilshorn
Rickey/Nielsen Professor in the School of Engineering and Professor, by courtesy, of Bioengineering and of Chemical Engineering
Current Research and Scholarly InterestsProtein engineering
Tissue engineering
Regenerative medicine
Biomaterials -
Wm. LeRoy Heinrichs
Member, Maternal & Child Health Research Institute (MCHRI)
Current Research and Scholarly InterestsSurgical simulation; team-training in virtual environments; online training of healthcare providers in virtual environments; tele-medicine for acute & chronic disease management in virtual environments
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Stefan Heller, PhD, MS
Edward C. and Amy H. Sewall Professor in the School of Medicine and Professor of Otolaryngology - Head & Neck Surgery (OHNS)
Current Research and Scholarly InterestsOur research focuses on the inner ear, from its earliest manifestation as one of the cranial placodes until it has developed into a mature and functioning organ. We are interested in how the sensory epithelia of the inner ear that harbor the sensory hair cells develop, how the cells mature, and how these epithelia respond to toxic insults. The overarching goal of this research is to find ways to regenerate lost sensory hair cells in mammals.
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Rachel E. Herdes
Clinical Assistant Professor, Pediatrics - Gastroenterology
Current Research and Scholarly InterestsAs a pediatric physician-investigator, I strive to understand the role of nutrition and diet therapy in pediatric health. I am particularly interested in understanding and developing novel treatment plans for adolescent patients with obesity and in establishing guidelines to improve health outcomes for pediatric intestinal failure patients.
Current research studies include novel treatment options for pediatric metabolic dysfunction-associated steatotic liver disease (MASLD), health equity in pediatric patients with intestinal failure, and medication management after metabolic and bariatric surgery in pediatric patients with severe obesity. -
Ixel Hernandez-Castro
Postdoctoral Scholar, Epidemiology
BioEnvironmental epidemiologist focused on understanding how cumulative environmental exposures during pregnancy and early life shape maternal and child health across the life course. My work integrates epidemiologic methods and molecular biomarkers to uncover shared biological pathways linking chemical and social exposures to cardiometabolic and neurodevelopmental outcomes, with the goal of informing early prevention strategies and supporting health.
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Matthew (Matt) Hernandez
Assistant Professor of Pathology (Clinical)
Current Research and Scholarly InterestsDevelopment and optimization of infectious disease diagnostics; microbial genomics and pathogen surveillance; and the interplay between microbial diversity and clinical disease phenotypes.
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Tina Hernandez-Boussard
Professor of Medicine (Biomedical Informatics), of Biomedical Data Science, of Surgery and, by courtesy, of Epidemiology and Population Health
Current Research and Scholarly InterestsMy background and expertise is in the field of computational biology, with concentration in health services research. A key focus of my research is to apply novel methods and tools to large clinical datasets for hypothesis generation, comparative effectiveness research, and the evaluation of quality healthcare delivery. My research involves managing and manipulating big data, which range from administrative claims data to electronic health records, and applying novel biostatistical techniques to innovatively assess clinical and policy related research questions at the population level. This research enables us to create formal, statistically rigid, evaluations of healthcare data using unique combinations of large datasets.
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Lynn Hildemann
Wayne Loel Professor of Sustainability and Senior Associate Dean for Education
BioLynn Hildemann's current research areas include the sources and dispersion of airborne particulate matter indoors, and assessment of human exposure to air pollutants.
Prof. Hildemann received BS, MS, and PhD degrees in environmental engineering science from the California Institute of Technology. She is an author on >100 peer-reviewed publications, including two with over 1000 citations each, and another 6 with over 500 citations each. She has been honored with Young Investigator Awards from NSF and ONR, the Kenneth T. Whitby Award from the AAAR (1998), and Stanford's Gores Award for Teaching Excellence (2013); she also was a co-recipient of Atmospheric Environment’s Haagen-Smit Outstanding Paper Award (2001).
She has served on advisory committees for the Bay Area Air Quality Management District and for the California Air Resources Board. She has been an Associate Editor for Environmental Science & Technology, and Aerosol Science and Technology, and has served on the advisory board for the journal Environmental Science & Technology.
At Stanford, Prof. Hildemann has been chair of the Department of Civil & Environmental Engineering, and served as an elected member of the Faculty Senate. She has chaired the School of Engineering Library Committee, the University Committee on Judicial Affairs, and the University Breadth Governance Board. -
Paula Hillard
Professor of Obstetrics and Gynecology (General Gynecology), Emerita
BioPaula J. Adams Hillard, M.D., is Professor of Obstetrics and Gynecology at Stanford University School of Medicine where she serves as Associate Chair for Medical Student Education. She earned a B.S. in Zoology from the University of North Carolina and obtained her M.D. from Stanford University School of Medicine. She completed a residency in OB/Gyn at the University of North Carolina, Chapel Hill. She was on the faculty at the University of Virginia, and served as Professor in the Departments of OB/Gyn and Pediatrics at the Cincinnati Children’s Hospital (CCHMC) /University of Cincinnati Medical Center for 23 years. At CCHMC she was the founder of a postgraduate fellowship training program in Pediatric and Adolescent Gynecology. She currently directs the program in Pediatric and Adolescent Gynecology at the Lucile Packard Children’s Hospital at Stanford.
She has been active on a number of national medical committees, including chair of the American College Obstetricians and Gynecologists' (ACOG) Committees on Patient Education, Adolescent Health, and Guidelines for Women’s Health; she is a past member of the Gynecologic Practice Committee, the Gynecology Document Review Committee, and the Ethics Committee. She was been an examiner for the American Board of Obstetricians and Gynecologists from 1991-2015. She is a Board Member of the Association of Professors of Gynecology and Obstetrics, and was elected a fellow of the American Gynecological and Obstetrical Society. She is a past president of the North American Society for Pediatric and Adolescent Gynecology, and is an active contributor to the literature in adolescent gynecology and contraception with over 200 journal articles and abstracts published. She serves as Editor-in-Chief of the Journal of Pediatric and Adolescent Gynecology. She is the sole editor of two textbooks: the 5-Minute Consult in Obstetrics and Gynecology (2008) and Practical Pediatric and Adolescent Gynecology (2013). She is the author of over 120 book chapters on women’s health. She has been a consultant and a member of tasks forces and committees for the CDC, the U.S. FDA, the NICHD, the AMA, American Cancer Society, and ACOG. In addition to her work as a member of editorial boards and as an ad hoc reviewer for professional publications, Dr. Hillard has extensive experience with the consumer press. She was a contributing editor to Parents magazine from 1982-1990, writing a monthly column on pregnancy and birth--and currently acts as an editorial consultant to women’s publications such as Good Housekeeping, Family Circle, Woman’s Day, Cosmopolitan, Redbook, Glamour, YM, and Seventeen, as well as ABC News. She is a consultant to and a member of the medical advisory board of Clue, a menstrual cycle tracking app. She has been recognized for her teaching, and has been selected as one of 18 senior faculty master teachers/mentors for medical students at the Stanford University School of Medicine in a formal mentoring program called Educators for CARE: Compassion, Advocacy, Responsibility, and Empathy. -
Susan R. Hintz, M.D., M.S. Epi.
Robert L. Hess Family Professor and Professor, by courtesy, of Obstetrics and Gynecology
Current Research and Scholarly Interests1) Early childhood neurodevelopmental outcomes, mortality and morbidities of extremely premature and high-risk infants
2) Use of advanced neuroimaging and other predictors of neurodevelopmental outcomes in high-risk infants, evidence-based interventions to improve outcomes
3) Quality and process improvement throughout the continuum of care
4) Natural history and outcomes of complex fetal anomalies, implementing innovative fetal therapies. -
Jon Hochstein
Resident in Cardiothoracic Surgery - Thoracic Surgery
Affiliate, Department FundsBioI'm a Cardiothoracic Surgery resident at Stanford Health Care. I also completed an intern year in Pediatrics resident at Boston Children’s Hospital before transitioning to cardiothoracic surgery. I received my MD from Harvard Medical School in the Health Sciences and Technology program joint with MIT. I trained as a biomedical engineering at the Johns Hopkins University with a focus in instrumentation.
I've interests in medical devices spanning from assistive robotics, surgical devices, to point of care devices. I have extensive experience working in the electronics and coding aspect of device development.
My long term goal is to become a congenital cardiovascular surgeon and improve the field of transplantation (partial and whole), congenital cardiac surgery techniques, and congenital mechanical circulatory support. This vocation comes from my personal experience receiving a heart transplant in 1999.
